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Activation mechanism of ATP-sensitive K + channels explored with real-time nucleotide binding

eLife, 2019-02, Vol.8

2019

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Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

The Journal of general physiology, 2014-04, Vol.143 (4), p.449-464

2014

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Editorial: Ion channels and transporters in diabetes and metabolic diseases

Frontiers in pharmacology, 2022-08, Vol.13, p.975812-975812

2022

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Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes

Diabetologia, 2016-06, Vol.59 (6), p.1162-1166

2016

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Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump

PLoS genetics, 2017-05, Vol.13 (5), p.e1006763-e1006763

2017

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NMDA Receptor Antagonists Increase the Release of GLP-1 From Gut Endocrine Cells

Frontiers in pharmacology, 2022-04, Vol.13, p.861311-861311

2022

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Neonatal Diabetes and the K ATP Channel: From Mutation to Therapy

Trends in endocrinology and metabolism, 2017-05, Vol.28 (5), p.377-387

2017

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The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

The Journal of general physiology, 2010-07, Vol.136 (1), p.63-82

2010

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Hybrid Function of the Na/K-ATPase: Proton Import Accompanying Na/K Exchange

Biophysical journal, 2016-02, Vol.110 (3), p.365a-365a

2016

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Neonatal Diabetes and the KATP Channel: From Mutation to Therapy

Trends in endocrinology and metabolism, 2017-05, Vol.28 (5), p.377-387

2017

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The release of GLP‐1 from gut L cells is inhibited by low extracellular pH

Obesity (Silver Spring, Md.), 2024-10, Vol.32 (10), p.1819-1824

2024

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Pore-Forming Properties of Alamethicin F50/5 Inserted in a Biological Membrane

Chemistry & biodiversity, 2007-06, Vol.4 (6), p.1338-1346

2007

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Nucleotide Modulation of KATP Channels Disentangled with FRET

Biophysical journal, 2019-02, Vol.116 (3), p.108-109a

2019

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The dynamic interplay of PIP2 and ATP in the regulation of the KATP channel

The Journal of physiology, 2022-10, Vol.600 (20), p.4503-4519

2022

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A loss-of-function mutation in KCNJ11 causing sulfonylurea-sensitive diabetes in early adult life

Diabetologia, 2024-05, Vol.67 (5), p.940-951

2024

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Role of the C-terminus of SUR in the differential regulation of β-cell and cardiac K ATP channels by MgADP and metabolism

The Journal of physiology, 2018-12, Vol.596 (24), p.6205-6217

2018

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The dynamic interplay of PIP 2 and ATP in the regulation of the K ATP channel

The Journal of physiology, 2022-10, Vol.600 (20), p.4503-4519

2022

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A Novel, Spectroscopic Window into Nucleotide Activation of KATP Channels

Biophysical journal, 2017-02, Vol.112 (3), p.421a-421a

2017

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Proton Current through Stalled Na/K-ATPase Pumps: Three Residues Point to a Possible Route and Mechanism

Biophysical journal, 2013-01, Vol.104 (2), p.22a-22a

2013

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The Nucleotide-Binding Sites of SUR1: A Mechanistic Model

Biophysical journal, 2015-12, Vol.109 (12), p.2452-2460

2015

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Role of the C‐terminus of SUR in the differential regulation of β‐cell and cardiac KATP channels by MgADP and metabolism

The Journal of physiology, 2018-12, Vol.596 (24), p.6205-6217

2018

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Differential Metabolic and Nucleotide Sensitivity of Beta-Cell and Cardiac KATP Channels

Biophysical journal, 2018-02, Vol.114 (3), p.203a-204a

2018

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Visualizing Adenine Nucleotide Regulation of the KATP Channel

Biophysical journal, 2018-02, Vol.114 (3), p.25a-26a

2018

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Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk

Diabetologia, 2016-07, Vol.59 (7), p.1430-1436

2016

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Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2016-08, Vol.371 (1700), p.20150426

2016

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Activation mechanism of ATP-sensitive K + channels explored with real-time nucleotide binding

Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

Editorial: Ion channels and transporters in diabetes and metabolic diseases

Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes

Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump

NMDA Receptor Antagonists Increase the Release of GLP-1 From Gut Endocrine Cells

Neonatal Diabetes and the K ATP Channel: From Mutation to Therapy

The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

Hybrid Function of the Na/K-ATPase: Proton Import Accompanying Na/K Exchange

Neonatal Diabetes and the KATP Channel: From Mutation to Therapy

The release of GLP‐1 from gut L cells is inhibited by low extracellular pH

Pore-Forming Properties of Alamethicin F50/5 Inserted in a Biological Membrane

Nucleotide Modulation of KATP Channels Disentangled with FRET

The dynamic interplay of PIP2 and ATP in the regulation of the KATP channel

A loss-of-function mutation in KCNJ11 causing sulfonylurea-sensitive diabetes in early adult life

Role of the C-terminus of SUR in the differential regulation of β-cell and cardiac K ATP channels by MgADP and metabolism

The dynamic interplay of PIP 2 and ATP in the regulation of the K ATP channel

A Novel, Spectroscopic Window into Nucleotide Activation of KATP Channels

Proton Current through Stalled Na/K-ATPase Pumps: Three Residues Point to a Possible Route and Mechanism

The Nucleotide-Binding Sites of SUR1: A Mechanistic Model

Role of the C‐terminus of SUR in the differential regulation of β‐cell and cardiac KATP channels by MgADP and metabolism

Differential Metabolic and Nucleotide Sensitivity of Beta-Cell and Cardiac KATP Channels

Visualizing Adenine Nucleotide Regulation of the KATP Channel

Neonatal diabetes caused by a homozygous KCNJ11 mutation demonstrates that tiny changes in ATP sensitivity markedly affect diabetes risk

Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels

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