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Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis

The Journal of experimental medicine, 1995-07, Vol.182 (1), p.75-85

1995

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CTLA-4: a negative regulator of autoimmune disease

The Journal of experimental medicine, 1996-08, Vol.184 (2), p.783-788

1996

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Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis

The Journal of clinical investigation, 2001-04, Vol.107 (8), p.995-1006

2001

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Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519

Journal of autoimmunity, 2000-05, Vol.14 (3), p.205-211

2000

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Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

Nature medicine, 1997-10, Vol.3 (10), p.1133-1136

1997

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Pathologic Role and Temporal Appearance of Newly Emerging Autoepitopes in Relapsing Experimental Autoimmune Encephalomyelitis

The Journal of immunology (1950), 2000-01, Vol.164 (2), p.670-678

2000

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Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis

The Journal of clinical investigation, 1999-01, Vol.103 (2), p.281-290

1999

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Differential Expression of Inflammatory Cytokines Parallels Progression of Central Nervous System Pathology in Two Clinically Distinct Models of Multiple Sclerosis

The Journal of immunology (1950), 1998-10, Vol.161 (8), p.4437-4446

1998

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The functional significance of epitope spreading and its regulation by co-stimulatory molecules

Immunological reviews, 1998-08, Vol.164 (1), p.63-72

1998

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Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

Immunity (Cambridge, Mass.), 1995-12, Vol.3 (6), p.739-745

1995

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Treatment with intact anti-B7-1 mAb during disease remission enhances epitope spreading and exacerbates relapses in R-EAE

Journal of neuroimmunology, 1997-11, Vol.79 (2), p.113-118

1997

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Temporal Development of Autoreactive Th1 Responses and Endogenous Presentation of Self Myelin Epitopes by Central Nervous System-Resident APCs in Theiler's Virus-Infected Mice

The Journal of immunology (1950), 2000-11, Vol.165 (9), p.5304-5314

2000

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Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

The Journal of clinical investigation, 1999-09, Vol.104 (5), p.599-610

1999

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Epitope spreading in immune-mediated diseases: implications for immunotherapy

Nature reviews. Immunology, 2002-02, Vol.2 (2), p.85-95

2002

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CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis

Journal of neuroimmunology, 2000-09, Vol.109 (2), p.173-180

2000

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Evolution of the T-Cell Repertoire during the Course of Experimental Immune-Mediated Demyelinating Diseases

Immunological reviews, 1995-04, Vol.144 (1), p.225-244

1995

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Virus-induced autoimmunity: Epitope spreading to myelin autoepitopes in theiler's virus infection of the central nervous system

Advances in Virus Research, 2001, Vol.56, p.199-217

2001

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Regulation of the Effector Stages of Experimental Autoimmune Encephalomyelitis via Neuroantigen-Specific Tolerance Induction. III. A Role for Anergy/Deletion

Autoimmunity (Chur, Switzerland), 1998, Vol.27 (1), p.13-28

1998

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Tissue-Specific Up-Regulation of B7-1 Expression and Function During the Course of Murine Relapsing Experimental Autoimmune Encephalomyelitis

The Journal of immunology (1950), 1998-07, Vol.161 (1), p.192-199

1998

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Characterization of and Functional Antigen Presentation by Central Nervous System Mononuclear Cells from Mice Infected with Theiler’s Murine Encephalomyelitis Virus

Journal of Virology, 1998-10, Vol.72 (10), p.7762-7771

1998

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Lymphocytes from mice chronically infected with Theiler’s murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. Epitope spreading in TMEV infection has functional activity

Journal of neuroimmunology, 2000-04, Vol.104 (1), p.79-84

2000

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Targeting the B7/CD28:CTLA-4 costimulatory system in CNS autoimmune disease

Journal of neuroimmunology, 1998-08, Vol.89 (1), p.10-18

1998

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CD8 + T cells from Theiler’s virus-resistant BALB/cByJ mice downregulate pathogenic virus-specific CD4 + T cells

Journal of neuroimmunology, 2000-07, Vol.106 (1), p.43-52

2000

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The role of protective CD8 + T cells in resistance of BALB/c mice to Theiler's murine encephalomyelitis virus-induced demyelinating disease: regulatory vs. lytic

Journal of neuroimmunology, 1999-08, Vol.98 (2), p.136-146

1999

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Epitope spreading leads to myelin-specific autoimmune responses in SJL mice chronically infected with Theiler's virus

Journal of neurovirology, 1997-05, Vol.3 Suppl 1, p.S62-S65

1997

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Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis

CTLA-4: a negative regulator of autoimmune disease

Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis

Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

Pathologic Role and Temporal Appearance of Newly Emerging Autoepitopes in Relapsing Experimental Autoimmune Encephalomyelitis

Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis

Differential Expression of Inflammatory Cytokines Parallels Progression of Central Nervous System Pathology in Two Clinically Distinct Models of Multiple Sclerosis

The functional significance of epitope spreading and its regulation by co-stimulatory molecules

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

Treatment with intact anti-B7-1 mAb during disease remission enhances epitope spreading and exacerbates relapses in R-EAE

Temporal Development of Autoreactive Th1 Responses and Endogenous Presentation of Self Myelin Epitopes by Central Nervous System-Resident APCs in Theiler's Virus-Infected Mice

Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

Epitope spreading in immune-mediated diseases: implications for immunotherapy

CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis

Evolution of the T-Cell Repertoire during the Course of Experimental Immune-Mediated Demyelinating Diseases

Virus-induced autoimmunity: Epitope spreading to myelin autoepitopes in theiler's virus infection of the central nervous system

Regulation of the Effector Stages of Experimental Autoimmune Encephalomyelitis via Neuroantigen-Specific Tolerance Induction. III. A Role for Anergy/Deletion

Tissue-Specific Up-Regulation of B7-1 Expression and Function During the Course of Murine Relapsing Experimental Autoimmune Encephalomyelitis

Characterization of and Functional Antigen Presentation by Central Nervous System Mononuclear Cells from Mice Infected with Theiler’s Murine Encephalomyelitis Virus

Lymphocytes from mice chronically infected with Theiler’s murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. Epitope spreading in TMEV infection has functional activity

Targeting the B7/CD28:CTLA-4 costimulatory system in CNS autoimmune disease

CD8 + T cells from Theiler’s virus-resistant BALB/cByJ mice downregulate pathogenic virus-specific CD4 + T cells

The role of protective CD8 + T cells in resistance of BALB/c mice to Theiler's murine encephalomyelitis virus-induced demyelinating disease: regulatory vs. lytic

Epitope spreading leads to myelin-specific autoimmune responses in SJL mice chronically infected with Theiler's virus

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