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Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications

2023

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Impaired vascular β-adrenergic relaxation in spontaneously hypertensive rats: The differences between conduit and resistance arteries

European journal of pharmacology, 2023-11, Vol.958, p.176045-176045, Article 176045

2023

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Changes in cardiovascular autonomic control induced by chronic inhibition of acetylcholinesterase during pyridostigmine or donepezil treatment of spontaneously hypertensive rats

European journal of pharmacology, 2024-05, Vol.971, p.176526-176526, Article 176526

2024

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Nitric oxide and salt resistance in Dahl rats: no role of inducible NO synthase

Physiological research, 2023, Vol.72 (1), p.123-127

2023

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Hypertension after the Menopause: What Can We Learn from Experimental Studies?

Physiological research, 2023, Vol.72, p.S91-S112

2023

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More efficient adaptation of cardiovascular response to repeated restraint in spontaneously hypertensive rats: the role of autonomic nervous system

Hypertension research, 2024-07

2024

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Hemodynamic Response to Gabapentin in Conscious Spontaneously Hypertensive Rats: The Role of Sympathetic Nervous System

Hypertension (Dallas, Tex. 1979), 2018-09, Vol.72 (3), p.676-685

2018

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Chronic inhibition of angiotensin converting enzyme lowers blood pressure in spontaneously hypertensive rats by attenuation of sympathetic tone: The role of enhanced baroreflex sensitivity

Biomedicine & pharmacotherapy, 2024-07, Vol.176, p.116796, Article 116796

2024

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Basal and Activated Calcium Sensitization Mediated by RhoA/Rho Kinase Pathway in Rats with Genetic and Salt Hypertension

BioMed research international, 2017-01, Vol.2017, p.8029728-13

2017

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The abnormalities of adrenomedullary hormonal system in genetic hypertension: Their contribution to altered regulation of blood pressure

Physiological research, 2021-07, Vol.70 (3), p.307-326

2021

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Contribution of selected vasoactive systems to blood pressure regulation in two models of chronic kidney disease

Physiological research, 2020-07, Vol.69 (3), p.405-414

2020

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Moderate additive effects of endothelin receptor A blockade in Ren-2 transgenic rats subjected to various types of RAS blockade

Life sciences (1973), 2016-08, Vol.159, p.127-134

2016

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The Fifteenth International Conference on Endothelin (ET-15), Prague, Czech Republic, 2017

Physiological research, 2018-01, Vol.67, p.S1-S3

2018

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Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet

Journal of hypertension, 2015-01, Vol.33 (1), p.161-169

2015

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Obesity-related hypertension: possible pathophysiological mechanisms

Journal of endocrinology, 2014-12, Vol.223 (3), p.R63-R78

2014

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The effects of repeated delivery of angiotensin II AT(1) receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals

Hypertension research, 2012-07, Vol.35 (7), p.761-768

2012

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Cooperation of augmented calcium sensitization and increased calcium entry contributes to high blood pressure in salt-sensitive Dahl rats

Hypertension research, 2021-09, Vol.44 (9), p.1067-1078

2021

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In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia

International journal of molecular sciences, 2021-10, Vol.22 (21), p.11513

2021

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Which sympathoadrenal abnormalities of adult spontaneously hypertensive rats can be traced to a prehypertensive stage?

Hypertension research, 2019-07, Vol.42 (7), p.949-959

2019

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Endothelin type A receptor blockade increases renoprotection in congestive heart failure combined with chronic kidney disease: Studies in 5/6 nephrectomized rats with aorto-caval fistula

Biomedicine & pharmacotherapy, 2023-02, Vol.158, p.114157-114157, Article 114157

2023

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Antihypertensive and metabolic effects of empagliflozin in Ren-2 transgenic rats, an experimental non-diabetic model of hypertension

Biomedicine & pharmacotherapy, 2021-12, Vol.144, p.112246-112246, Article 112246

2021

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Hepatoprotective and cardioprotective effects of empagliflozin in spontaneously hypertensive rats fed a high-fat diet

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116520-116520, Article 116520

2024

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Both central sympathoexcitation and peripheral angiotensin II-dependent vasoconstriction contribute to hypertension development in immature heterozygous Ren-2 transgenic rats

Hypertension research, 2022-03, Vol.45 (3), p.414-423

2022

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Sympathectomy-induced blood pressure reduction in adult normotensive and hypertensive rats is counteracted by enhanced cardiovascular sensitivity to vasoconstrictors

Hypertension research, 2019-12, Vol.42 (12), p.1872-1882

2019

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Role of angiotensin II in chronic blood pressure control of heterozygous Ren-2 transgenic rats: Peripheral vasoconstriction versus central sympathoexcitation

Biomedicine & pharmacotherapy, 2019-08, Vol.116, p.108996-108996, Article 108996

2019

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Animal Models for Study of Pathophysiological Mechanisms of Hypertension and Its Complications

Impaired vascular β-adrenergic relaxation in spontaneously hypertensive rats: The differences between conduit and resistance arteries

Changes in cardiovascular autonomic control induced by chronic inhibition of acetylcholinesterase during pyridostigmine or donepezil treatment of spontaneously hypertensive rats

Nitric oxide and salt resistance in Dahl rats: no role of inducible NO synthase

Hypertension after the Menopause: What Can We Learn from Experimental Studies?

More efficient adaptation of cardiovascular response to repeated restraint in spontaneously hypertensive rats: the role of autonomic nervous system

Hemodynamic Response to Gabapentin in Conscious Spontaneously Hypertensive Rats: The Role of Sympathetic Nervous System

Chronic inhibition of angiotensin converting enzyme lowers blood pressure in spontaneously hypertensive rats by attenuation of sympathetic tone: The role of enhanced baroreflex sensitivity

Basal and Activated Calcium Sensitization Mediated by RhoA/Rho Kinase Pathway in Rats with Genetic and Salt Hypertension

The abnormalities of adrenomedullary hormonal system in genetic hypertension: Their contribution to altered regulation of blood pressure

Contribution of selected vasoactive systems to blood pressure regulation in two models of chronic kidney disease

Moderate additive effects of endothelin receptor A blockade in Ren-2 transgenic rats subjected to various types of RAS blockade

The Fifteenth International Conference on Endothelin (ET-15), Prague, Czech Republic, 2017

Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet

Obesity-related hypertension: possible pathophysiological mechanisms

The effects of repeated delivery of angiotensin II AT(1) receptor antisense on distinct vasoactive systems in Ren-2 transgenic rats: young vs. adult animals

Cooperation of augmented calcium sensitization and increased calcium entry contributes to high blood pressure in salt-sensitive Dahl rats

In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia

Which sympathoadrenal abnormalities of adult spontaneously hypertensive rats can be traced to a prehypertensive stage?

Endothelin type A receptor blockade increases renoprotection in congestive heart failure combined with chronic kidney disease: Studies in 5/6 nephrectomized rats with aorto-caval fistula

Antihypertensive and metabolic effects of empagliflozin in Ren-2 transgenic rats, an experimental non-diabetic model of hypertension

Hepatoprotective and cardioprotective effects of empagliflozin in spontaneously hypertensive rats fed a high-fat diet

Both central sympathoexcitation and peripheral angiotensin II-dependent vasoconstriction contribute to hypertension development in immature heterozygous Ren-2 transgenic rats

Sympathectomy-induced blood pressure reduction in adult normotensive and hypertensive rats is counteracted by enhanced cardiovascular sensitivity to vasoconstrictors

Role of angiotensin II in chronic blood pressure control of heterozygous Ren-2 transgenic rats: Peripheral vasoconstriction versus central sympathoexcitation

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