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Orexins/Hypocretins and Cancer: A Neuropeptide as Emerging Target

Molecules (Basel, Switzerland), 2021-08, Vol.26 (16), p.4849

2021

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The Orexin receptors: Structural and anti-tumoral properties

Frontiers in endocrinology (Lausanne), 2022-07, Vol.13, p.931970-931970

2022

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Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases

Frontiers in endocrinology (Lausanne), 2019-10, Vol.10, p.709-709

2019

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Behavioral and psychological subsyndromes in Alzheimer's disease using the Neuropsychiatric Inventory

International journal of geriatric psychiatry, 2013-08, Vol.28 (8), p.795-803

2013

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Impact of Orexin-A Treatment on Food Intake, Energy Metabolism and Body Weight in Mice

PloS one, 2017-01, Vol.12 (1), p.e0169908-14

2017

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The Orexin-A/OX1R System Induces Cell Death in Pancreatic Cancer Cells Resistant to Gemcitabine and Nab-Paclitaxel Treatment

Frontiers in oncology, 2022-06, Vol.12, p.904327-904327

2022

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The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role

Frontiers in endocrinology (Lausanne), 2018-09, Vol.9, p.573-573

2018

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Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

Cancer research (Chicago, Ill.), 2011-05, Vol.71 (9), p.3341-3351

2011

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The impact of a multi-domain intervention on cerebral glucose metabolism: analysis from the randomized ancillary FDG PET MAPT trial

Alzheimer's research & therapy, 2020-10, Vol.12 (1), p.1-134, Article 134

2020

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Impact of a Pharmacist-included Mobile Geriatrics team intervention on potentially inappropriate drug prescribing: protocol for a prospective feasibility study (PharMoG study)

BMJ open, 2020-12, Vol.10 (12), p.e040917-e040917

2020

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Management of behavioural symptoms of dementia in a specialized unit care

Psychogeriatrics, 2017-03, Vol.17 (2), p.81-88

2017

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Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis

The FASEB journal, 2009-12, Vol.23 (12), p.4069-4080

2009

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PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

The Journal of clinical investigation, 2001-11, Vol.108 (10), p.1483-1494

2001

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Orexins Acting at Native OX1 Receptor in Colon Cancer and Neuroblastoma Cells or at Recombinant OX1 Receptor Suppress Cell Growth by Inducing Apoptosis

The Journal of biological chemistry, 2004-10, Vol.279 (44), p.45875-45886

2004

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Orexin-Induced Apoptosis: The Key Role of the Seven-Transmembrane Domain Orexin Type 2 Receptor

Endocrinology (Philadelphia), 2006-10, Vol.147 (10), p.4977-4984

2006

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Orexins Control Intestinal Glucose Transport by Distinct Neuronal, Endocrine, and Direct Epithelial Pathways

Diabetes (New York, N.Y.), 2007-10, Vol.56 (10), p.2494-2500

2007

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Orexins: A promising target to digestive cancers, inflammation, obesity and metabolism dysfunctions

World journal of gastroenterology : WJG, 2021-11, Vol.27 (44), p.7582-7596

2021

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The orexin receptor OX1R in colon cancer: a promising therapeutic target and a new paradigm in G protein‐coupled receptor signalling through ITIMs

British journal of pharmacology, 2012-03, Vol.165 (6), p.1678-1687

2012

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Nursing Home Admission in Elderly Subjects With Dementia: Predictive Factors and Future Challenges

Journal of the American Medical Directors Association, 2012, Vol.13 (1), p.83.e17-83.e20

2012

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Diagnosis and Treatment of Patients with Severe Alzheimer’s Disease

Drugs & aging, 2009-01, Vol.26 (2), p.135-144

2009

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Spared and impaired abilities in community-dwelling patients entering the severe stage of Alzheimer's disease

Dementia and geriatric cognitive disorders, 2009-01, Vol.28 (5), p.427-417

2009

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A SPECT study of wandering behavior in Alzheimer's disease

International journal of geriatric psychiatry, 2005-09, Vol.20 (9), p.816-820

2005

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Predictors of rapid cognitive decline among demented subjects aged 75 or more: ('Sujet Agé Fragile-Evaluation et Suivi' Cohort-SAFES)

International journal of geriatric psychiatry, 2009-07, Vol.24 (7), p.709-715

2009

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Use of a robotic walking aid in rehabilitation to reduce fear of falling is feasible and acceptable from the end user’s perspective: A randomised comparative study

Maturitas, 2019-02, Vol.120 (5), p.40-46

2019

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Crucial role of the orexin‐B C‐terminus in the induction of OX1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

British journal of pharmacology, 2015-11, Vol.172 (21), p.5211-5223

2015

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Orexins/Hypocretins and Cancer: A Neuropeptide as Emerging Target

The Orexin receptors: Structural and anti-tumoral properties

Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases

Behavioral and psychological subsyndromes in Alzheimer's disease using the Neuropsychiatric Inventory

Impact of Orexin-A Treatment on Food Intake, Energy Metabolism and Body Weight in Mice

The Orexin-A/OX1R System Induces Cell Death in Pancreatic Cancer Cells Resistant to Gemcitabine and Nab-Paclitaxel Treatment

The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role

Aberrant Expression of OX1 Receptors for Orexins in Colon Cancers and Liver Metastases: an Openable Gate to Apoptosis

The impact of a multi-domain intervention on cerebral glucose metabolism: analysis from the randomized ancillary FDG PET MAPT trial

Impact of a Pharmacist-included Mobile Geriatrics team intervention on potentially inappropriate drug prescribing: protocol for a prospective feasibility study (PharMoG study)

Management of behavioural symptoms of dementia in a specialized unit care

Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis

PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

Orexins Acting at Native OX1 Receptor in Colon Cancer and Neuroblastoma Cells or at Recombinant OX1 Receptor Suppress Cell Growth by Inducing Apoptosis

Orexin-Induced Apoptosis: The Key Role of the Seven-Transmembrane Domain Orexin Type 2 Receptor

Orexins Control Intestinal Glucose Transport by Distinct Neuronal, Endocrine, and Direct Epithelial Pathways

Orexins: A promising target to digestive cancers, inflammation, obesity and metabolism dysfunctions

The orexin receptor OX1R in colon cancer: a promising therapeutic target and a new paradigm in G protein‐coupled receptor signalling through ITIMs

Nursing Home Admission in Elderly Subjects With Dementia: Predictive Factors and Future Challenges

Diagnosis and Treatment of Patients with Severe Alzheimer’s Disease

Spared and impaired abilities in community-dwelling patients entering the severe stage of Alzheimer's disease

A SPECT study of wandering behavior in Alzheimer's disease

Predictors of rapid cognitive decline among demented subjects aged 75 or more: ('Sujet Agé Fragile-Evaluation et Suivi' Cohort-SAFES)

Use of a robotic walking aid in rehabilitation to reduce fear of falling is feasible and acceptable from the end user’s perspective: A randomised comparative study

Crucial role of the orexin‐B C‐terminus in the induction of OX1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

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