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Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics

Molecules (Basel, Switzerland), 2019-01, Vol.24 (2), p.249

Vaara, Martti

2019

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Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics

Frontiers in microbiology, 2019-07, Vol.10, p.1689

Vaara, Martti

2019

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Corrigendum: Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics

Frontiers in microbiology, 2019-10, Vol.10, p.2275-2275

Vaara, Martti

2019

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Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

2017

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Dual-light photodynamic therapy administered daily provides a sustained antibacterial effect on biofilm and prevents Streptococcus mutans adaptation

PloS one, 2020-05, Vol.15 (5), p.e0232775-e0232775

2020

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New polymyxin derivatives that display improved efficacy in animal infection models as compared to polymyxin B and colistin

Medicinal research reviews, 2018-09, Vol.38 (5), p.1661-1673

Vaara, Martti

2018

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A Novel Polymyxin Derivative That Lacks the Fatty Acid Tail and Carries Only Three Positive Charges Has Strong Synergism with Agents Excluded by the Intact Outer Membrane

Antimicrobial Agents and Chemotherapy, 2010-08, Vol.54 (8), p.3341-3346

2010

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Novel Polymyxin Derivatives Carrying Only Three Positive Charges Are Effective Antibacterial Agents

Antimicrobial Agents and Chemotherapy, 2008-09, Vol.52 (9), p.3229-3236

2008

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Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study

The Lancet (British edition), 2010-01, Vol.375 (9710), p.224-230

2010

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Rapid molecular characterization of Acinetobacter baumannii clones with rep-PCR and evaluation of carbapenemase genes by new multiplex PCR in Hospital District of Helsinki and Uusimaa

PloS one, 2014-01, Vol.9 (1), p.e85854-e85854

2014

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Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity

JCI insight, 2018-12, Vol.3 (24)

2018

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Novel derivatives of polymyxins

Journal of antimicrobial chemotherapy, 2013-06, Vol.68 (6), p.1213-1219

Vaara, Martti

2013

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Accurate and Rapid Identification of Candida spp. Frequently Associated with Fungemia by Using PCR and the Microarray-Based Prove-it Sepsis Assay

Journal of Clinical Microbiology, 2012-11, Vol.50 (11), p.3635-3640

2012

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Excretion of the Polymyxin Derivative NAB739 in Murine Urine

Antibiotics (Basel), 2020-03, Vol.9 (4), p.143

2020

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New approaches in peptide antibiotics

Current opinion in pharmacology, 2009-10, Vol.9 (5), p.571-576

Vaara, Martti

2009

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Polymyxins and their novel derivatives

Current opinion in microbiology, 2010-10, Vol.13 (5), p.574-581

Vaara, Martti

2010

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Evaluation of Antimicrobial Therapy of Blood Culture Positive Healthcare-Associated Infections in Children

PloS one, 2015-11, Vol.10 (11), p.e0141555

2015

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Streptococcus mutans Clonal Variation Revealed by Multilocus Sequence Typing

Journal of Clinical Microbiology, 2007-08, Vol.45 (8), p.2616-2625

2007

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The novel polymyxin derivative NAB739 is remarkably less cytotoxic than polymyxin B and colistin to human kidney proximal tubular cells

International journal of antimicrobial agents, 2013-03, Vol.41 (3), p.292-293

2013

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Outer Membrane Permeability Barrier in Escherichia coli Mutants That Are Defective in the Late Acyltransferases of Lipid A Biosynthesis

Antimicrobial Agents and Chemotherapy, 1999-06, Vol.43 (6), p.1459-1462

1999

Volltextzugriff (PDF)

Polymyxin derivatives NAB739 and NAB815 are more effective than polymyxin B in murine Escherichia coli pyelonephritis

Journal of antimicrobial chemotherapy, 2018-02, Vol.73 (2), p.452-455

2018

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Bacteria, phages and septicemia

PloS one, 2007-11, Vol.2 (11), p.e1145-e1145

2007

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Structure–activity studies on novel polymyxin derivatives that carry only three positive charges

Peptides (New York, N.Y. : 1980), 2010-12, Vol.31 (12), p.2318-2321

2010

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Structure–activity studies on polymyxin derivatives carrying three positive charges only reveal a new class of compounds with strong antibacterial activity

Peptides (New York, N.Y. : 1980), 2017-05, Vol.91, p.8-12

2017

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Lipopolysaccharides of polymyxin B‐resistant mutants of Escherichia coii are extensively substituted by 2‐aminoethyl pyrophosphate and contain aminoarabinose in lipid A

Molecular microbiology, 1995-04, Vol.16 (2), p.271-278

1995

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Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics

Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics

Corrigendum: Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics

Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741

Dual-light photodynamic therapy administered daily provides a sustained antibacterial effect on biofilm and prevents Streptococcus mutans adaptation

New polymyxin derivatives that display improved efficacy in animal infection models as compared to polymyxin B and colistin

A Novel Polymyxin Derivative That Lacks the Fatty Acid Tail and Carries Only Three Positive Charges Has Strong Synergism with Agents Excluded by the Intact Outer Membrane

Novel Polymyxin Derivatives Carrying Only Three Positive Charges Are Effective Antibacterial Agents

Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study

Rapid molecular characterization of Acinetobacter baumannii clones with rep-PCR and evaluation of carbapenemase genes by new multiplex PCR in Hospital District of Helsinki and Uusimaa

Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity

Novel derivatives of polymyxins

Accurate and Rapid Identification of Candida spp. Frequently Associated with Fungemia by Using PCR and the Microarray-Based Prove-it Sepsis Assay

Excretion of the Polymyxin Derivative NAB739 in Murine Urine

New approaches in peptide antibiotics

Polymyxins and their novel derivatives

Evaluation of Antimicrobial Therapy of Blood Culture Positive Healthcare-Associated Infections in Children

Streptococcus mutans Clonal Variation Revealed by Multilocus Sequence Typing

The novel polymyxin derivative NAB739 is remarkably less cytotoxic than polymyxin B and colistin to human kidney proximal tubular cells

Outer Membrane Permeability Barrier in Escherichia coli Mutants That Are Defective in the Late Acyltransferases of Lipid A Biosynthesis

Polymyxin derivatives NAB739 and NAB815 are more effective than polymyxin B in murine Escherichia coli pyelonephritis

Bacteria, phages and septicemia

Structure–activity studies on novel polymyxin derivatives that carry only three positive charges

Structure–activity studies on polymyxin derivatives carrying three positive charges only reveal a new class of compounds with strong antibacterial activity

Lipopolysaccharides of polymyxin B‐resistant mutants of Escherichia coii are extensively substituted by 2‐aminoethyl pyrophosphate and contain aminoarabinose in lipid A

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