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PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates

Clinical cancer research, 2021-04, Vol.27 (7), p.2050-2060

2021

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Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

Nature communications, 2018-04, Vol.9 (1), p.1629-11, Article 1629

2018

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Increased KIT Inhibition Enhances Therapeutic Efficacy in Gastrointestinal Stromal Tumor

Clinical cancer research, 2014-05, Vol.20 (9), p.2350-2362

2014

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Fluorine-labeled Dasatinib Nanoformulations as Targeted Molecular Imaging Probes in a PDGFB-driven Murine Glioblastoma Model

Neoplasia (New York, N.Y.), 2012-12, Vol.14 (12), p.1132-IN8

2012

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Loss of p53 Impedes the Antileukemic Response to BCR-ABL Inhibition

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (19), p.7444-7449

2006

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Activity of Dual SRC-ABL Inhibitors Highlights the Role of BCR/ABL Kinase Dynamics in Drug Resistance

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (24), p.9244-9249

2006

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PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Blood, 2005-05, Vol.105 (10), p.3995-4003

2005

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Synthesis and Biological Evaluation of a Fluorine-18 Derivative of Dasatinib

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5853-5857

2007

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Efficacy of HER2-Targeted Intraperitoneal 225Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis

The Journal of nuclear medicine (1978), 2023-09, Vol.64 (9), p.1439-1445

2023

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Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response

Molecular cancer research, 2023-04, Vol.21 (4), p.307-315

2023

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A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy

Clinical cancer research, 2021-01, Vol.27 (2), p.532-541

2021

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Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (15), p.4236-4243

2002

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Imatinib resistance and microcytic erythrocytosis in a Kitⱽ⁵⁵⁸Δ;ᵀ⁶⁶⁹ᴵ/⁺ gatekeeper-mutant mouse model of gastrointestinal stromal tumor

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (34), p.E2276-E2283

2012

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Efficacy of HER2-Targeted Intraperitoneal 225 Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis

Journal of Nuclear Medicine, 2023-09, Vol.64 (9), p.1439-1445

2023

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Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis

Molecular cancer therapeutics, 2022-01, Vol.21 (1), p.125-137

2022

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Engineered Cells as a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications

Bioconjugate chemistry, 2021-04, Vol.32 (4), p.649-654

2021

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Correction to An N‑Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy

Bioconjugate chemistry, 2021-02, Vol.32 (2), p.394-394

2021

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Evaluation of Castration-Resistant Prostate Cancer with Androgen Receptor-Axis Imaging

Journal of Nuclear Medicine, 2016-10, Vol.57 (Suppl 3), p.73S-78S

2016

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Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles

Journal of Nuclear Medicine, 2016-11, Vol.57 (11), p.1771-1777

2016

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First-in-Humans Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted PET

Journal of Nuclear Medicine, 2020-11, Vol.61 (11), p.1580-1587

2020

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Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications

Theranostics, 2023-01, Vol.13 (15), p.5469-5482

2023

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ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts

Molecular pharmaceutics, 2018-06, Vol.15 (6), p.2133-2141

2018

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Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling

EJNMMI research, 2016-12, Vol.6 (1), p.7-7, Article 7

2016

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Alpha radioimmunotherapy using 225 Ac-proteus-DOTA for solid tumors - safety at curative doses

Theranostics, 2020, Vol.10 (25), p.11359-11375

2020

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A magnetic bead-based protein kinase assay with dual detection techniques

Analytical biochemistry, 2011-01, Vol.408 (1), p.5-11

2011

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PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates

Feed-forward alpha particle radiotherapy ablates androgen receptor-addicted prostate cancer

Increased KIT Inhibition Enhances Therapeutic Efficacy in Gastrointestinal Stromal Tumor

Fluorine-labeled Dasatinib Nanoformulations as Targeted Molecular Imaging Probes in a PDGFB-driven Murine Glioblastoma Model

Loss of p53 Impedes the Antileukemic Response to BCR-ABL Inhibition

Activity of Dual SRC-ABL Inhibitors Highlights the Role of BCR/ABL Kinase Dynamics in Drug Resistance

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Synthesis and Biological Evaluation of a Fluorine-18 Derivative of Dasatinib

Efficacy of HER2-Targeted Intraperitoneal 225Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis

Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response

A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy

Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)

Imatinib resistance and microcytic erythrocytosis in a Kitⱽ⁵⁵⁸Δ;ᵀ⁶⁶⁹ᴵ/⁺ gatekeeper-mutant mouse model of gastrointestinal stromal tumor

Efficacy of HER2-Targeted Intraperitoneal 225 Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis

Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis

Engineered Cells as a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications

Correction to An N‑Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy

Evaluation of Castration-Resistant Prostate Cancer with Androgen Receptor-Axis Imaging

Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles

First-in-Humans Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted PET

Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications

ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts

Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling

Alpha radioimmunotherapy using 225 Ac-proteus-DOTA for solid tumors - safety at curative doses

A magnetic bead-based protein kinase assay with dual detection techniques

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