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A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies

Genes & development, 2024-03, Vol.38 (5-6), p.253-272

2024

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Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo

Genes & development, 2008-06, Vol.22 (12), p.1677-1689

2008

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Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

Cell reports (Cambridge), 2021-09, Vol.36 (11), p.109675-109675, Article 109675

2021

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Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

Cell stem cell, 2010-03, Vol.6 (3), p.251-264

2010

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Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics

Nature communications, 2022-03, Vol.13 (1), p.1584-1584, Article 1584

2022

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Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells

The Journal of clinical investigation, 2011-03, Vol.121 (3), p.1207-1216

2011

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Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.2032-2045

2015

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Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

Cell stem cell, 2008-12, Vol.3 (6), p.611-624

2008

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A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells

Stem cell reports, 2017-06, Vol.8 (6), p.1563-1572

2017

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Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling

Journal of cell science, 2000-12, Vol.113 Pt 23 (23), p.4313-4318

2000

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The intracellular domains of Notch1 and 2 are functionally equivalent during development and carcinogenesis

Development (Cambridge), 2015-01

2015

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E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors

The Journal of immunology (1950), 2008-11, Vol.181 (9), p.5885-5894

2008

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The Interaction of the Wnt and Notch Pathways Modulates Natural Killer Versus T Cell Differentiation

Stem cells (Dayton, Ohio), 2007-10, Vol.25 (10), p.2488-2497

2007

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The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells

Blood, 1998-06, Vol.91 (11), p.4084-4091

1998

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Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

Blood, 2005-10, Vol.106 (8), p.2693-2699

2005

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Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability

Blood, 2003-03, Vol.101 (5), p.1784-1789

2003

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Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

Nature medicine, 2000-11, Vol.6 (11), p.1278-1281

2000

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Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells

The Journal of experimental medicine, 2005-05, Vol.201 (9), p.1361-1366

2005

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Delta-1 enhances marrow and thymus repopulating ability of human CD34+CD38– cord blood cells

The Journal of clinical investigation, 2002-10, Vol.110 (8), p.1165-1174

2002

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The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

Development (Cambridge), 2015-07, Vol.142 (14), p.2452-2463

2015

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"Dynamic morphology system": A method for quantitating changes in shape, pseudopod formation, and motion in normal and mutant amoebae of Dictyostelium discoideum

Journal of cellular biochemistry, 1988-06, Vol.37 (2), p.177-192

1988

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Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells

The Journal of clinical investigation, 2002-10, Vol.110 (8), p.1165-1174

2002

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Clonal analysis of hematopoietic stem cell precursors reveals developmental evolution of phenotypic and functional properties

Experimental hematology, 2016-09, Vol.44 (9), p.S78-S78

2016

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Single Cell Transcriptomics Maps the Embryonic Emergence of HSC and Identifies Intercellular Interactions Regulating HSC Genesis

Blood, 2018-11, Vol.132 (Supplement 1), p.5086-5086

2018

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Clonal Analysis Reveals Functional and Transcriptional Heterogeneity of Self-Renewing Fetal Liver Hematopoietic Stem Cells

Blood, 2022-11, Vol.140 (Supplement 1), p.8574-8575

2022

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A germline point mutation in the MYC-FBW7 phosphodegron initiates hematopoietic malignancies

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo

Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells

Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity

A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells

Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling

The intracellular domains of Notch1 and 2 are functionally equivalent during development and carcinogenesis

E47 Controls the Developmental Integrity and Cell Cycle Quiescence of Multipotential Hematopoietic Progenitors

The Interaction of the Wnt and Notch Pathways Modulates Natural Killer Versus T Cell Differentiation

The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells

Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells

Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells

Delta-1 enhances marrow and thymus repopulating ability of human CD34+CD38– cord blood cells

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis

"Dynamic morphology system": A method for quantitating changes in shape, pseudopod formation, and motion in normal and mutant amoebae of Dictyostelium discoideum

Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells

Clonal analysis of hematopoietic stem cell precursors reveals developmental evolution of phenotypic and functional properties

Single Cell Transcriptomics Maps the Embryonic Emergence of HSC and Identifies Intercellular Interactions Regulating HSC Genesis

Clonal Analysis Reveals Functional and Transcriptional Heterogeneity of Self-Renewing Fetal Liver Hematopoietic Stem Cells

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