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Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation

Cell death and differentiation, 2020-07, Vol.27 (7), p.2037-2047

2020

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P53 clears aneuploid cells by entosis

Cell death and differentiation, 2021-02, Vol.28 (2), p.818-820

2021

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Signalling strength determines proapoptotic functions of STING

Nature communications, 2017-09, Vol.8 (1), p.427-10, Article 427

2017

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At a Crossroads to Cancer: How p53-Induced Cell Fate Decisions Secure Genome Integrity

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10883

2021

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Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis

Genes & development, 2016-10, Vol.30 (19), p.2133-2151

2016

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The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance

Journal of cell science, 2017-11, Vol.130 (22), p.3779-3787

2017

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Bcl2 family proteins in carcinogenesis and the treatment of cancer

Apoptosis (London), 2009-04, Vol.14 (4), p.584-596

2009

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Perturbing mitosis for anti‐cancer therapy: is cell death the only answer?

EMBO reports, 2018-03, Vol.19 (3), p.n/a

2018

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MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment

Cell death and differentiation, 2020-08, Vol.27 (8), p.2297-2312

2020

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The PIDDosome activates p53 in response to supernumerary centrosomes

Genes & development, 2017-01, Vol.31 (1), p.34-45

2017

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Expression of the vault RNA protects cells from undergoing apoptosis

Nature communications, 2015-05, Vol.6 (1), p.7030-7030, Article 7030

2015

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The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents

Cell death & disease, 2021-12, Vol.12 (12), p.1151-1151, Article 1151

2021

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Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim

Cell death and differentiation, 2020-02, Vol.27 (2), p.434-450

2020

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miR-326 targets antiapoptotic Bcl-xL and mediates apoptosis in human platelets

PloS one, 2015-04, Vol.10 (4), p.e0122784-e0122784

2015

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Drp1 modulates mitochondrial stress responses to mitotic arrest

Cell death and differentiation, 2020-09, Vol.27 (9), p.2620-2634

2020

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FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

The Journal of experimental medicine, 2006-07, Vol.203 (7), p.1657-1663

2006

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CHK1 dosage in germinal center B cells controls humoral immunity

Cell death and differentiation, 2019-12, Vol.26 (12), p.2551-2567

2019

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The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization

PloS one, 2016-03, Vol.11 (3), p.e0150696-e0150696

2016

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Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system

PloS one, 2013-09, Vol.8 (9), p.e73801-e73801

2013

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p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

Science (American Association for the Advancement of Science), 2003-11, Vol.302 (5647), p.1036-1038

2003

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The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

Frontiers in immunology, 2022-08, Vol.13, p.967914-967914

2022

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The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection

The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2051-2065

2017

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Bacterial fucose-rich polysaccharide stabilizes MAPK-mediated Nrf2/Keap1 signaling by directly scavenging reactive oxygen species during hydrogen peroxide-induced apoptosis of human lung fibroblast cells

PloS one, 2014-11, Vol.9 (11), p.e113663

2014

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Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation

PloS one, 2014-06, Vol.9 (6), p.e99187-e99187

2014

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Apoptosis as a Barrier against CIN and Aneuploidy

Cancers, 2022-12, Vol.15 (1), p.30

2022

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Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation

P53 clears aneuploid cells by entosis

Signalling strength determines proapoptotic functions of STING

At a Crossroads to Cancer: How p53-Induced Cell Fate Decisions Secure Genome Integrity

Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis

The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance

Bcl2 family proteins in carcinogenesis and the treatment of cancer

Perturbing mitosis for anti‐cancer therapy: is cell death the only answer?

MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment

The PIDDosome activates p53 in response to supernumerary centrosomes

Expression of the vault RNA protects cells from undergoing apoptosis

The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim

miR-326 targets antiapoptotic Bcl-xL and mediates apoptosis in human platelets

Drp1 modulates mitochondrial stress responses to mitotic arrest

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

CHK1 dosage in germinal center B cells controls humoral immunity

The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization

Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system

p53- and Drug-Induced Apoptotic Responses Mediated by BH3-Only Proteins Puma and Noxa

The miR-15a/16-1 and miR-15b/16-2 clusters regulate early B cell development by limiting IL-7 receptor expression

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection

Bacterial fucose-rich polysaccharide stabilizes MAPK-mediated Nrf2/Keap1 signaling by directly scavenging reactive oxygen species during hydrogen peroxide-induced apoptosis of human lung fibroblast cells

Leptin is an anti-apoptotic effector in placental cells involving p53 downregulation

Apoptosis as a Barrier against CIN and Aneuploidy

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