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Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

Angewandte Chemie International Edition, 2012-11, Vol.51 (46), p.11463-11467

2012

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Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives

Nature communications, 2022-01, Vol.13 (1), p.171-171, Article 171

2022

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Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Journal of medicinal chemistry, 2018-08, Vol.61 (16), p.7387-7393

2018

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Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

Science (American Association for the Advancement of Science), 2019-01, Vol.363 (6423)

2019

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Sulfenome mining in Arabidopsis thaliana

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.11545-11550

2014

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Redox‐regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H‐site flexibility

Protein science, 2019-01, Vol.28 (1), p.56-67

2019

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Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids

Nature communications, 2024-02, Vol.15 (1), p.1779-1779, Article 1779

2024

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Structure of the Prx6‐subfamily 1‐Cys peroxiredoxin from Sulfolobus islandicus

Acta crystallographica. Section F, Structural biology communications, 2019-06, Vol.75 (6), p.428-434

2019

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Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection

Frontiers in immunology, 2019-12, Vol.10, p.2920

2019

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The active site architecture in peroxiredoxins: a case study on Mycobacterium tuberculosis AhpE

Chemical communications (Cambridge, England), 2016-01, Vol.52 (67), p.10293-10296

2016

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Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

Chemistry & biology, 2012-10, Vol.19 (10), p.1300-1312

2012

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Chaperoning Anfinsen: the steric foldases

Molecular microbiology, 2007-05, Vol.64 (4), p.917-922

2007

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Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

Journal of medicinal chemistry, 2014-10, Vol.57 (20), p.8657-8663

2014

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Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

Journal of the American Chemical Society, 2012-03, Vol.134 (10), p.4465-4468

2012

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Chloroplasts Assemble the Major Subunit FaeG of Escherichia coli F4 (K88) Fimbriae to Strand-swapped Dimers

Journal of molecular biology, 2007-05, Vol.368 (3), p.791-799

2007

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How Thioredoxin can Reduce a Buried Disulphide Bond

Journal of molecular biology, 2004-06, Vol.339 (3), p.527-537

2004

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Functional and structural characterization of Hypocrates, a genetically encoded biosensor for hypochlorite

Free radical biology & medicine, 2021-12, Vol.177, p.S94-S95

2021

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Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage

Biochimica et biophysica acta. General subjects, 2018-03, Vol.1862 (3), p.775-789

2018

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An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus

The Journal of biological chemistry, 2018-03, Vol.293 (10), p.3839-3848

2018

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Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction

Antiviral research, 2023-09, Vol.217, p.105675-105675, Article 105675

2023

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The Corynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species‐scavenging enzyme that shows promiscuity in thiol redox control

Molecular microbiology, 2015-06, Vol.96 (6), p.1176-1191

2015

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Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases

Biochemistry (Easton), 2013-08, Vol.52 (31), p.5236-5246

2013

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Corynebacterium diphtheriae Methionine Sulfoxide Reductase A Exploits a Unique Mycothiol Redox Relay Mechanism

The Journal of biological chemistry, 2015-05, Vol.290 (18), p.11365-11375

2015

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Sulfur denitrosylation by an engineered Trx-like DsbG enzyme identifies nucleophilic cysteine hydrogen bonds as key functional determinant

The Journal of biological chemistry, 2017-11, Vol.292 (46), p.18831-18831

2017

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Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

Science (American Association for the Advancement of Science), 2019-01, Vol.363 (6423)

2019

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Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives

Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase

Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission

Sulfenome mining in Arabidopsis thaliana

Redox‐regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H‐site flexibility

Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids

Structure of the Prx6‐subfamily 1‐Cys peroxiredoxin from Sulfolobus islandicus

Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection

The active site architecture in peroxiredoxins: a case study on Mycobacterium tuberculosis AhpE

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

Chaperoning Anfinsen: the steric foldases

Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

Chloroplasts Assemble the Major Subunit FaeG of Escherichia coli F4 (K88) Fimbriae to Strand-swapped Dimers

How Thioredoxin can Reduce a Buried Disulphide Bond

Functional and structural characterization of Hypocrates, a genetically encoded biosensor for hypochlorite

Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage

An essential thioredoxin is involved in the control of the cell cycle in the bacterium Caulobacter crescentus

Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction

The Corynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species‐scavenging enzyme that shows promiscuity in thiol redox control

Multimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin Ligases

Corynebacterium diphtheriae Methionine Sulfoxide Reductase A Exploits a Unique Mycothiol Redox Relay Mechanism

Sulfur denitrosylation by an engineered Trx-like DsbG enzyme identifies nucleophilic cysteine hydrogen bonds as key functional determinant

Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

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