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Six Years (2012–2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2‐Pyridone Compounds

Chemical record, 2018-12, Vol.18 (12), p.1818-1832

2018

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Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

Clinical epigenetics, 2017-05, Vol.9 (1), p.59-59, Article 59

2017

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Polycomb Repressive Complex 2 Modulation through the Development of EZH2–EED Interaction Inhibitors and EED Binders

Journal of medicinal chemistry, 2021-08, Vol.64 (16), p.11774-11797

2021

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Aptian flood basalts in Bacalhau oil and gas field: petrogenesis and geodynamics of post-rift tholeiites in the pre-salt sequence of Santos Basin, Brazil

Contributions to mineralogy and petrology, 2023-03, Vol.178 (3), p.15, Article 15

2023

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The Innovative Potential of Statins in Cancer: New Targets for New Therapies

Frontiers in chemistry, 2020-06, Vol.8, p.516-516

2020

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DNA Methyltransferases Inhibitors from Natural Sources

Current topics in medicinal chemistry, 2016-01, Vol.16 (7), p.680

2016

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EZH2 inhibitors: a patent review (2014-2016)

Expert opinion on therapeutic patents, 2017-07, Vol.27 (7), p.797-813

2017

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Oxidative stress and epigenetic regulation in ageing and age-related diseases

International Journal of Molecular Sciences, 2013-08, Vol.14 (9), p.17643-17663

2013

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LSD1 inhibitors: a patent review (2010-2015)

Expert opinion on therapeutic patents, 2016-05, Vol.26 (5), p.565-580

2016

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Emerging approaches for histone deacetylase inhibitor drug discovery

Expert opinion on drug discovery, 2015-06, Vol.10 (6), p.599-613

2015

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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Diabetes (New York, N.Y.), 2013-03, Vol.62 (3), p.732-742

2013

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1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

Journal of medicinal chemistry, 2014-07, Vol.57 (14), p.6259-6265

2014

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The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells

Scientific reports, 2019-11, Vol.9 (1), p.15925-13, Article 15925

2019

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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression

Gastroenterology (New York, N.Y. 1943), 2021-11, Vol.161 (5), p.1584-1600

2021

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Novel Histone Deacetylase Inhibitors Induce Growth Arrest, Apoptosis, and Differentiation in Sarcoma Cancer Stem Cells

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.4073-4079

2015

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A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

Redox biology, 2020-05, Vol.32, p.101466-101466, Article 101466

2020

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Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

Journal of the American Chemical Society, 2010-05, Vol.132 (19), p.6827-6833

2010

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Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (9), p.2752-2757

2015

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Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent

Journal of medicinal chemistry, 2016-02, Vol.59 (4), p.1501-1517

2016

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Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy

Nature communications, 2024-03, Vol.15 (1), p.2235-2235, Article 2235

2024

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Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.701-713

2014

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Altered modulation of lamin A/C‐HDAC2 interaction and p21 expression during oxidative stress response in HGPS

Aging cell, 2018-10, Vol.17 (5), p.e12824-n/a

2018

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CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas

Frontiers in pharmacology, 2020-08, Vol.11, p.1230-1230

2020

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Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells

Cell death & disease, 2022-11, Vol.13 (11), p.965-965, Article 965

2022

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Editorial: Natural Product Epigenetic Modulators and Inhibitors

Frontiers in pharmacology, 2021-03, Vol.12, p.651395-651395

2021

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Six Years (2012–2018) of Researches on Catalytic EZH2 Inhibitors: The Boom of the 2‐Pyridone Compounds

Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

Polycomb Repressive Complex 2 Modulation through the Development of EZH2–EED Interaction Inhibitors and EED Binders

Aptian flood basalts in Bacalhau oil and gas field: petrogenesis and geodynamics of post-rift tholeiites in the pre-salt sequence of Santos Basin, Brazil

The Innovative Potential of Statins in Cancer: New Targets for New Therapies

DNA Methyltransferases Inhibitors from Natural Sources

EZH2 inhibitors: a patent review (2014-2016)

Oxidative stress and epigenetic regulation in ageing and age-related diseases

LSD1 inhibitors: a patent review (2010-2015)

Emerging approaches for histone deacetylase inhibitor drug discovery

Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

1,3,4-Oxadiazole-Containing Histone Deacetylase Inhibitors: Anticancer Activities in Cancer Cells

The Protein Arginine Methyltransferases 1 and 5 affect Myc properties in glioblastoma stem cells

Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression

Novel Histone Deacetylase Inhibitors Induce Growth Arrest, Apoptosis, and Differentiation in Sarcoma Cancer Stem Cells

A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases LSD1 and LSD2

Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent

Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy

Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells

Altered modulation of lamin A/C‐HDAC2 interaction and p21 expression during oxidative stress response in HGPS

CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas

Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells

Editorial: Natural Product Epigenetic Modulators and Inhibitors

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