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Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1

Gene therapy, 2006-02, Vol.13 (3), p.225-234

2006

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WVE-210201, an investigational stereopure oligonucleotide therapy for Duchenne muscular dystrophy, induces Exon 51 skipping and dystrophin protein restoration

Neuromuscular disorders : NMD, 2017-10, Vol.27, p.S217

2017

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

Nature biotechnology, 2005-08, Vol.23 (8), p.1002-1007

2005

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Intimal hyperplasia recurs after removal of PDGF-AB and -BB inhibition in the rat carotid artery injury model

Arteriosclerosis, thrombosis, and vascular biology, 2000-11, Vol.20 (11), p.E89

2000

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Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

Hepatology (Baltimore, Md.), 2005-06, Vol.41 (6), p.1349-1356

2005

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P.193 Phosphoryl guanidine-containing backbone modifications enhance exon skipping, dystrophin restoration and survival in a severe mouse model for DMD

Neuromuscular disorders : NMD, 2022-10, Vol.32, p.S126

2022

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THU-030 - Stereochemistry enhances pharmacological properties of APOC3 antisense oligonucleotides

Journal of hepatology, 2018-04, Vol.68, p.S137-S137

2018

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Stereochemistry enhances pharmacological properties of APOC3 antisense oligonucleotides

Journal of hepatology, 2018-04, Vol.68, p.S137

2018

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Preclinical studies of WVE-210201, an investigational stereopure antisense oligonucleotide in development for the treatment of patients with duchenne muscular dystrophy (DMD)

Journal of the neurological sciences, 2017-10, Vol.381, p.277-278

2017

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P.402 - WVE-210201, an investigational stereopure oligonucleotide therapy for Duchenne muscular dystrophy, induces Exon 51 skipping and dystrophin protein restoration

Neuromuscular disorders : NMD, 2017-10, Vol.27, p.S217-S217

2017

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Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA

Journal of viral hepatitis, 2002-11, Vol.9 (6), p.411-418

2002

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DMD CLINICAL THERAPIES II

Neuromuscular disorders : NMD, 2018-10, Vol.28, p.S67

2018

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DMD CLINICAL THERAPIES II: P.127Identification of potent, muscle-targeting investigational stereo-pure oligonucleotides for exon 53 DMD therapy

Neuromuscular disorders : NMD, 2018-10, Vol.28, p.S67-S67

2018

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Novel approach to specific growth factor inhibition in vivo : Antagonism of platelet-derived growth factor in glomerulonephritis by aptamers

The American journal of pathology, 1999, Vol.154 (1), p.169-179

1999

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Efficient activation of nucleoside phosphoramidites with 4,5-dicyanoimidazole during oligonucleotide synthesis

Nucleic acids research, 1998-02, Vol.26 (4), p.1046

1998

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Potent 2'-Amino-2'-deoxypyrimidine RNA Inhibitors of Basic Fibroblast Growth Factor

Biochemistry (Easton), 1995-09, Vol.34 (36), p.11363-11372

1995

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978 Development of siRNA as a therapeutic for hepatitis C

Hepatology (Baltimore, Md.), 2003, Vol.38, p.627-627

2003

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Chemistry of L-ascorbic and D-isoascorbic acids. IV, an efficient synthesis of 2-deoxypentofuranoses

Journal of organic chemistry, 1990, Vol.55 (14), p.4400-4403

1990

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Chemistry of L-ascorbic and D-isoascorbic acids. 4. An efficient synthesis of 2-deoxypentofuranoses

Journal of organic chemistry, 1990-07, Vol.55 (14), p.4400-4403

1990

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Synthesis and Biological Evaluation of 1‘,2‘-Seconucleo-5‘-phosphonates

Journal of medicinal chemistry, 1996-03, Vol.39 (5), p.1130-1135

1996

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Diastereomeric 5,6-Dihydrothymidines. Preparation, Stereochemical Assignments, and MnO2 Oxidation Studies of Thymidines

Journal of organic chemistry, 1995-05, Vol.60 (10), p.3096-3099

1995

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Synthesis and biological evaluation of1',2'-seconucleo-5'- phosphonates

Journal of medicinal chemistry, 1996-03, Vol.39 (5), p.1130-1135

1996

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Adenosine Deaminase Inhibitors. Synthesis and Biological Evaluation of Putative Metabolites of (+)-erythro-9-(2S-Hydroxy-3R-nonyl)adenine

Journal of medicinal chemistry, 1994-10, Vol.37 (22), p.3844-3849

1994

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ChemInform Abstract: Chemistry of L-Ascorbic and D-Isoascorbic Acids. Part 4. An Efficient Synthesis of 2-Deoxypentofuranoses

ChemInform, 1991-03, Vol.22 (10), p.no-no

1991

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A Practical and Stereospecific Approach to the Synthesis of 3′-Deoxy-2′,3′-didehydrothymidine (D4T)

Nucleosides & nucleotides, 1992-09, Vol.11 (8), p.1549-1559

1992

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Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1

WVE-210201, an investigational stereopure oligonucleotide therapy for Duchenne muscular dystrophy, induces Exon 51 skipping and dystrophin protein restoration

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

Intimal hyperplasia recurs after removal of PDGF-AB and -BB inhibition in the rat carotid artery injury model

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

P.193 Phosphoryl guanidine-containing backbone modifications enhance exon skipping, dystrophin restoration and survival in a severe mouse model for DMD

THU-030 - Stereochemistry enhances pharmacological properties of APOC3 antisense oligonucleotides

Stereochemistry enhances pharmacological properties of APOC3 antisense oligonucleotides

Preclinical studies of WVE-210201, an investigational stereopure antisense oligonucleotide in development for the treatment of patients with duchenne muscular dystrophy (DMD)

P.402 - WVE-210201, an investigational stereopure oligonucleotide therapy for Duchenne muscular dystrophy, induces Exon 51 skipping and dystrophin protein restoration

Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA

DMD CLINICAL THERAPIES II

DMD CLINICAL THERAPIES II: P.127Identification of potent, muscle-targeting investigational stereo-pure oligonucleotides for exon 53 DMD therapy

Novel approach to specific growth factor inhibition in vivo : Antagonism of platelet-derived growth factor in glomerulonephritis by aptamers

Efficient activation of nucleoside phosphoramidites with 4,5-dicyanoimidazole during oligonucleotide synthesis

Potent 2'-Amino-2'-deoxypyrimidine RNA Inhibitors of Basic Fibroblast Growth Factor

978 Development of siRNA as a therapeutic for hepatitis C

Chemistry of L-ascorbic and D-isoascorbic acids. IV, an efficient synthesis of 2-deoxypentofuranoses

Chemistry of L-ascorbic and D-isoascorbic acids. 4. An efficient synthesis of 2-deoxypentofuranoses

Synthesis and Biological Evaluation of 1‘,2‘-Seconucleo-5‘-phosphonates

Diastereomeric 5,6-Dihydrothymidines. Preparation, Stereochemical Assignments, and MnO2 Oxidation Studies of Thymidines

Synthesis and biological evaluation of1',2'-seconucleo-5'- phosphonates

Adenosine Deaminase Inhibitors. Synthesis and Biological Evaluation of Putative Metabolites of (+)-erythro-9-(2S-Hydroxy-3R-nonyl)adenine

ChemInform Abstract: Chemistry of L-Ascorbic and D-Isoascorbic Acids. Part 4. An Efficient Synthesis of 2-Deoxypentofuranoses

A Practical and Stereospecific Approach to the Synthesis of 3′-Deoxy-2′,3′-didehydrothymidine (D4T)

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