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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

Cell host & microbe, 2020-04, Vol.27 (4), p.642-658.e12

2020

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Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

Rapid communications in mass spectrometry, 2011-12, Vol.25 (23), p.3587-3596

2011

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Comparison of Drug Distribution Images from Whole-Body Thin Tissue Sections Obtained Using Desorption Electrospray Ionization Tandem Mass Spectrometry and Autoradiography

Analytical chemistry (Washington), 2008-07, Vol.80 (13), p.5168-5177

2008

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Liquid microjunction surface sampling probe electrospray mass spectrometry for detection of drugs and metabolites in thin tissue sections

Journal of mass spectrometry., 2008-04, Vol.43 (4), p.500-508

2008

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From molecules to visuals: Empowering drug discovery and development with mass spectrometry imaging

Journal of mass spectrometry., 2024-05, Vol.59 (5), p.e5029-n/a

2024

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Antiviral Efficacy upon Administration of a HepDirect Prodrug of 2′-C-Methylcytidine to Hepatitis C Virus-Infected Chimpanzees

Antimicrobial Agents and Chemotherapy, 2011-08, Vol.55 (8), p.3854-3860

2011

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Optimization of dropletProbe-Mass Spectrometry for Whole-Body Tissue Distribution Analysis of Drug-Like Molecules

Journal of the American Society for Mass Spectrometry, 2020-12, Vol.31 (12), p.2558-2562

2020

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Spatial profiling of stapled α–helical peptide ATSP-7041 in mouse whole-body thin tissue sections using droplet-based liquid microjunction surface sampling-HPLC-ESI–MS/MS

International journal of mass spectrometry, 2019-03, Vol.437 (C), p.17-22

2019

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Combining MALDI mass spectrometry imaging and droplet-base surface sampling analysis for tissue distribution, metabolite profiling, and relative quantification of cyclic peptide melanotan II

Analytica chimica acta, 2020-08, Vol.1125, p.279-287

2020

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Integrated laser ablation-dropletProbe-mass spectrometry for absolute drug quantitation, metabolite detection, and distribution in tissue

Rapid communications in mass spectrometry, 2021-09, Vol.35 (23)

2021

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Development and Application of DropletProbe Mass Spectrometry for Examining Biodistribution of Therapeutics

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2437, p.171

2022

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Absolute quantitation of propranolol from 200‐μm regions of mouse brain and liver thin tissues using laser ablation‐dropletProbe‐mass spectrometry

Rapid communications in mass spectrometry, 2021-01, Vol.35 (5)

2021

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Mass spectrometry imaging of diclofenac and its metabolites in tissues using nanospray desorption electrospray ionization

Analytica chimica acta, 2022-11, Vol.1233, p.340490-340490, Article 340490

2022

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Autonomic Dysfunction Linked to Inhibition of the Na v 1.7 Sodium Channel

Circulation (New York, N.Y.), 2024-04, Vol.149 (17), p.1394

2024

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Online, Absolute Quantitation of Propranolol from Spatially Distinct 20- and 40-μm Dissections of Brain, Liver, and Kidney Thin Tissue Sections by Laser Microdissection–Liquid Vortex Capture–Mass Spectrometry

Analytical chemistry (Washington), 2016-06, Vol.88 (11), p.6026-6034

2016

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Absolute quantitation of propranolol from 200‐μm regions of mouse brain and liver thin tissues using laser ablation‐dropletProbe‐mass spectrometry

Rapid communications in mass spectrometry, 2021-03, Vol.35 (5), p.e9010-n/a

2021

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Extraction efficiency and implications for absolute quantitation of propranolol in mouse brain, liver and kidney tissue sections using droplet-based liquid microjunction surface sampling high-performance liquid chromatography/electrospray ionization tandem mass spectrometry

Rapid communications in mass spectrometry, 2016-07, Vol.30 (14), p.1705-1712

2016

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Simultaneous multielement imaging of liver tissue using laser ablation inductively coupled plasma mass spectrometry

Talanta (Oxford), 2021-12, Vol.235, p.122725-122725, Article 122725

2021

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Integrated laser ablation‐dropletProbe‐mass spectrometry for absolute drug quantitation, metabolite detection, and distribution in tissue

Rapid communications in mass spectrometry, 2021, Vol.35 (23), p.e9202-n/a

2021

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Online, Absolute Quantitation of Propranolol from Spatially Distinct 20- and 40-[mu]m Dissections of Brain, Liver, and Kidney Thin Tissue Sections by Laser Microdissection-Liquid Vortex Capture-Mass Spectrometry

Analytical chemistry (Washington), 2016-06, Vol.88 (11), p.6026

2016

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Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor

Toxicological sciences, 2022-01, Vol.185 (2), p.170-183

2022

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Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.485-496

2022

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Extraction efficiency and implications for absolute quantitation of propranolol in mouse brain, liver and kidney tissue sections using droplet-based liquid microjunction surface sampling high-performance liquid chromatography/electrospray ionization tande: Extraction efficiency and absolute quantitation of propranolol

Rapid communications in mass spectrometry, 2016-07, Vol.30 (14), p.1705-1712

2016

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Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Na v 1.7 for the Treatment of Pain

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.485-496

2022

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The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria

ACS medicinal chemistry letters, 2022-11, Vol.13 (11), p.1745-1754

2022

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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

Comparison of Drug Distribution Images from Whole-Body Thin Tissue Sections Obtained Using Desorption Electrospray Ionization Tandem Mass Spectrometry and Autoradiography

Liquid microjunction surface sampling probe electrospray mass spectrometry for detection of drugs and metabolites in thin tissue sections

From molecules to visuals: Empowering drug discovery and development with mass spectrometry imaging

Antiviral Efficacy upon Administration of a HepDirect Prodrug of 2′-C-Methylcytidine to Hepatitis C Virus-Infected Chimpanzees

Optimization of dropletProbe-Mass Spectrometry for Whole-Body Tissue Distribution Analysis of Drug-Like Molecules

Spatial profiling of stapled α–helical peptide ATSP-7041 in mouse whole-body thin tissue sections using droplet-based liquid microjunction surface sampling-HPLC-ESI–MS/MS

Combining MALDI mass spectrometry imaging and droplet-base surface sampling analysis for tissue distribution, metabolite profiling, and relative quantification of cyclic peptide melanotan II

Integrated laser ablation-dropletProbe-mass spectrometry for absolute drug quantitation, metabolite detection, and distribution in tissue

Development and Application of DropletProbe Mass Spectrometry for Examining Biodistribution of Therapeutics

Absolute quantitation of propranolol from 200‐μm regions of mouse brain and liver thin tissues using laser ablation‐dropletProbe‐mass spectrometry

Mass spectrometry imaging of diclofenac and its metabolites in tissues using nanospray desorption electrospray ionization

Autonomic Dysfunction Linked to Inhibition of the Na v 1.7 Sodium Channel

Online, Absolute Quantitation of Propranolol from Spatially Distinct 20- and 40-μm Dissections of Brain, Liver, and Kidney Thin Tissue Sections by Laser Microdissection–Liquid Vortex Capture–Mass Spectrometry

Absolute quantitation of propranolol from 200‐μm regions of mouse brain and liver thin tissues using laser ablation‐dropletProbe‐mass spectrometry

Extraction efficiency and implications for absolute quantitation of propranolol in mouse brain, liver and kidney tissue sections using droplet-based liquid microjunction surface sampling high-performance liquid chromatography/electrospray ionization tandem mass spectrometry

Simultaneous multielement imaging of liver tissue using laser ablation inductively coupled plasma mass spectrometry

Integrated laser ablation‐dropletProbe‐mass spectrometry for absolute drug quantitation, metabolite detection, and distribution in tissue

Online, Absolute Quantitation of Propranolol from Spatially Distinct 20- and 40-[mu]m Dissections of Brain, Liver, and Kidney Thin Tissue Sections by Laser Microdissection-Liquid Vortex Capture-Mass Spectrometry

Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor

Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain

Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Na v 1.7 for the Treatment of Pain

The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria

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