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Structural biology of factor VIIa/tissue factor initiated coagulation

Frontiers in bioscience (Landmark. Print), 2012-06, Vol.17 (7), p.2476-2494

2012

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An estimate of the numbers and density of low-energy structures (or decoys) in the conformational landscape of proteins

PloS one, 2009-04, Vol.4 (4), p.e5148-e5148

2009

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Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1

Journal of clinical medicine, 2020-11, Vol.9 (11), p.3684

2020

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P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Alzheimer's & dementia, 2019-07, Vol.15, p.P1294-P1295

2019

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Plasmin‐mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

Journal of thrombosis and haemostasis, 2020-05, Vol.18 (5), p.1171-1182

2020

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Evaluation of an Allosteric BACE Inhibitor Peptide to Identify Mimetics that Can Interact with the Loop F Region of the Enzyme and Prevent APP Cleavage

Journal of molecular biology, 2018-05, Vol.430 (11), p.1566-1576

2018

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Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair

Annals of the rheumatic diseases, 2018-05, Vol.77 (5), p.760

2018

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Structure of human factor VIIa–soluble tissue factor with calcium, magnesium and rubidium

Acta crystallographica. Section D, Biological crystallography., 2021-06, Vol.77 (6), p.809-819

2021

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Sodium‐site in serine protease domain of human coagulation factor IXa: evidence from the crystal structure and molecular dynamics simulations study

Journal of thrombosis and haemostasis, 2019-04, Vol.17 (4), p.574-584

2019

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Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2

Biochemical and biophysical research communications, 2018-05, Vol.499 (4), p.751-757

2018

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Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis

Science translational medicine, 2023-03, Vol.15 (688), p.eabq2395

2023

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Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease

ACS chemical biology, 2020-06, Vol.15 (6), p.1671-1684

2020

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An Estimate of the Numbers and Density of Low-Energy Structures

PloS one, 2009-04, Vol.4 (4), p.e5148

2009

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Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimerșs Disease

ACS chemical biology, 2020-05, Vol.15 (6), p.1671-1684

2020

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A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity

ACS chemical neuroscience, 2018-03, Vol.9 (3), p.462-468

2018

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PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P1294-P1295

2019

Volltextzugriff (PDF)

P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_25)

2019

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Structural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium

Journal of molecular biology, 2013-06, Vol.425 (11), p.1961-1981

2013

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Quantifying Vitamin K-dependent Holoprotein Compaction caused by differential γ-carboxylation using HPSEC

Analytical biochemistry, 2015-03, Vol.479, p.6-14

2015

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Does Protease Domain of Human Factor IXa Contain a Sodium Site? Evidence From the 1.64 Å Resolution Crystal Structure

Blood, 2011-11, Vol.118 (21), p.2246-2246

2011

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Platelets Contain Tissue Factor Pathway Inhibitor-2 Derived from Megakaryocytes and Inhibits Fibrinolysis

The Journal of biological chemistry, 2014-11, Vol.289 (45), p.31647-31661

2014

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Engineering Kunitz Domain 1 (KD1) of Human Tissue Factor Pathway Inhibitor-2 to Selectively Inhibit Fibrinolysis: PROPERTIES OF KD1-L17R VARIANT

The Journal of biological chemistry, 2011-02, Vol.286 (6), p.4329-4340

2011

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Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography

Analytical biochemistry, 2015-06, Vol.479, p.6-14

2015

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Structural and Functional Studies of I3-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium

Journal of molecular biology, 2013-06, Vol.425 (11), p.1961-1981

2013

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Epitope Mapping of a Monoclonal Antibody to Factor VIII That Inhibits Factor IXa:Factor VIIIa Interaction and Thrombin Activation of Factor VIII

Blood, 2011-11, Vol.118 (21), p.1177-1177

2011

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Structural biology of factor VIIa/tissue factor initiated coagulation

An estimate of the numbers and density of low-energy structures (or decoys) in the conformational landscape of proteins

Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1

P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Plasmin‐mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

Evaluation of an Allosteric BACE Inhibitor Peptide to Identify Mimetics that Can Interact with the Loop F Region of the Enzyme and Prevent APP Cleavage

Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair

Structure of human factor VIIa–soluble tissue factor with calcium, magnesium and rubidium

Sodium‐site in serine protease domain of human coagulation factor IXa: evidence from the crystal structure and molecular dynamics simulations study

Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2

Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis

Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease

An Estimate of the Numbers and Density of Low-Energy Structures

Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimerșs Disease

A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity

PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

P4‐057: PURIFICATION AND CHARACTERIZATION OF SUBPOPULATIONS OF EXTRACELLULAR VESICLES FROM AD AND PD BRAIN AND THEIR SUPPRESSION BY NSMASE2 INHIBITORS

Structural and Functional Studies of γ-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium

Quantifying Vitamin K-dependent Holoprotein Compaction caused by differential γ-carboxylation using HPSEC

Does Protease Domain of Human Factor IXa Contain a Sodium Site? Evidence From the 1.64 Å Resolution Crystal Structure

Platelets Contain Tissue Factor Pathway Inhibitor-2 Derived from Megakaryocytes and Inhibits Fibrinolysis

Engineering Kunitz Domain 1 (KD1) of Human Tissue Factor Pathway Inhibitor-2 to Selectively Inhibit Fibrinolysis: PROPERTIES OF KD1-L17R VARIANT

Quantifying vitamin K-dependent holoprotein compaction caused by differential γ-carboxylation using high-pressure size exclusion chromatography

Structural and Functional Studies of I3-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium

Epitope Mapping of a Monoclonal Antibody to Factor VIII That Inhibits Factor IXa:Factor VIIIa Interaction and Thrombin Activation of Factor VIII

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