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Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans

Journal of the American College of Cardiology, 2013-02, Vol.61 (7), p.723-727

2013

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Characterization of the Adenosine Pharmacology of Ticagrelor Reveals Therapeutically Relevant Inhibition of Equilibrative Nucleoside Transporter 1

Journal of cardiovascular pharmacology and therapeutics, 2014-03, Vol.19 (2), p.209-219

2014

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Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI

Stroke (1970), 2019-11, Vol.50 (11), p.3004-3012

2019

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Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

Journal of cardiovascular pharmacology and therapeutics, 2012-06, Vol.17 (2), p.164-172

2012

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Ticagrelor: The First Reversibly Binding Oral P2Y12 Receptor Antagonist

Cardiovascular therapeutics, 2009, Vol.27 (4), p.259-274

2009

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Adjunctive treatment with ticagrelor, but not clopidogrel, added to tPA enables sustained coronary artery recanalisation with recovery of myocardium perfusion in a canine coronary thrombosis model

Thrombosis and haemostasis, 2010-09, Vol.104 (3), p.609-917

2010

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Lead Optimization of Ethyl 6‑Aminonicotinate Acyl Sulfonamides as Antagonists of the P2Y12 Receptor. Separation of the Antithrombotic Effect and Bleeding for Candidate Drug AZD1283

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.7015-7024

2013

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Stabilizing Role of Platelet P2Y12 Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques

PloS one, 2010-04, Vol.5 (4), p.e10130

2010

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Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication

Haematologica (Roma), 2015-09, Vol.100 (9), p.1131-1138

2015

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Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP‐induced receptor signaling and platelet aggregation

Journal of thrombosis and haemostasis, 2009-09, Vol.7 (9), p.1556-1565

2009

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Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation

Journal of thrombosis and haemostasis, 2009-09, Vol.7 (9), p.1556-1565

2009

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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (10), p.2877-2881

2011

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Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

Thrombosis research, 2009-11, Vol.124 (5), p.565-571

2009

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Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor

Thrombosis and haemostasis, 2011-12, Vol.106 (6), p.1179

2011

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Comparison of ticagrelor and thienopyridine P2Y(12) binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

Thrombosis research, 2009-11, Vol.124 (5), p.565-571

2009

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Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y12 antagonists in an ex-vivo canine model

Thrombosis research, 2012-10, Vol.130 (4), p.622-628

2012

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The effect of water on the activity of supported palladium catalysts in the catalytic combustion of methane

Catalysis today, 1999, Vol.47 (1), p.287-293

1999

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Synthesis, structure–property relationships and pharmacokinetic evaluation of ethyl 6-aminonicotinate sulfonylureas as antagonists of the P2Y12 receptor

European journal of medicinal chemistry, 2013-07, Vol.65, p.360-375

2013

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LETTER: Dyspnoea and antiplatelet agents: revisited

International journal of clinical practice (Esher), 2007-09, Vol.61 (9), p.1590

2007

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Optimizing platelet inhibition

European Heart Journal Supplements, 2008-05, Vol.10 (suppl-D), p.D23-D29

VAN GIEZEN, J. J. J

2008

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Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y(12) antagonists in an ex-vivo canine model

Thrombosis research, 2012-10, Vol.130 (4), p.622-628

2012

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Dyspnoea and antiplatelet agents: revisited

International journal of clinical practice (Esher), 2007-09, Vol.61 (9), p.1590-1590

2007

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Optimization of ketone-based P2Y(12) receptor antagonists as antithrombotic agents: pharmacodynamics and receptor kinetics considerations

Bioorganic & medicinal chemistry letters, 2014-07, Vol.24 (13), p.2963-2968

2014

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Evaluation of platelet function, a method comparison

Platelets (Edinburgh), 2006-02, Vol.17 (1), p.49-55

2006

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Incompatibility of Lactobacillus Vectors with Replicons Derived from Small Cryptic Lactobacillus Plasmids and Segregational Instability of the Introduced Vectors

Applied and Environmental Microbiology, 1991-06, Vol.57 (6), p.1822-1828

1991

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Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans

Characterization of the Adenosine Pharmacology of Ticagrelor Reveals Therapeutically Relevant Inhibition of Equilibrative Nucleoside Transporter 1

Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI

Ticagrelor Inhibits Adenosine Uptake In Vitro and Enhances Adenosine-Mediated Hyperemia Responses in a Canine Model

Ticagrelor: The First Reversibly Binding Oral P2Y12 Receptor Antagonist

Adjunctive treatment with ticagrelor, but not clopidogrel, added to tPA enables sustained coronary artery recanalisation with recovery of myocardium perfusion in a canine coronary thrombosis model

Lead Optimization of Ethyl 6‑Aminonicotinate Acyl Sulfonamides as Antagonists of the P2Y12 Receptor. Separation of the Antithrombotic Effect and Bleeding for Candidate Drug AZD1283

Stabilizing Role of Platelet P2Y12 Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques

Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication

Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP‐induced receptor signaling and platelet aggregation

Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation

A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor

Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor

Comparison of ticagrelor and thienopyridine P2Y(12) binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y12 antagonists in an ex-vivo canine model

The effect of water on the activity of supported palladium catalysts in the catalytic combustion of methane

Synthesis, structure–property relationships and pharmacokinetic evaluation of ethyl 6-aminonicotinate sulfonylureas as antagonists of the P2Y12 receptor

LETTER: Dyspnoea and antiplatelet agents: revisited

Optimizing platelet inhibition

Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y(12) antagonists in an ex-vivo canine model

Dyspnoea and antiplatelet agents: revisited

Optimization of ketone-based P2Y(12) receptor antagonists as antithrombotic agents: pharmacodynamics and receptor kinetics considerations

Evaluation of platelet function, a method comparison

Incompatibility of Lactobacillus Vectors with Replicons Derived from Small Cryptic Lactobacillus Plasmids and Segregational Instability of the Introduced Vectors

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