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Rapid determination of anticoagulating effects of dabigatran in whole blood with rotational thromboelastometry and a thrombin‐based trigger

Journal of thrombosis and haemostasis, 2018-12, Vol.16 (12), p.2462-2470

2018

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Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples

PloS one, 2019-08, Vol.14 (8), p.e0221407

2019

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Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model

Journal of thrombosis and haemostasis, 2012-09, Vol.10 (9), p.1841-1848

2012

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The addition of idarucizumab to plasma samples containing dabigatran allows the use of routine coagulation assays for the diagnosis of hemostasis disorders

Journal of thrombosis and haemostasis, 2015-11, Vol.13 (11), p.2087-2092

2015

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Efficacy of idarucizumab, prothrombin complex concentrate (PCC) and activated PCC to reverse the anticoagulatory potential of dabigatran in a porcine polytrauma model

Critical care (London, England), 2015-01, Vol.19 (S1), p.P351-P351, Article P351

2015

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In a trauma experimental pig model prothrombin complex concentrates and a specific antidote (idarucizumab) are effective to reverse the anticoagulant effects of dabigatran

Critical care (London, England), 2014-03, Vol.18 (2), p.P118-P118, Article P118

2014

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Inhibition of staphylothrombin by dabigatran reduces Staphylococcus aureus virulence

Journal of thrombosis and haemostasis, 2011-12, Vol.9 (12), p.2436-2446

2011

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Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity

Thrombosis and haemostasis, 2010-06, Vol.103 (6), p.1116-1127

2010

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Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4'-isomer

Inflammation research, 1998-06, Vol.47 (6), p.270-276

1998

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Prothrombin complex concentrate restores haemostasis in a dabigatran anticoagulated polytrauma pig model

Critical care (London, England), 2014-03, Vol.18 (2), p.P115-P115, Article P115

2014

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A specific antidote for dabigatran: functional and structural characterization

Blood, 2013-05, Vol.121 (18), p.3554-3562

2013

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Experimental models used to investigate the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 by non-steroidal anti-inflammatory drugs

Inflammation research, 1998-10, Vol.47 Suppl 2 (S2), p.S93-101

1998

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PO-82 Dabigatran etexilate blocks breast cancer progression in vitro and in a 4T1 breast cancer tumor model in mice

Thrombosis research, 2010, Vol.125, p.S188-S188

2010

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Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: resolving uncertainties in routine practice

Thrombosis and haemostasis, 2012-05, Vol.107 (5), p.838-847

2012

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Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E2 synthesis in rat microglial cells

Neuropharmacology, 2000-10, Vol.39 (11), p.2205-2213

2000

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Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E 2 synthesis in rat microglial cells

Neuropharmacology, 2000, Vol.39 (11), p.2205-2213

2000

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P3863Trauma victims requiring dabigatran reversal with idarucizumab in RE-VERSE AD

European heart journal, 2018-08, Vol.39 (suppl_1)

2018

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Clinical experience with cyclooxygenase-2 inhibitors

Inflammation research, 1999-05, Vol.48 (5), p.247-254

1999

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Fibrin formation by staphylothrombin facilitates Staphylococcus aureus-induced platelet aggregation

Thrombosis and haemostasis, 2012-06, Vol.107 (6), p.1107-1121

2012

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Dabigatran etexilate retards the initiation and progression of atherosclerotic lesions and inhibits the expression of oncostatin M in apolipoprotein E-deficient mice

Drug design, development and therapy, 2015-01, Vol.9 (default), p.5203-5211

2015

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A comparison of the thrombolytic and hemorrhagic effects of tissue-type plasminogen activator and streptokinase in rabbits

Circulation (New York, N.Y.), 1985-07, Vol.72 (1), p.178-182

1985

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Reversal of dabigatran clotting activity in the rat ex vivo by a specific and selective antibody fragment antidote: are there non-specific effects on warfarin, rivaroxaban and apixaban?

European heart journal, 2013-08, Vol.34 (suppl 1), p.P4848-P4848

2013

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Use of a specific antidote to dabigatran (idarucizumab) reduces blood loss and mortality in dabigatran-induced and trauma-induced bleeding in pigs

Critical care (London, England), 2014-03, Vol.18 (2), p.P99-P99, Article P99

2014

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Selective cyclooxygenase-2 inhibitors: pharmacology, clinical effects and therapeutic potential

Expert opinion on investigational drugs, 1997-05, Vol.6 (5), p.609-614

1997

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COX-2 selectivity and inflammatory processes

Current medicinal chemistry, 2000-11, Vol.7 (11), p.1145-1161

2000

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Rapid determination of anticoagulating effects of dabigatran in whole blood with rotational thromboelastometry and a thrombin‐based trigger

Scalable, semi-automated fluorescence reduction neutralization assay for qualitative assessment of Ebola virus-neutralizing antibodies in human clinical samples

Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model

The addition of idarucizumab to plasma samples containing dabigatran allows the use of routine coagulation assays for the diagnosis of hemostasis disorders

Efficacy of idarucizumab, prothrombin complex concentrate (PCC) and activated PCC to reverse the anticoagulatory potential of dabigatran in a porcine polytrauma model

In a trauma experimental pig model prothrombin complex concentrates and a specific antidote (idarucizumab) are effective to reverse the anticoagulant effects of dabigatran

Inhibition of staphylothrombin by dabigatran reduces Staphylococcus aureus virulence

Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity

Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4'-isomer

Prothrombin complex concentrate restores haemostasis in a dabigatran anticoagulated polytrauma pig model

A specific antidote for dabigatran: functional and structural characterization

Experimental models used to investigate the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 by non-steroidal anti-inflammatory drugs

PO-82 Dabigatran etexilate blocks breast cancer progression in vitro and in a 4T1 breast cancer tumor model in mice

Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: resolving uncertainties in routine practice

Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E2 synthesis in rat microglial cells

Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E 2 synthesis in rat microglial cells

P3863Trauma victims requiring dabigatran reversal with idarucizumab in RE-VERSE AD

Clinical experience with cyclooxygenase-2 inhibitors

Fibrin formation by staphylothrombin facilitates Staphylococcus aureus-induced platelet aggregation

Dabigatran etexilate retards the initiation and progression of atherosclerotic lesions and inhibits the expression of oncostatin M in apolipoprotein E-deficient mice

A comparison of the thrombolytic and hemorrhagic effects of tissue-type plasminogen activator and streptokinase in rabbits

Reversal of dabigatran clotting activity in the rat ex vivo by a specific and selective antibody fragment antidote: are there non-specific effects on warfarin, rivaroxaban and apixaban?

Use of a specific antidote to dabigatran (idarucizumab) reduces blood loss and mortality in dabigatran-induced and trauma-induced bleeding in pigs

Selective cyclooxygenase-2 inhibitors: pharmacology, clinical effects and therapeutic potential

COX-2 selectivity and inflammatory processes

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