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The Pathophysiology of Tumor Necrosis Factors

Annual review of immunology, 1992-01, Vol.10 (1), p.411-452

Vassalli, P

1992

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Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death

The Journal of experimental medicine, 1996-11, Vol.184 (5), p.2067-2072

1996

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Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency

The Journal of clinical investigation, 1997-04, Vol.99 (7), p.1699-1703

1997

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Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B

Molecular and Cellular Biology, 1990-04, Vol.10 (4), p.1498-1506

1990

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Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation

Genes & development, 1997-04, Vol.11 (8), p.996-1007

1997

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Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase

Proceedings of the National Academy of Sciences - PNAS, 1995-01, Vol.92 (1), p.160-164

1995

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Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis

The Journal of clinical investigation, 1995-07, Vol.96 (1), p.250-259

1995

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Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

The Journal of experimental medicine, 1990-01, Vol.171 (1), p.35-47

1990

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Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice

The Journal of experimental medicine, 1994-08, Vol.180 (2), p.681-686

1994

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Redirection of tumor metastasis by expression of E-selectin in vivo

The Journal of experimental medicine, 1996-02, Vol.183 (2), p.581-587

1996

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Expression of a tumor necrosis factor α transgene in murine pancreatic β cells results in severe and permanent insulitis without evolution towards diabetes

The Journal of experimental medicine, 1992-12, Vol.176 (6), p.1719-1731

1992

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The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

Cell, 1989-03, Vol.56 (5), p.731-740

1989

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Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis

The Journal of experimental medicine, 1989-09, Vol.170 (3), p.655-663

1989

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γ interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors

The Journal of experimental medicine, 1986-12, Vol.164 (6), p.2113-2118

1986

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Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation

The Journal of experimental medicine, 1991-02, Vol.173 (2), p.471-481

1991

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Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease

The Journal of experimental medicine, 1987-11, Vol.166 (5), p.1280-1289

1987

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Monoclonal Antibody against Interferon γ Can Prevent Experimental Cerebral Malaria and its Associated Overproduction of Tumor Necrosis Factor

Proceedings of the National Academy of Sciences - PNAS, 1989-07, Vol.86 (14), p.5572-5574

1989

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Tumor necrosis factor is a critical mediator in hapten-induced irritant and contact hypersensitivity reactions

The Journal of experimental medicine, 1991-03, Vol.173 (3), p.673-679

1991

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Cloning and expression of a mouse macrophage cDNA coding for a membrane glycoprotein of the scavenger receptor cysteine-rich domain family

The Journal of biological chemistry, 1994-02, Vol.269 (8), p.5512-5517

1994

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Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation

The Journal of experimental medicine, 1994-08, Vol.180 (2), p.673-679

1994

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An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis

The EMBO journal, 1997-05, Vol.16 (9), p.2262-2270

1997

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Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice

Infection and Immunity, 1997-02, Vol.65 (2), p.457-465

1997

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Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice

The Journal of experimental medicine, 2003-02, Vol.197 (3), p.333-341

2003

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Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis

The American journal of pathology, 1990-01, Vol.136 (1), p.103-110

1990

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In vitro Rapid Organization of Endothelial Cells into Capillary-Like Networks Is Promoted by Collagen Matrices

The Journal of cell biology, 1983-11, Vol.97 (5), p.1648-1652

1983

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The Pathophysiology of Tumor Necrosis Factors

Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death

Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency

Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B

Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation

Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase

Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice

Redirection of tumor metastasis by expression of E-selectin in vivo

Expression of a tumor necrosis factor α transgene in murine pancreatic β cells results in severe and permanent insulitis without evolution towards diabetes

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis

γ interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation

Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease

Monoclonal Antibody against Interferon γ Can Prevent Experimental Cerebral Malaria and its Associated Overproduction of Tumor Necrosis Factor

Tumor necrosis factor is a critical mediator in hapten-induced irritant and contact hypersensitivity reactions

Cloning and expression of a mouse macrophage cDNA coding for a membrane glycoprotein of the scavenger receptor cysteine-rich domain family

Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation

An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis

Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice

Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice

Subcutaneous perfusion of tumor necrosis factor induces local proliferation of fibroblasts, capillaries, and epidermal cells, or massive tissue necrosis

In vitro Rapid Organization of Endothelial Cells into Capillary-Like Networks Is Promoted by Collagen Matrices

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