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Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1)

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6693-6698

2011

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A high-speed liquid chromatography/tandem mass spectrometry platform using multiplexed multiple-injection chromatography controlled by single software and its application in discovery ADME screening

Rapid communications in mass spectrometry, 2013-04, Vol.27 (7), p.731-737

2013

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Development of an LC–MS/MS method for high throughput quantification of metformin uptake in transporter inhibition assays

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-09, Vol.967, p.211-218

2014

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A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen

Rapid communications in mass spectrometry, 2009-06, Vol.23 (11), p.1579-1591

2009

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An integrated bioanalytical platform for supporting high-throughput serum protein binding screening

Rapid communications in mass spectrometry, 2010-12, Vol.24 (24), p.3593-3601

2010

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Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11I super(2)-hydroxydehydrogenase 1 (11I super(2)-HSD1)

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6693-6698

2011

Volltextzugriff (PDF)

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Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1)

A high-speed liquid chromatography/tandem mass spectrometry platform using multiplexed multiple-injection chromatography controlled by single software and its application in discovery ADME screening

Development of an LC–MS/MS method for high throughput quantification of metformin uptake in transporter inhibition assays

A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen

An integrated bioanalytical platform for supporting high-throughput serum protein binding screening

Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11I super(2)-hydroxydehydrogenase 1 (11I super(2)-HSD1)

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