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PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Oncoimmunology, 2018-06, Vol.7 (6), p.e1433981-e1433981

2018

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Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses

Nature immunology, 2022-02, Vol.23 (2), p.262-274

2022

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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Nature Medicine, 2013-01, Vol.19 (1), p.57-64

2013

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Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis

PloS one, 2012-03, Vol.7 (3), p.e33418-e33418

2012

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Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance

Cancer research (Chicago, Ill.), 2019-12, Vol.79 (23), p.5958-5970

2019

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Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy

Journal for immunotherapy of cancer, 2021-06, Vol.9 (6), p.e002157

2021

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

The Journal of clinical investigation, 2008-12, Vol.118 (12), p.3930-3942

2008

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IRF8-dependent molecular complexes control the Th9 transcriptional program

Nature communications, 2017-12, Vol.8 (1), p.2085-13, Article 2085

2017

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Bleomycin exerts ambivalent antitumor immune effect by triggering both immunogenic cell death and proliferation of regulatory T cells

PloS one, 2013-06, Vol.8 (6), p.e65181-e65181

2013

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Dacarbazine-Mediated Upregulation of NKG2D Ligands on Tumor Cells Activates NK and CD8 T Cells and Restrains Melanoma Growth

Journal of investigative dermatology, 2013-02, Vol.133 (2), p.499-508

2013

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Valrubicin-loaded immunoliposomes for specific vesicle-mediated cell death in the treatment of hematological cancers

Cell death & disease, 2024-05, Vol.15 (5), p.328-328, Article 328

2024

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CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells

Journal for immunotherapy of cancer, 2022-01, Vol.10 (1)

2022

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NLRP6 negatively regulates type 2 immune responses in mice

Allergy (Copenhagen), 2022-11, Vol.77 (11), p.3320-3336

2022

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Only missense mutations affecting the DNA binding domain of p53 influence outcomes in patients with breast carcinoma

PloS one, 2013-01, Vol.8 (1), p.e55103-e55103

2013

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Protein Kinase Inhibitor-Mediated Immunoprophylactic and Immunotherapeutic Control of Colon Cancer

Frontiers in immunology, 2022-04, Vol.13, p.875764-875764

2022

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Regulation of Monocarboxylate Transporter MCT1 Expression by p53 Mediates Inward and Outward Lactate Fluxes in Tumors

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (4), p.939-948

2012

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Regulation of T cell antitumor immune response by tumor induced metabolic stress

Cell Stress, 2018-11, Vol.3 (1), p.9-18

2018

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Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX-Bevacizumab Drug Treatment Regimen

Cancer research (Chicago, Ill.), 2016-09, Vol.76 (18), p.5241-5252

2016

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Role of Cytokines and Chemokines in Angiogenesis in a Tumor Context

Cancers, 2022-05, Vol.14 (10), p.2446

2022

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Canonical and non-canonical functions of NLRP3

Journal of advanced research, 2023-11, Vol.53, p.137-151

2023

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GTN Enhances Antitumor Effects of Doxorubicin in TNBC by Targeting the Immunosuppressive Activity of PMN-MDSC

Cancers, 2023-06, Vol.15 (12), p.3129

2023

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The Tumor Microenvironment Impairs Th1 IFNγ Secretion through Alternative Splicing Modifications of Irf1 Pre-mRNA

Cancer immunology research, 2021-03, Vol.9 (3), p.324-336

2021

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Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (7), p.2550-2560

2011

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SOCS3 Transactivation by PPARγ Prevents IL-17-Driven Cancer Growth

Cancer research (Chicago, Ill.), 2013-06, Vol.73 (12), p.3578-3590

2013

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PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis

Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance

Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

IRF8-dependent molecular complexes control the Th9 transcriptional program

Bleomycin exerts ambivalent antitumor immune effect by triggering both immunogenic cell death and proliferation of regulatory T cells

Dacarbazine-Mediated Upregulation of NKG2D Ligands on Tumor Cells Activates NK and CD8 T Cells and Restrains Melanoma Growth

Valrubicin-loaded immunoliposomes for specific vesicle-mediated cell death in the treatment of hematological cancers

CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells

NLRP6 negatively regulates type 2 immune responses in mice

Only missense mutations affecting the DNA binding domain of p53 influence outcomes in patients with breast carcinoma

Protein Kinase Inhibitor-Mediated Immunoprophylactic and Immunotherapeutic Control of Colon Cancer

Regulation of Monocarboxylate Transporter MCT1 Expression by p53 Mediates Inward and Outward Lactate Fluxes in Tumors

Regulation of T cell antitumor immune response by tumor induced metabolic stress

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX-Bevacizumab Drug Treatment Regimen

Role of Cytokines and Chemokines in Angiogenesis in a Tumor Context

Canonical and non-canonical functions of NLRP3

GTN Enhances Antitumor Effects of Doxorubicin in TNBC by Targeting the Immunosuppressive Activity of PMN-MDSC

The Tumor Microenvironment Impairs Th1 IFNγ Secretion through Alternative Splicing Modifications of Irf1 Pre-mRNA

Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis

SOCS3 Transactivation by PPARγ Prevents IL-17-Driven Cancer Growth

The transfer of multigene panel testing for hereditary breast and ovarian cancer to healthcare: What are the implications for the management of patients and families?

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