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Oral biopharmaceutics tools – Time for a new initiative – An introduction to the IMI project OrBiTo

European journal of pharmaceutical sciences, 2014-06, Vol.57 (SI), p.292-299

2014

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Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1

Drug metabolism and disposition, 2013-03, Vol.41 (3), p.592

2013

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Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds

Toxicology letters, 2007-05, Vol.170 (3), p.214-222

2007

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The effect of folate-binding proteins on bioavailability of folate from milk products

Trends in food science & technology, 2005-06, Vol.16 (6), p.307-310

2005

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Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells

European journal of nutrition, 2005-06, Vol.44 (4), p.242-249

2005

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Physiologically Based Pharmacokinetic Modeling of Cyclohexane as a Tool for Integrating Animal and Human Test Data

International journal of toxicology, 2009-11, Vol.28 (6), p.498-509

2009

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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data

Neurotoxicology (Park Forest South), 2007-07, Vol.28 (4), p.751-760

2007

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Bioavailability of folic acid from fortified pasteurised and UHT-treated milk in humans

European journal of clinical nutrition, 2005-08, Vol.59 (8), p.906-913

2005

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Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologycally based kinetic modeling

Archives of toxicology, 2015, Vol.89 (7)

2015

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Relative developmental toxicity potencies of retinoids in the embryonic stem cell test compared with their relative potencies in in vivo and two other in vitro assays for developmental toxicity

Toxicology letters, 2011-05, Vol.203 (1), p.1-8

2011

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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents

Neurotoxicology (Park Forest South), 2007-07, Vol.28 (4), p.751-760

2007

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Predicted Serum Folate Concentrations Based on In Vitro Studies and Kinetic Modeling are Consistent with Measured Folate Concentrations in Humans

The Journal of nutrition, 2006-12, Vol.136 (12), p.3074-3078

2006

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Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation

Expert opinion on drug metabolism & toxicology, 2012-01, Vol.8 (1), p.11-27

2012

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Folic Acid and 5-Methyltetrahydrofolate in Fortified Milk Are Bioaccessible as Determined in a Dynamic In Vitro Gastrointestinal Model

The Journal of nutrition, 2003-07, Vol.133 (7), p.2377-2383

2003

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Toward relevant biomarkers in in vitro developmental toxicity and their extrapolation to the in vivo situation : Reviews

Expert opinion on drug metabolism & toxicology, 2012, Vol.8 (1)

2012

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Threshold of toxicological concern (TTC) task force: a strategy to support application of TTC to dermally applied cosmetic ingredients

Toxicology letters, 2013-08, Vol.221, p.S35-S35

2013

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Bioaccessibility of Folic Acid and (6S)-5-Methyltetrahydrofolate Decreases after the Addition of Folate-Binding Protein to Yogurt as Studied in a Dynamic In Vitro Gastrointestinal Model

The Journal of nutrition, 2003-11, Vol.133 (11), p.3678-3683

2003

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Decrease of intercellular pH as possible mechanism of action of embryotoxicity of glycol ether alkoxyacetic acid metabolites

Toxicology and applied pharmacology, 2010, Vol.245 (2)

2010

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The Binding of Folic Acid and 5-Methyltetrahydrofolate to Folate-Binding Proteins during Gastric Passage Differs in a Dynamic In Vitro Gastrointestinal Model

The Journal of nutrition, 2004-01, Vol.134 (1), p.31-37

2004

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The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-respomse curves for in vivo developmental toxicity of glycol ethers in rat and man

Toxicological sciences, 2010, Vol.118 (2)

2010

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Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared to the in vivo potency of their parent compounds

Toxicological sciences, 2009, Vol.110 (1)

2009

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Relative developmental toxicity of glycol ethers in the embryonic stem cell test and comparison to their in vivo potency ranking

Reproductive toxicology (Elmsford, N.Y.), 2009-09, Vol.28 (2), p.133-133

2009

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The effect of folatebinding proteins on bioavailability of folate from milk products

Trends in food science & technology, 2005, Vol.16 (6-7), p.307

2005

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Bioaccessibility of Folic Acid and (6S)-5-Methyltetrahydrofolate Decreases after the Addiction of Folate-Binding Protein to Yogurt as Studied in a Dynamic In Vitro Gastrointestinal Model

The Journal of nutrition, 2003, Vol.133

2003

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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Oral biopharmaceutics tools – Time for a new initiative – An introduction to the IMI project OrBiTo

Drug-drug interactions between rosuvastatin and oral antidiabetic drugs occurring at the level of OATP1B1

Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds

The effect of folate-binding proteins on bioavailability of folate from milk products

Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells

Physiologically Based Pharmacokinetic Modeling of Cyclohexane as a Tool for Integrating Animal and Human Test Data

Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data

Bioavailability of folic acid from fortified pasteurised and UHT-treated milk in humans

Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologycally based kinetic modeling

Relative developmental toxicity potencies of retinoids in the embryonic stem cell test compared with their relative potencies in in vivo and two other in vitro assays for developmental toxicity

Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents

Predicted Serum Folate Concentrations Based on In Vitro Studies and Kinetic Modeling are Consistent with Measured Folate Concentrations in Humans

Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation

Folic Acid and 5-Methyltetrahydrofolate in Fortified Milk Are Bioaccessible as Determined in a Dynamic In Vitro Gastrointestinal Model

Toward relevant biomarkers in in vitro developmental toxicity and their extrapolation to the in vivo situation : Reviews

Threshold of toxicological concern (TTC) task force: a strategy to support application of TTC to dermally applied cosmetic ingredients

Bioaccessibility of Folic Acid and (6S)-5-Methyltetrahydrofolate Decreases after the Addition of Folate-Binding Protein to Yogurt as Studied in a Dynamic In Vitro Gastrointestinal Model

Decrease of intercellular pH as possible mechanism of action of embryotoxicity of glycol ether alkoxyacetic acid metabolites

The Binding of Folic Acid and 5-Methyltetrahydrofolate to Folate-Binding Proteins during Gastric Passage Differs in a Dynamic In Vitro Gastrointestinal Model

The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-respomse curves for in vivo developmental toxicity of glycol ethers in rat and man

Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared to the in vivo potency of their parent compounds

Relative developmental toxicity of glycol ethers in the embryonic stem cell test and comparison to their in vivo potency ranking

The effect of folatebinding proteins on bioavailability of folate from milk products

Bioaccessibility of Folic Acid and (6S)-5-Methyltetrahydrofolate Decreases after the Addiction of Folate-Binding Protein to Yogurt as Studied in a Dynamic In Vitro Gastrointestinal Model

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