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Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease

Journal of immunology research, 2018-01, Vol.2018, p.4784268-12

2018

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The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies

Acta neuropathologica, 2020-06, Vol.139 (6), p.977-1000

2020

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Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration

Frontiers in immunology, 2019-01, Vol.10, p.80-80

2019

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LRRK2 Ablation Attenuates Αlpha-Synuclein–Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo

Neurotherapeutics, 2021-04, Vol.18 (2), p.949-961

2021

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Increased P2X7 Receptor Binding Is Associated With Neuroinflammation in Acute but Not Chronic Rodent Models for Parkinson's Disease

Frontiers in neuroscience, 2019-07, Vol.13, p.799-799

2019

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Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson's disease

Acta neuropathologica communications, 2019-10, Vol.7 (1), p.160-160, Article 160

2019

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Parkin Protects against Neurotoxicity in the 6-Hydroxydopamine Rat Model for Parkinson's Disease

Molecular therapy, 2006-11, Vol.14 (5), p.716-723

2006

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α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

Nature (London), 2015-06, Vol.522 (7556), p.340-344

2015

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Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated Î±-synuclein

Frontiers in behavioral neuroscience, 2015-03, Vol.9

2015

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Altered mGluR5 binding potential and glutamine concentration in the 6-OHDA rat model of acute Parkinson's disease and levodopa-induced dyskinesia

Neurobiology of aging, 2018-01, Vol.61, p.82-92

2018

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rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

Molecular neurodegeneration, 2013-11, Vol.8 (1), p.44-44, Article 44

2013

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Host oligodendrogliopathy and α-synuclein strains dictate disease severity in multiple system atrophy

Brain (London, England : 1878), 2023-01, Vol.146 (1), p.237-251

2023

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Rab7 reduces α-synuclein toxicity in rats and primary neurons

Experimental neurology, 2022-01, Vol.347, p.113900-113900, Article 113900

2022

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Identifying a glucose metabolic brain pattern in an adeno-associated viral vector based rat model for Parkinson’s disease using 18F-FDG PET imaging

Scientific reports, 2019-08, Vol.9 (1), p.1-8, Article 12368

2019

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Temporal changes in neuroinflammation and brain glucose metabolism in a rat model of viral vector-induced α-synucleinopathy

Experimental neurology, 2019-10, Vol.320, p.112964-112964, Article 112964

2019

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Host oligodendrogliopathy and ɑ-synuclein strains dictate disease severity in multiple system atrophy

Brain (London, England : 1878), 2023, Vol.146 (1), p.237

2023

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Viral vector-based models of Parkinson's disease

Current topics in behavioral neurosciences, 2015-01, Vol.22, p.271

2015

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The structural differences between patient-derived [alpha]-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies

Acta neuropathologica, 2020-06, Vol.139 (6), p.977

2020

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Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

Neurobiology of aging, 2015-03, Vol.36 (3), p.1543-1558

2015

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Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration

Journal of neuropathology and experimental neurology, 2014-02, Vol.73 (2), p.159-174

2014

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FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an α-synuclein-based rat model for Parkinson's disease

Neurobiology of aging, 2015-03, Vol.36 (3), p.1559-1568

2015

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Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation

Scientific reports, 2018-04, Vol.8 (1), p.1-10, Article 6580

2018

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Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice

Neurobiology of aging, 2014-11, Vol.35 (11), p.2625-2636

2014

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The role of LRRK2 inhibition in α-synuclein-induced neurotoxicity and neuroinflammation in vivo

Frontiers in neuroscience, 2019, Vol.13

2019

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NEURONAL ACTIVITY MODULATION IN AN ALPHA-SYNUCLEIN-BASED RAT MODEL FOR PARKINSON’S DISEASE

Frontiers in neuroscience, 2019, Vol.13

2019

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Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease

The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies

Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration

LRRK2 Ablation Attenuates Αlpha-Synuclein–Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo

Increased P2X7 Receptor Binding Is Associated With Neuroinflammation in Acute but Not Chronic Rodent Models for Parkinson's Disease

Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson's disease

Parkin Protects against Neurotoxicity in the 6-Hydroxydopamine Rat Model for Parkinson's Disease

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

Nigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated Î±-synuclein

Altered mGluR5 binding potential and glutamine concentration in the 6-OHDA rat model of acute Parkinson's disease and levodopa-induced dyskinesia

rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration

Host oligodendrogliopathy and α-synuclein strains dictate disease severity in multiple system atrophy

Rab7 reduces α-synuclein toxicity in rats and primary neurons

Identifying a glucose metabolic brain pattern in an adeno-associated viral vector based rat model for Parkinson’s disease using 18F-FDG PET imaging

Temporal changes in neuroinflammation and brain glucose metabolism in a rat model of viral vector-induced α-synucleinopathy

Host oligodendrogliopathy and ɑ-synuclein strains dictate disease severity in multiple system atrophy

Viral vector-based models of Parkinson's disease

The structural differences between patient-derived [alpha]-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration

FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an α-synuclein-based rat model for Parkinson's disease

Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation

Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice

The role of LRRK2 inhibition in α-synuclein-induced neurotoxicity and neuroinflammation in vivo

NEURONAL ACTIVITY MODULATION IN AN ALPHA-SYNUCLEIN-BASED RAT MODEL FOR PARKINSON’S DISEASE

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