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The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: Oxidative stress and the seesaw of cell survival and death

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2012-09, Vol.163 (1), p.26-36

2012

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Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness

Experimental cell research, 2007-05, Vol.313 (8), p.1615-1627

2007

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Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61

Molecular cancer research, 2009-01, Vol.7 (1), p.23-32

2009

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The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

Cancer chemotherapy and pharmacology, 2014-05, Vol.73 (5), p.983-990

2014

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Sphingolipid signaling pathways as potential therapeutic targets in gliomas

Mini reviews in medicinal chemistry, 2007-10, Vol.7 (10), p.984-990

Van Brocklyn, James R

2007

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Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line

BMC bioinformatics, 2006-08, Vol.7 (1), p.373-373, Article 373

2006

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Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

Science (American Association for the Advancement of Science), 1998-03, Vol.279 (5356), p.1552-1555

1998

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Human Cytomegalovirus Regulates Bioactive Sphingolipids

The Journal of biological chemistry, 2008-09, Vol.283 (38), p.26148-26160

2008

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Signal transduction of sphingosine-1-phosphate G protein-coupled receptors

TheScientificWorld, 2006-08, Vol.6, p.946-966

2006

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Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells

Cancer letters, 2003-09, Vol.199 (1), p.53-60

2003

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Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase β

Cancer letters, 2002-07, Vol.181 (2), p.195-204

2002

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Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors

The Journal of biological chemistry, 2008-05, Vol.283 (18), p.12175-12187

2008

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Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19), p.5364-5370

2014

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Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma

Neuro-oncology (Charlottesville, Va.), 2012-04, Vol.14 (4), p.405-415

2012

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Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1

Molecular biology of the cell, 1999-04, Vol.10 (4), p.1179-1190

1999

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Cellular metabolic rate is influenced by life-history traits in tropical and temperate birds

PloS one, 2014-01, Vol.9 (1), p.e87349-e87349

2014

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The role of sphingosine kinase-1 in EGFRvIII-regulated growth and survival of glioblastoma cells

Journal of neuro-oncology, 2011-05, Vol.102 (3), p.353-366

2011

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N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide

Biochemistry (Easton), 1998-09, Vol.37 (37), p.12892-12898

1998

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Sphingosine 1-phosphate pKa and binding constants: intramolecular and intermolecular influences

Journal of molecular graphics & modelling, 2007-09, Vol.26 (2), p.519-528

2007

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Identification of the Hydrophobic Ligand Binding Pocket of the S1P1 Receptor

The Journal of biological chemistry, 2007-01, Vol.282 (4), p.2374-2385

2007

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Regulation of cancer cell migration and invasion by sphingosine-1-phosphate

World journal of biological chemistry, 2010-10, Vol.1 (10), p.307-312

Brocklyn, James R Van

2010

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Immunosuppressive human anti-lymphocyte autoantibodies specific for the type 1 sphingosine 1-phosphate receptor

The FASEB journal, 2009-06, Vol.23 (6), p.1786-1796

2009

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Homodimerization and heterodimerization of S1P/EDG sphingosine-1-phosphate receptors

BBA - Molecular and Cell Biology of Lipids, 2002-05, Vol.1582 (1), p.89-93

2002

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Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6

Blood, 2000-04, Vol.95 (8), p.2624-2629

2000

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The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: Oxidative stress and the seesaw of cell survival and death

Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness

Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61

The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

Sphingolipid signaling pathways as potential therapeutic targets in gliomas

Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line

Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

Human Cytomegalovirus Regulates Bioactive Sphingolipids

Signal transduction of sphingosine-1-phosphate G protein-coupled receptors

Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells

Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase β

Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors

Aurora-A inhibition offers a novel therapy effective against intracranial glioblastoma

Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma

Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1

Cellular metabolic rate is influenced by life-history traits in tropical and temperate birds

The role of sphingosine kinase-1 in EGFRvIII-regulated growth and survival of glioblastoma cells

N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide

Sphingosine 1-phosphate pKa and binding constants: intramolecular and intermolecular influences

Identification of the Hydrophobic Ligand Binding Pocket of the S1P1 Receptor

Regulation of cancer cell migration and invasion by sphingosine-1-phosphate

Immunosuppressive human anti-lymphocyte autoantibodies specific for the type 1 sphingosine 1-phosphate receptor

Homodimerization and heterodimerization of S1P/EDG sphingosine-1-phosphate receptors

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6

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