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Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Pharmaceutical research, 2012-10, Vol.29 (10), p.2860-2873

2012

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The impacts of shape factor and heat transfer on two-phase flow of nano and hybrid nanofluid in a saturated porous medium

Scientific reports, 2022-12, Vol.12 (1), p.21864-21864, Article 21864

2022

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Mechanistic Modeling to Predict the Transporter- and Enzyme-Mediated Drug-Drug Interactions of Repaglinide

Pharmaceutical research, 2013-04, Vol.30 (4), p.1188-1199

2013

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Predicting the Human Hepatic Clearance of Acidic and Zwitterionic Drugs

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11831-11844

2020

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Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

Journal of medicinal chemistry, 2010-02, Vol.53 (3), p.1098-1108

2010

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Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes

Molecular pharmaceutics, 2018-08, Vol.15 (8), p.3227-3235

2018

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A Thermal Analysis of a Convective–Radiative Porous Annular Fin Wetted in a Ternary Nanofluid Exposed to Heat Generation under the Influence of a Magnetic Field

Energies (Basel), 2023-09, Vol.16 (17), p.6155

2023

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Entropy Generation Optimization in Couple Stress Fluid Flow with Variable Viscosity and Aligned Magnetic Field

Sustainability, 2023-01, Vol.15 (3), p.2493

2023

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A Free Convective Two-Phase Flow of Optically Thick Radiative Ternary Hybrid Nanofluid in an Inclined Symmetrical Channel through a Porous Medium

Symmetry (Basel), 2023-08, Vol.15 (8), p.1615

2023

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Influence of cracks on fracture strength and electric power losses in Silicon solar cells at high temperatures: deep machine learning and molecular dynamics approach

Applied physics. A, Materials science & processing, 2023-06, Vol.129 (6), Article 408

2023

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Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance

Clinical pharmacology and therapeutics, 2022-09, Vol.112 (3), p.485-500

2022

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Biomarker‐Informed Model‐Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug‐Drug Interactions

Clinical pharmacology and therapeutics, 2022-02, Vol.111 (2), p.404-415

2022

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Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System

Drug metabolism and disposition, 2018-05, Vol.46 (5), p.729-739

2018

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Dynamics of Heat Transfer Analysis of Convective-Radiative Fins with Variable Thermal Conductivity and Heat Generation: Differential Transformation Method

Mathematics (Basel), 2022-10, Vol.10 (20), p.3814

2022

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Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes

The Journal of pharmacology and experimental therapeutics, 2019-07, Vol.370 (1), p.72-83

2019

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Organic Anion Transporter 2–Mediated Hepatic Uptake Contributes to the Clearance of High-Permeability–Low-Molecular-Weight Acid and Zwitterion Drugs: Evaluation Using 25 Drugs

The Journal of pharmacology and experimental therapeutics, 2018-11, Vol.367 (2), p.322-334

2018

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Effect of Human Plasma on Hepatic Uptake of Organic Anion-Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes

Drug metabolism and disposition, 2021-01, Vol.49 (1), p.72-83

2021

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Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state

Expert opinion on drug metabolism & toxicology, 2010-08, Vol.6 (8), p.939-952

2010

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On thermal performance of spine fin in magnetized hybrid fluid rooted with Cu and MoS4 nanoparticles

AIP advances, 2024-01, Vol.14 (1), p.015068-015068-10

2024

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Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug

The Journal of pharmacology and experimental therapeutics, 2018-03, Vol.364 (3), p.390-398

2018

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Functional Role of P-Glycoprotein in Limiting Intestinal Absorption of Drugs: Contribution of Passive Permeability to P-Glycoprotein Mediated Efflux Transport

Molecular pharmaceutics, 2005-01, Vol.2 (1), p.12-21

2005

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Membrane transporters in drug development and as determinants of precision medicine

Nature reviews. Drug discovery, 2024-04, Vol.23 (4), p.255-280

2024

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Predicting Human Clearance of Organic Anion Transporting Polypeptide Substrates Using Cynomolgus Monkey: In Vitro-In Vivo Scaling of Hepatic Uptake Clearance

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.989-1000

2018

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Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1

Drug metabolism and disposition, 2019-05, Vol.47 (5), p.493-503

2019

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Failure Analysis of Silicon Solar Cells in the Presence of Cracks: Correlated to Partial Shading

Journal of failure analysis and prevention, 2023-12, Vol.23 (6), p.2511-2518

Siruvuri, S. D. V. S. S. Varma

2023

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Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

The impacts of shape factor and heat transfer on two-phase flow of nano and hybrid nanofluid in a saturated porous medium

Mechanistic Modeling to Predict the Transporter- and Enzyme-Mediated Drug-Drug Interactions of Repaglinide

Predicting the Human Hepatic Clearance of Acidic and Zwitterionic Drugs

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

Quantification of Hepatic Organic Anion Transport Proteins OAT2 and OAT7 in Human Liver Tissue and Primary Hepatocytes

A Thermal Analysis of a Convective–Radiative Porous Annular Fin Wetted in a Ternary Nanofluid Exposed to Heat Generation under the Influence of a Magnetic Field

Entropy Generation Optimization in Couple Stress Fluid Flow with Variable Viscosity and Aligned Magnetic Field

A Free Convective Two-Phase Flow of Optically Thick Radiative Ternary Hybrid Nanofluid in an Inclined Symmetrical Channel through a Porous Medium

Influence of cracks on fracture strength and electric power losses in Silicon solar cells at high temperatures: deep machine learning and molecular dynamics approach

Transporters in Drug Development: International Transporter Consortium Update on Emerging Transporters of Clinical Importance

Biomarker‐Informed Model‐Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug‐Drug Interactions

Navigating Transporter Sciences in Pharmacokinetics Characterization Using the Extended Clearance Classification System

Dynamics of Heat Transfer Analysis of Convective-Radiative Fins with Variable Thermal Conductivity and Heat Generation: Differential Transformation Method

Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes

Organic Anion Transporter 2–Mediated Hepatic Uptake Contributes to the Clearance of High-Permeability–Low-Molecular-Weight Acid and Zwitterion Drugs: Evaluation Using 25 Drugs

Effect of Human Plasma on Hepatic Uptake of Organic Anion-Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes

Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state

On thermal performance of spine fin in magnetized hybrid fluid rooted with Cu and MoS4 nanoparticles

Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug

Functional Role of P-Glycoprotein in Limiting Intestinal Absorption of Drugs: Contribution of Passive Permeability to P-Glycoprotein Mediated Efflux Transport

Membrane transporters in drug development and as determinants of precision medicine

Predicting Human Clearance of Organic Anion Transporting Polypeptide Substrates Using Cynomolgus Monkey: In Vitro-In Vivo Scaling of Hepatic Uptake Clearance

Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1

Failure Analysis of Silicon Solar Cells in the Presence of Cracks: Correlated to Partial Shading

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