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Synthesis of Thiazolidin-4-Ones Derivatives, Evaluation of Conformation in Solution, Theoretical Isomerization Reaction Paths and Discovery of Potential Biological Targets

Molecules (Basel, Switzerland), 2024-05, Vol.29 (11), p.2458

2024

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Thiophosphinic Acids: Historic Overview and Recent Advances in their Synthesis and Applications

Current organic chemistry, 2011-07, Vol.15 (14), p.2469-2480

Vassiliou, Stamatia

2011

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Synthesis of α-Hydroxyphosphinates and Derivatives: Recent Advances

Mini-reviews in organic chemistry, 2015-05, Vol.12 (3), p.237-248

Vassiliou, Stamatia

2015

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Conformational Properties of New Thiosemicarbazone and Thiocarbohydrazone Derivatives and Their Possible Targets

Molecules (Basel, Switzerland), 2022-04, Vol.27 (8), p.2537

2022

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Conformational Properties and Putative Bioactive Targets for Novel Thiosemicarbazone Derivatives

Molecules (Basel, Switzerland), 2022-07, Vol.27 (14), p.4548

2022

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Rational Design and Synthesis of AT1R Antagonists

Molecules (Basel, Switzerland), 2021-05, Vol.26 (10), p.2927

2021

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Cbz-aminomethylphosphonic acid and its structural variations: synthesis from a common precursor and a stability study

ARKIVOC, 2012-01, Vol.2012 (4), p.7-14

2012

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Exploration of Thiourea-Based Scaffolds for the Construction of Bacterial Ureases Inhibitors

ACS omega, 2023-08, Vol.8 (31), p.28783-28796

2023

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Three component Kabachnik-Fields condensation leading to substituted aminomethane-P-hydroxymethylphosphonic acids as a tool for screening of bacterial urease inhibitors

ARKIVOC, 2011-11, Vol.2012 (4), p.33-43

2011

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The M18 Aspartyl Aminopeptidase of the Human Malaria Parasite Plasmodium falciparum

The Journal of biological chemistry, 2007-10, Vol.282 (42), p.30817-30826

2007

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Mapping the Pathway toward Thiophosphinic Pseudopeptides. Synthesis of Suitably Protected PG-Phe-Ψ[P(S)(OX)CH2]‑Gly-OY Analogues as Thiophosphinyl Dipeptide Isosters (TDI), a Comparative Study for Selective Deprotection and Further Elongation

Journal of organic chemistry, 2013-10, Vol.78 (20), p.10069-10076

2013

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A novel and efficient synthesis of 3,4-dihydroxyphenylacetic ester and amide derivatives/conjugates and assessment of their antioxidant activity

Natural product research, 2018-06, Vol.32 (11), p.1267-1273

2018

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Covalent Inhibition of Bacterial Urease by Bifunctional Catechol-Based Phosphonates and Phosphinates

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.404-416

2021

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Rapid and Efficient Microwave-Assisted Hydrophosphinylation of Unactivated Alkenes with H-Phosphinic Acids without Added Metal or Radical Initiator

Synlett, 2015-12, Vol.26 (19), p.2714-2719

2015

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RXP 407, a Phosphinic Peptide, Is a Potent Inhibitor of Angiotensin I Converting Enzyme Able to Differentiate between Its Two Active Sites

Proceedings of the National Academy of Sciences - PNAS, 1999-04, Vol.96 (8), p.4330-4335

1999

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A synthetic method for diversification of the P1′ substituent in phosphinic dipeptides as a tool for exploration of the specificity of the S1′ binding pockets of leucine aminopeptidases

Bioorganic & medicinal chemistry, 2007-05, Vol.15 (9), p.3187-3200

2007

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RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis

The Journal of pharmacology and experimental therapeutics, 2001-05, Vol.297 (2), p.606

2001

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Catechol-based inhibitors of bacterial urease

Bioorganic & medicinal chemistry letters, 2019-05, Vol.29 (9), p.1085-1089

2019

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Discovery of potent and selective inhibitors of human aminopeptidases ERAP1 and ERAP2 by screening libraries of phosphorus-containing amino acid and dipeptide analogues

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (16), p.4122-4126

2016

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Structural exploration of cinnamate-based phosphonic acids as inhibitors of bacterial ureases

European journal of medicinal chemistry, 2018-11, Vol.159, p.307-316

2018

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Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles

European journal of medicinal chemistry, 2017-06, Vol.133, p.107-120

2017

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Structure assignment, conformational properties and discovery of potential targets of the Ugi cinnamic adduct NGI25

Journal of biomolecular structure & dynamics, 2023-03, Vol.41 (4), p.1253-1266

2023

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Anticancer Potential of Novel Cinnamoyl Derivatives against U87MG and SHSY-5Y Cell Lines

Anti-cancer agents in medicinal chemistry, 2024, Vol.24 (1), p.39-49

2024

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Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation

European journal of medicinal chemistry, 2020-01, Vol.186, p.111880, Article 111880

2020

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Design, Synthesis, and Evaluation of Novel Organophosphorus Inhibitors of Bacterial Ureases

Journal of medicinal chemistry, 2008-09, Vol.51 (18), p.5736-5744

2008

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Synthesis of Thiazolidin-4-Ones Derivatives, Evaluation of Conformation in Solution, Theoretical Isomerization Reaction Paths and Discovery of Potential Biological Targets

Thiophosphinic Acids: Historic Overview and Recent Advances in their Synthesis and Applications

Synthesis of α-Hydroxyphosphinates and Derivatives: Recent Advances

Conformational Properties of New Thiosemicarbazone and Thiocarbohydrazone Derivatives and Their Possible Targets

Conformational Properties and Putative Bioactive Targets for Novel Thiosemicarbazone Derivatives

Rational Design and Synthesis of AT1R Antagonists

Cbz-aminomethylphosphonic acid and its structural variations: synthesis from a common precursor and a stability study

Exploration of Thiourea-Based Scaffolds for the Construction of Bacterial Ureases Inhibitors

Three component Kabachnik-Fields condensation leading to substituted aminomethane-P-hydroxymethylphosphonic acids as a tool for screening of bacterial urease inhibitors

The M18 Aspartyl Aminopeptidase of the Human Malaria Parasite Plasmodium falciparum

Mapping the Pathway toward Thiophosphinic Pseudopeptides. Synthesis of Suitably Protected PG-Phe-Ψ[P(S)(OX)CH2]‑Gly-OY Analogues as Thiophosphinyl Dipeptide Isosters (TDI), a Comparative Study for Selective Deprotection and Further Elongation

A novel and efficient synthesis of 3,4-dihydroxyphenylacetic ester and amide derivatives/conjugates and assessment of their antioxidant activity

Covalent Inhibition of Bacterial Urease by Bifunctional Catechol-Based Phosphonates and Phosphinates

Rapid and Efficient Microwave-Assisted Hydrophosphinylation of Unactivated Alkenes with H-Phosphinic Acids without Added Metal or Radical Initiator

RXP 407, a Phosphinic Peptide, Is a Potent Inhibitor of Angiotensin I Converting Enzyme Able to Differentiate between Its Two Active Sites

A synthetic method for diversification of the P1′ substituent in phosphinic dipeptides as a tool for exploration of the specificity of the S1′ binding pockets of leucine aminopeptidases

RXP 407, a selective inhibitor of the N-domain of angiotensin I-converting enzyme, blocks in vivo the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis

Catechol-based inhibitors of bacterial urease

Discovery of potent and selective inhibitors of human aminopeptidases ERAP1 and ERAP2 by screening libraries of phosphorus-containing amino acid and dipeptide analogues

Structural exploration of cinnamate-based phosphonic acids as inhibitors of bacterial ureases

Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles

Structure assignment, conformational properties and discovery of potential targets of the Ugi cinnamic adduct NGI25

Anticancer Potential of Novel Cinnamoyl Derivatives against U87MG and SHSY-5Y Cell Lines

Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation

Design, Synthesis, and Evaluation of Novel Organophosphorus Inhibitors of Bacterial Ureases

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