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Instantaneous ion configurations in the K⁺ ion channel selectivity filter revealed by 2D IR spectroscopy

Science (American Association for the Advancement of Science), 2016-09, Vol.353 (6303), p.1040-1044

2016

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Individual Ion Binding Sites in the K+ Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation

Structure (London), 2016-05, Vol.24 (5), p.750-761

2016

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Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy

Journal of the American Chemical Society, 2017-07, Vol.139 (26), p.8837-8845

2017

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Semisynthetic K⁺ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (39), p.15698-15703

2013

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Ion-binding properties of a K⁺ channel selectivity filter in different conformations

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (49), p.15096-15100

2015

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Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor

Nature communications, 2018-11, Vol.9 (1), p.5055-10, Article 5055

2018

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Ion Selectivity in a Semisynthetic K⁺ Channel Locked in the Conductive Conformation

Science (American Association for the Advancement of Science), 2006-11, Vol.314 (5801), p.1004-1007

2006

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Lipids in the Structure, Folding, and Function of the KcsA K+ Channel

Biochemistry (Easton), 2002-09, Vol.41 (35), p.10771-10777

2002

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Using protein backbone mutagenesis to dissect the link between ion occupancy and C-type inactivation in K⁺ channels

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17886-17891

2013

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A facile approach for the in vitro assembly of multimeric membrane transport proteins

eLife, 2018-06, Vol.7

2018

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A glimpse into the C-type-inactivated state for a Potassium Channel

Nature structural & molecular biology, 2017-10, Vol.24 (10), p.787

Valiyaveetil, Francis I

2017

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A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105517-105517, Article 105517

2024

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Distinct roles of the Na + binding sites in the allosteric coupling mechanism of the glutamate transporter homolog, Glt Ph

Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (19), p.e2121653119

2022

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Distinct roles of the Na+ binding sites in the allosteric coupling mechanism of the glutamate transporter homolog, GltPh

Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (19), p.1-e2121653119

2022

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Investigation of the allosteric coupling mechanism in a glutamate transporter homolog via unnatural amino acid mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (32), p.15939-15946

2019

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Glycine as a D-Amino Acid Surrogate in the K+-Selectivity Filter

Proceedings of the National Academy of Sciences - PNAS, 2004-12, Vol.101 (49), p.17045-17049

2004

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Structures of Gating Intermediates in a K+ channel

Journal of molecular biology, 2021-11, Vol.433 (23), p.167296-167296, Article 167296

2021

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Probing Ion Configurations in the KcsA Selectivity Filter with Single-Isotope Labels and 2D IR Spectroscopy

Journal of the American Chemical Society, 2023-08, Vol.145 (33), p.18529-18537

2023

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Water inside the Selectivity Filter of a K+ Ion Channel: Structural Heterogeneity, Picosecond Dynamics, and Hydrogen Bonding

Journal of the American Chemical Society, 2024-01, Vol.146 (2), p.1543-1553

2024

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Patch-Clamp Recordings of the KcsA K + Channel in Unilamellar Blisters

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1684, p.181

2018

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Combining in Vitro Folding with Cell Free Protein Synthesis for Membrane Protein Expression

Biochemistry (Easton), 2016-08, Vol.55 (30), p.4212-4219

2016

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A Shared Mechanism for the Folding of Voltage-Gated K+ Channels

Biochemistry (Easton), 2019-03, Vol.58 (12), p.1660-1671

2019

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Structural basis for C-type inactivation in a Shaker family voltage-gated K + channel

Science advances, 2022-04, Vol.8 (16), p.eabm8804-eabm8804

2022

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Engineering the Glutamate Transporter Homologue GltPh Using Protein Semisynthesis

Biochemistry (Easton), 2015-03, Vol.54 (8), p.1694-1702

2015

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Semisynthesis and Folding of the Potassium Channel KcsA

Journal of the American Chemical Society, 2002-08, Vol.124 (31), p.9113-9120

2002

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Instantaneous ion configurations in the K⁺ ion channel selectivity filter revealed by 2D IR spectroscopy

Individual Ion Binding Sites in the K+ Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation

Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy

Semisynthetic K⁺ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state

Ion-binding properties of a K⁺ channel selectivity filter in different conformations

Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor

Ion Selectivity in a Semisynthetic K⁺ Channel Locked in the Conductive Conformation

Lipids in the Structure, Folding, and Function of the KcsA K+ Channel

Using protein backbone mutagenesis to dissect the link between ion occupancy and C-type inactivation in K⁺ channels

A facile approach for the in vitro assembly of multimeric membrane transport proteins

A glimpse into the C-type-inactivated state for a Potassium Channel

A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds

Distinct roles of the Na + binding sites in the allosteric coupling mechanism of the glutamate transporter homolog, Glt Ph

Distinct roles of the Na+ binding sites in the allosteric coupling mechanism of the glutamate transporter homolog, GltPh

Investigation of the allosteric coupling mechanism in a glutamate transporter homolog via unnatural amino acid mutagenesis

Glycine as a D-Amino Acid Surrogate in the K+-Selectivity Filter

Structures of Gating Intermediates in a K+ channel

Probing Ion Configurations in the KcsA Selectivity Filter with Single-Isotope Labels and 2D IR Spectroscopy

Water inside the Selectivity Filter of a K+ Ion Channel: Structural Heterogeneity, Picosecond Dynamics, and Hydrogen Bonding

Patch-Clamp Recordings of the KcsA K + Channel in Unilamellar Blisters

Combining in Vitro Folding with Cell Free Protein Synthesis for Membrane Protein Expression

A Shared Mechanism for the Folding of Voltage-Gated K+ Channels

Structural basis for C-type inactivation in a Shaker family voltage-gated K + channel

Engineering the Glutamate Transporter Homologue GltPh Using Protein Semisynthesis

Semisynthesis and Folding of the Potassium Channel KcsA

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