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Harnessing multimodal data integration to advance precision oncology

Nature reviews. Cancer, 2022-02, Vol.22 (2), p.114-126

2022

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Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L)1 blockade in patients with non-small cell lung cancer

Nature cancer, 2022-10, Vol.3 (10), p.1151-1164

2022

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A curated and standardized adverse drug event resource to accelerate drug safety research

Scientific data, 2016-05, Vol.3 (1), p.160026, Article 160026

2016

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Disease Heritability Inferred from Familial Relationships Reported in Medical Records

Cell, 2018-06, Vol.173 (7), p.1692-1704.e11

2018

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Integration of peripheral blood- and tissue-based biomarkers of response to immune checkpoint blockade in urothelial carcinoma

The Journal of pathology, 2023-11, Vol.261 (3), p.349-360

2023

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Lung Microbial and Host Genomic Signatures as Predictors of Prognosis in Early-Stage Adenocarcinoma

Cancer epidemiology, biomarkers & prevention, 2024-09, p.OF1-OF12

2024

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Cross-platform dataset of multiplex fluorescent cellular object image annotations

Scientific data, 2023-04, Vol.10 (1), p.193-193, Article 193

2023

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3D Isotropic Super-resolution Prostate MRI Using Generative Adversarial Networks and Unpaired Multiplane Slices

Journal of digital imaging, 2021-10, Vol.34 (5), p.1199-1208

2021

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Tumor Immune Microenvironment and Response to Neoadjuvant Chemotherapy in Hormone Receptor/HER2+ Early Stage Breast Cancer

Clinical breast cancer, 2022-08, Vol.22 (6), p.538-546

2022

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Understanding the impact of chemotherapy on the immune landscape of high-grade serous ovarian cancer

Gynecologic oncology reports, 2022-02, Vol.39, p.100926-100926, Article 100926

2022

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Weakly Supervised Deep Learning Predicts Immunotherapy Response in Solid Tumors Based on PD-L1 Expression

Cancer research communications, 2024-01, Vol.4 (1), p.92-102

2024

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222-J Longitudinal spatial profiling of pediatric high-grade glioma reveals a heterogeneous and dynamic immune microenvironment with therapeutic implications

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 2), p.A1778-A1778

2023

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Multimodal data integration improves immunotherapy response prediction

Nature cancer, 2022-09, Vol.3 (10), p.1149-1150

2022

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Abstract PO5-15-12: Spatial immune correlates of response to eribulin and pembrolizumab in metastatic triple negative breast cancer (mTNBC) on the ENHANCE1 trial

Cancer research (Chicago, Ill.), 2024-05, Vol.84 (9_Supplement), p.PO5-15-12-PO5-15-12

2024

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Abstract P2-07-09: Characterization of the tumor microenvironment in patients with hormone receptor positive, HER2 negative early breast cancer

Cancer research (Chicago, Ill.), 2022-02, Vol.82 (4_Supplement), p.P2-P2-07-09

2022

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Ovarian cancer mutational processes drive site-specific immune evasion

Nature (London), 2022-12, Vol.612 (7941), p.778-786

2022

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Channel width optimized neural networks for liver and vessel segmentation in liver iron quantification

Computers in biology and medicine, 2020-07, Vol.122, p.103798-103798, Article 103798

2020

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Convolutional Neural Network Detection of Axillary Lymph Node Metastasis Using Standard Clinical Breast MRI

Clinical breast cancer, 2020-06, Vol.20 (3), p.e301-e308

2020

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Abstract P6-10-25: Characterization of the tumor immune microenvironment (TME) in early stage HR-positive HER2-positive breast cancer

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P6-P6-10-25

2020

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Segmentation of Brain Tumors Using DeepLabv3

Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, p.154-167

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Prediction of locally advanced rectal cancer response to neoadjuvant chemoradiation therapy using volumetric multiparametric MRI-based radiomics

Abdominal radiology (New York), 2024-03, Vol.49 (3), p.791-800

2024

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Abstract P3-09-17: Preoperative pembrolizumab increases sTILs in treatment naïve stage I/IIA TNBC patients in a window of opportunity trial

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P3-P3-09-17

2020

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Fast, light, and scalable: harnessing data-mined line annotations for automated tumor segmentation on brain MRI

European radiology, 2023-09, Vol.33 (9), p.6582-6591

2023

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Harnessing multimodal data integration to advance precision oncology

Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L)1 blockade in patients with non-small cell lung cancer

A curated and standardized adverse drug event resource to accelerate drug safety research

Disease Heritability Inferred from Familial Relationships Reported in Medical Records

Integration of peripheral blood- and tissue-based biomarkers of response to immune checkpoint blockade in urothelial carcinoma

Lung Microbial and Host Genomic Signatures as Predictors of Prognosis in Early-Stage Adenocarcinoma

Cross-platform dataset of multiplex fluorescent cellular object image annotations

3D Isotropic Super-resolution Prostate MRI Using Generative Adversarial Networks and Unpaired Multiplane Slices

Tumor Immune Microenvironment and Response to Neoadjuvant Chemotherapy in Hormone Receptor/HER2+ Early Stage Breast Cancer

Understanding the impact of chemotherapy on the immune landscape of high-grade serous ovarian cancer

Weakly Supervised Deep Learning Predicts Immunotherapy Response in Solid Tumors Based on PD-L1 Expression

222-J Longitudinal spatial profiling of pediatric high-grade glioma reveals a heterogeneous and dynamic immune microenvironment with therapeutic implications

Radiomics of MRI for pretreatment prediction of pathologic complete response, tumor regression grade, and neoadjuvant rectal score in patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation: an international multicenter study

Multimodal data integration improves immunotherapy response prediction

Abstract PO5-15-12: Spatial immune correlates of response to eribulin and pembrolizumab in metastatic triple negative breast cancer (mTNBC) on the ENHANCE1 trial

Abstract P2-07-09: Characterization of the tumor microenvironment in patients with hormone receptor positive, HER2 negative early breast cancer

Ovarian cancer mutational processes drive site-specific immune evasion

Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer

Channel width optimized neural networks for liver and vessel segmentation in liver iron quantification

Convolutional Neural Network Detection of Axillary Lymph Node Metastasis Using Standard Clinical Breast MRI

Abstract P6-10-25: Characterization of the tumor immune microenvironment (TME) in early stage HR-positive HER2-positive breast cancer

Segmentation of Brain Tumors Using DeepLabv3

Prediction of locally advanced rectal cancer response to neoadjuvant chemoradiation therapy using volumetric multiparametric MRI-based radiomics

Abstract P3-09-17: Preoperative pembrolizumab increases sTILs in treatment naïve stage I/IIA TNBC patients in a window of opportunity trial

Fast, light, and scalable: harnessing data-mined line annotations for automated tumor segmentation on brain MRI

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