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The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

Expert review of vaccines, 2013-07, Vol.12 (7), p.809-819

2013

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Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

Nature (London), 2011-04, Vol.472 (7344), p.471-475

2011

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Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation

The Journal of immunology (1950), 2014-11, Vol.193 (9), p.4722-4731

2014

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Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

Journal for immunotherapy of cancer, 2019-09, Vol.7 (1), p.244-244, Article 244

2019

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Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8

The Journal of immunology (1950), 2005-02, Vol.174 (3), p.1259-1268

2005

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In situ monitoring by DSC and modeling of curing of vinyl polysiloxanes in layered silicate nanocomposites

Journal of thermal analysis and calorimetry, 2017-03, Vol.127 (3), p.2049-2058

2017

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Cutting Edge: Activation of Murine TLR8 by a Combination of Imidazoquinoline Immune Response Modifiers and PolyT Oligodeoxynucleotides

The Journal of immunology (1950), 2006-11, Vol.177 (10), p.6584-6587

2006

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First in Human Phase I Trial of 852A, a Novel Systemic Toll-like Receptor 7 Agonist, to Activate Innate Immune Responses in Patients with Advanced Cancer

Clinical cancer research, 2007-12, Vol.13 (23), p.7119-7125

2007

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TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth

JCI insight, 2017-03, Vol.2 (6), p.e91020-e91020

2017

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Comparison of human B cell activation by TLR7 and TLR9 agonists

BMC immunology, 2008-07, Vol.9 (1), p.39-39

2008

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Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors

Journal for immunotherapy of cancer, 2014-05, Vol.2 (1), p.12-12

2014

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Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists

International immunology, 2006-07, Vol.18 (7), p.1115-1126

2006

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Expression of estrogen receptors in melanoma and sentinel lymph nodes; a "female" clinical entity or a possible treatment modality?

European journal of gynaecological oncology, 2015, Vol.36 (2), p.123-130

2015

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Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN

The Journal of experimental medicine, 2004-03, Vol.199 (6), p.775-784

2004

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In vitro drug release studies from organoclay/poly(dimethyl siloxane) nanocomposite matrices

Journal of biomedical materials research. Part B, Applied biomaterials, 2012-10, Vol.100B (7), p.1899-1910

2012

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Binding of Soluble Yeast β-Glucan to Human Neutrophils and Monocytes is Complement-Dependent

Frontiers in immunology, 2013, Vol.4, p.230-230

2013

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Understanding nitrate formation in a world with less sulfate

Atmospheric chemistry and physics, 2018-09, Vol.18 (17), p.12765-12775

2018

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Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod

Cellular immunology, 2002-07, Vol.218 (1), p.74-86

2002

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Administration of a dual toll-like receptor 7 and toll-like receptor 8 agonist protects against influenza in rats

Antiviral research, 2007-01, Vol.73 (1), p.1-11

2007

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Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

BMC immunology, 2007-10, Vol.8 (1), p.26-26

2007

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Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells

Journal of translational medicine, 2007-01, Vol.5 (1), p.5-5, Article 5

2007

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TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN

Journal of interferon & cytokine research, 2008-04, Vol.28 (4), p.253-263

2008

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Aerosol acidity and liquid water content regulate the dry deposition of inorganic reactive nitrogen

Atmospheric chemistry and physics, 2021-04, Vol.21 (8), p.6023-6033

2021

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On the implications of aerosol liquid water and phase separation for organic aerosol mass

Atmospheric chemistry and physics, 2017-01, Vol.17 (1), p.343-369

2017

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Granzyme B expression is enhanced in human monocytes by TLR8 agonists and contributes to antibody-dependent cellular cytotoxicity

The Journal of immunology (1950), 2015-03, Vol.194 (6), p.2786-2795

2015

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The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation

Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8

In situ monitoring by DSC and modeling of curing of vinyl polysiloxanes in layered silicate nanocomposites

Cutting Edge: Activation of Murine TLR8 by a Combination of Imidazoquinoline Immune Response Modifiers and PolyT Oligodeoxynucleotides

First in Human Phase I Trial of 852A, a Novel Systemic Toll-like Receptor 7 Agonist, to Activate Innate Immune Responses in Patients with Advanced Cancer

TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth

Comparison of human B cell activation by TLR7 and TLR9 agonists

Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors

Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists

Expression of estrogen receptors in melanoma and sentinel lymph nodes; a "female" clinical entity or a possible treatment modality?

Combined TLR and CD40 triggering induces potent CD8+ T cell expansion with variable dependence on type I IFN

In vitro drug release studies from organoclay/poly(dimethyl siloxane) nanocomposite matrices

Binding of Soluble Yeast β-Glucan to Human Neutrophils and Monocytes is Complement-Dependent

Understanding nitrate formation in a world with less sulfate

Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod

Administration of a dual toll-like receptor 7 and toll-like receptor 8 agonist protects against influenza in rats

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells

TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN

Aerosol acidity and liquid water content regulate the dry deposition of inorganic reactive nitrogen

On the implications of aerosol liquid water and phase separation for organic aerosol mass

Granzyme B expression is enhanced in human monocytes by TLR8 agonists and contributes to antibody-dependent cellular cytotoxicity

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