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Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway

Cell metabolism, 2015-07, Vol.22 (1), p.77-85

2015

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Gestational Diabetes Mellitus Resulting From Impaired β-Cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen

Diabetes (New York, N.Y.), 2010-01, Vol.59 (1), p.143-152

2010

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LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation

Frontiers in endocrinology (Lausanne), 2022-05, Vol.13, p.867001-867001

2022

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Lactogens Promote Beta Cell Survival through JAK2/STAT5 Activation and Bcl-XL Upregulation

The Journal of biological chemistry, 2007-10, Vol.282 (42), p.30707-30717

2007

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Diabetes mellitus--advances and challenges in human β-cell proliferation

Nature reviews. Endocrinology, 2015-04, Vol.11 (4), p.201

2015

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Human β-cell proliferation and intracellular signaling: part 3

Diabetes (New York, N.Y.), 2015-06, Vol.64 (6), p.1872-1885

2015

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Targeted Inactivation of Hepatocyte Growth Factor Receptor c-met in β-Cells Leads to Defective Insulin Secretion and GLUT-2 Downregulation Without Alteration of β-Cell Mass

Diabetes (New York, N.Y.), 2005-07, Vol.54 (7), p.2090-2102

2005

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Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

Diabetes (New York, N.Y.), 2001-12, Vol.50 (12), p.2752-2762

2001

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Mapping and specific viral targeting of peripheral pancreatic innervation

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Adenovirus-mediated Hepatocyte Growth Factor Expression in Mouse Islets Improves Pancreatic Islet Transplant Performance and Reduces Beta Cell Death

The Journal of biological chemistry, 2003-01, Vol.278 (1), p.343-351

2003

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Hepatocyte growth factor/c-Met signaling is required for β-cell regeneration

Diabetes (New York, N.Y.), 2014-01, Vol.63 (1), p.216-223

2014

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Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function

Diabetes (New York, N.Y.), 2007-01, Vol.56 (1), p.57-64

2007

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Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus

Diabetes (New York, N.Y.), 2012-05, Vol.61 (5), p.1143-1152

2012

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PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

Diabetes (New York, N.Y.), 2016-05, Vol.65 (5), p.1283-1296

2016

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ChREBP Mediates Glucose-Stimulated Pancreatic β-cell Proliferation

Diabetes (New York, N.Y.), 2012-08, Vol.61 (8), p.2004-2015

2012

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PKC[zeta] Is Essential for Pancreatic [Beta]-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

Diabetes (New York, N.Y.), 2016-05, Vol.65 (5), p.1283

2016

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Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic β-Cell Death and Accelerates the Onset of Diabetes

Diabetes (New York, N.Y.), 2011-02, Vol.60 (2), p.525-536

2011

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The Retinoblastoma Protein and Its Homolog p130 Regulate the G1/S Transition in Pancreatic β-Cells

Diabetes (New York, N.Y.), 2009-08, Vol.58 (8), p.1852-1862

2009

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Overexpression of Parathyroid Hormone-Related Protein Inhibits Pancreatic β-Cell Death In Vivo and In Vitro

Diabetes (New York, N.Y.), 2002-10, Vol.51 (10), p.3003-3013

2002

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CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats

Molecular cancer research, 2017-11, Vol.15 (11), p.1531-1541

2017

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Parathyroid Hormone-Related Protein Enhances Human β-cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

Diabetes (New York, N.Y.), 2010-12, Vol.59 (12), p.3131-3138

2010

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RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes

Science advances, 2023-11, Vol.9 (44), p.eadf5238-eadf5238

2023

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Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

Diabetes (New York, N.Y.), 2011-10, Vol.60 (10), p.2546-2559

2011

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Growth factors and beta cell replication

The international journal of biochemistry & cell biology, 2006-01, Vol.38 (5), p.931-950

2006

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Hepatocyte Growth Factor Ameliorates Hyperglycemia and Corrects β-Cell Mass in IRS2-Deficient Mice

Molecular endocrinology (Baltimore, Md.), 2014-12, Vol.28 (12), p.2038-2048

2014

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Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway

Gestational Diabetes Mellitus Resulting From Impaired β-Cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen

LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation

Lactogens Promote Beta Cell Survival through JAK2/STAT5 Activation and Bcl-XL Upregulation

Diabetes mellitus--advances and challenges in human β-cell proliferation

Human β-cell proliferation and intracellular signaling: part 3

Targeted Inactivation of Hepatocyte Growth Factor Receptor c-met in β-Cells Leads to Defective Insulin Secretion and GLUT-2 Downregulation Without Alteration of β-Cell Mass

Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

Mapping and specific viral targeting of peripheral pancreatic innervation

Adenovirus-mediated Hepatocyte Growth Factor Expression in Mouse Islets Improves Pancreatic Islet Transplant Performance and Reduces Beta Cell Death

Hepatocyte growth factor/c-Met signaling is required for β-cell regeneration

Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function

Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus

PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

ChREBP Mediates Glucose-Stimulated Pancreatic β-cell Proliferation

PKC[zeta] Is Essential for Pancreatic [Beta]-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2

Disruption of Hepatocyte Growth Factor/c-Met Signaling Enhances Pancreatic β-Cell Death and Accelerates the Onset of Diabetes

The Retinoblastoma Protein and Its Homolog p130 Regulate the G1/S Transition in Pancreatic β-Cells

Overexpression of Parathyroid Hormone-Related Protein Inhibits Pancreatic β-Cell Death In Vivo and In Vitro

CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats

Parathyroid Hormone-Related Protein Enhances Human β-cell Proliferation and Function With Associated Induction of Cyclin-Dependent Kinase 2 and Cyclin E Expression

RANKL/RANK is required for cytokine-induced beta cell death; osteoprotegerin, a RANKL inhibitor, reverses rodent type 1 diabetes

Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

Growth factors and beta cell replication

Hepatocyte Growth Factor Ameliorates Hyperglycemia and Corrects β-Cell Mass in IRS2-Deficient Mice

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