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Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic

The Journal of pharmacology and experimental therapeutics, 1992-01, Vol.260 (1), p.275

1992

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Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol

The Journal of pharmacology and experimental therapeutics, 1993-10, Vol.267 (1), p.331

1993

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Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587)

Clinical cancer research, 1998-08, Vol.4 (8), p.1887-1898

1998

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Neurotrophic 3,9-Bis[(alkylthio)methyl]- and -Bis(alkoxymethyl)-K-252a Derivatives

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1863-1869

1997

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Topiramate: Preclinical Evaluation of a Structurally Novel Anticonvulsant

Epilepsia (Copenhagen), 1994-03, Vol.35 (2), p.450-460

1994

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Structure−Activity Studies on Anticonvulsant Sugar Sulfamates Related to Topiramate. Enhanced Potency with Cyclic Sulfate Derivatives

Journal of medicinal chemistry, 1998-04, Vol.41 (8), p.1315-1343

1998

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Deposition of β/A4 Immunoreactivity and Neuronal Pathology in Transgenic Mice Expressing the Carboxyl-Terminal Fragment of the Alzheimer Amyloid Precursor in the Brain

Proceedings of the National Academy of Sciences - PNAS, 1992-11, Vol.89 (22), p.10857-10861

1992

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CEP-1347 (KT7515), a Semisynthetic Inhibitor of the Mixed Lineage Kinase Family

The Journal of biological chemistry, 2001-07, Vol.276 (27), p.25302-25308

2001

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Beneficial effects of insulin-like growth factor-I on wobbler mouse motoneuron disease

Journal of the neurological sciences, 1995-05, Vol.129 (MAI), p.122-126

1995

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Insulin-like Growth Factor-I: Potential for Treatment of Motor Neuronal Disorders

Experimental neurology, 1993-11, Vol.124 (1), p.73-88

1993

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Preservation of cholinergic activity and prevention of neuron death by CEP-1347/KT-7515 following excitotoxic injury of the nucleus basalis magnocellularis

Neuroscience, 1998-09, Vol.86 (2), p.461-471

1998

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CEP‐1347/KT‐7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Aβ‐induced cortical neuron apoptosis

Journal of neurochemistry, 2001-05, Vol.77 (3), p.849-863

2001

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Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse

The Journal of pharmacology and experimental therapeutics, 1987-05, Vol.241 (2), p.393

1987

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Systemic administration of rhIGF-I enhanced regeneration after sciatic nerve crush in mice

The Journal of pharmacology and experimental therapeutics, 1995-09, Vol.274 (3), p.1443

1995

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Aroyl(aminoacyl)pyrroles, a New Class of Anticonvulsant Agents

Journal of medicinal chemistry, 1997-05, Vol.40 (11), p.1578-1584

1997

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CEP-1347 increases ChAT activity in culture and promotes cholinergic neurone survival following fimbria-fornix lesion

Neuroreport, 2000-07, Vol.11 (10), p.2271-2276

2000

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A comparison of the antinociceptive responses to the GABA-receptor agonists THIP and baclofen

Neuropharmacology, 1985-03, Vol.24 (3), p.211-216

1985

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McN-5652: a highly potent inhibitor of serotonin uptake

The Journal of pharmacology and experimental therapeutics, 1988-12, Vol.247 (3), p.1032

1988

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Systemic dexamethasone administration increases septal Trk autophosphorylation in adult rats via an induction of nerve growth factor

Molecular pharmacology, 1994-03, Vol.45 (3), p.395-401

1994

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Substance P antagonists and analgesia: A review of the hypothesis

Life Sciences, 1988, Vol.43 (18), p.1419-1431

Vaught, Jeffry L.

1988

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Modulation of μ-mediated antinociception by δ agonists in the mouse: selective potentiation of morphine and normorphine by [D-Pen 2, D-Pen 5]enkephalin

European journal of pharmacology, 1989-06, Vol.165 (1), p.1-10

1989

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Examination of the involvement of supraspinal and spinal mu and delta opioid receptors in analgesia using the mu receptor deficient CXBK mouse

The Journal of pharmacology and experimental therapeutics, 1988-04, Vol.245 (1), p.13

1988

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Antinociceptive action of McN-5195 in rodents: a structurally novel (indolizine) analgesic with a nonopioid mechanism of action

The Journal of pharmacology and experimental therapeutics, 1990-10, Vol.255 (1), p.1

1990

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Differential effects of leucine and methionine enkephalin on morphine-induced analgesia, acute tolerance and dependence

The Journal of pharmacology and experimental therapeutics, 1979-01, Vol.208 (1), p.86

1979

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Etoperidone, trazodone and MCPP : in vitro and in vivo identification of serotonin 5-HT1A (antagonistic) activity

Psychopharmacologia, 1992-08, Vol.108 (3), p.320-326

1992

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Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic

Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol

Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587)

Neurotrophic 3,9-Bis[(alkylthio)methyl]- and -Bis(alkoxymethyl)-K-252a Derivatives

Topiramate: Preclinical Evaluation of a Structurally Novel Anticonvulsant

Structure−Activity Studies on Anticonvulsant Sugar Sulfamates Related to Topiramate. Enhanced Potency with Cyclic Sulfate Derivatives

Deposition of β/A4 Immunoreactivity and Neuronal Pathology in Transgenic Mice Expressing the Carboxyl-Terminal Fragment of the Alzheimer Amyloid Precursor in the Brain

CEP-1347 (KT7515), a Semisynthetic Inhibitor of the Mixed Lineage Kinase Family

Beneficial effects of insulin-like growth factor-I on wobbler mouse motoneuron disease

Insulin-like Growth Factor-I: Potential for Treatment of Motor Neuronal Disorders

Preservation of cholinergic activity and prevention of neuron death by CEP-1347/KT-7515 following excitotoxic injury of the nucleus basalis magnocellularis

CEP‐1347/KT‐7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Aβ‐induced cortical neuron apoptosis

Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse

Systemic administration of rhIGF-I enhanced regeneration after sciatic nerve crush in mice

Aroyl(aminoacyl)pyrroles, a New Class of Anticonvulsant Agents

CEP-1347 increases ChAT activity in culture and promotes cholinergic neurone survival following fimbria-fornix lesion

A comparison of the antinociceptive responses to the GABA-receptor agonists THIP and baclofen

McN-5652: a highly potent inhibitor of serotonin uptake

Systemic dexamethasone administration increases septal Trk autophosphorylation in adult rats via an induction of nerve growth factor

Substance P antagonists and analgesia: A review of the hypothesis

Modulation of μ-mediated antinociception by δ agonists in the mouse: selective potentiation of morphine and normorphine by [D-Pen 2, D-Pen 5]enkephalin

Examination of the involvement of supraspinal and spinal mu and delta opioid receptors in analgesia using the mu receptor deficient CXBK mouse

Antinociceptive action of McN-5195 in rodents: a structurally novel (indolizine) analgesic with a nonopioid mechanism of action

Differential effects of leucine and methionine enkephalin on morphine-induced analgesia, acute tolerance and dependence

Etoperidone, trazodone and MCPP : in vitro and in vivo identification of serotonin 5-HT1A (antagonistic) activity

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