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Chiral selection in poly(C)-directed synthesis of oligo(G)

Nature (London), 1984-08, Vol.310 (5978), p.602-604

1984

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Synthesis of α-Glucosidase I Inhibitors Showing Antiviral (HIV-1) and Immunosuppressive Activity

Journal of pharmacy and pharmacology, 1996-02, Vol.48 (2), p.172-178

1996

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The First Orally Active Low Molecular Weight Agonists for the LH Receptor: Thienopyr(im)idines with Therapeutic Potential for Ovulation Induction

Chembiochem : a European journal of chemical biology, 2002-10, Vol.3 (10), p.1023-1026

2002

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Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys

Infection and Immunity, 1992-05, Vol.60 (5), p.1826-1833

1992

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1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (5), p.685-690

1999

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A mechanism for heparin-induced potentiation of antithrombin III

Nature structural & molecular biology, 1994-07, Vol.1 (7), p.423-425

1994

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Medicinal chemistry education: what is needed and where is it going?

Drug development research, 2005-09, Vol.66 (1), p.1-8

2005

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Heparin: from the original "soup" to well-designed heparin mimetics

Pure and applied chemistry, 1997-01, Vol.69 (9), p.1839-1846

1997

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A review of the methods of chemical synthesis of sulphate and glucuronide conjugates

Xenobiotica, 1987, Vol.17 (12), p.1451-1471

1987

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Design, synthesis and testing of amino-bicycloaryl based orally bioavailable thrombin inhibitors

Bioorganic & medicinal chemistry letters, 1999-10, Vol.9 (19), p.2837-2842

1999

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Amplification of chirality based upon the association of nucleic acid strands of opposite handedness

Journal of molecular evolution, 1987-06, Vol.25 (2), p.100-105

1987

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The Unique Antithrombin III Binding Domain of Heparin: A Lead to New Synthetic Antithrombotics

Angewandte Chemie (International ed.), 1993-12, Vol.32 (12), p.1671-1690

1993

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Biological properties of synthetic glycoconjugate mimics of heparin comprising different molecular spacers

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2081-2086

1998

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Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains

Bioorganic & medicinal chemistry, 1999-09, Vol.7 (9), p.1881-1890

1999

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Specific recognition of antibody-oligonucleotide conjugates by radiolabeled antisense nucleotides: a novel approach for two-step radioimmunotherapy of cancer

Bioconjugate chemistry, 1993-01, Vol.4 (1), p.94-102

1993

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In vitro evaluation of DNA-DNA hybridization as a two-step approach in radioimmunotherapy of cancer

Cancer research (Chicago, Ill.), 1994-07, Vol.54 (13), p.3479-3486

1994

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In vitro evaluation of synthetic heparin-like conjugates comprising different thrombin binding domains

Bioorganic & medicinal chemistry letters, 1998-05, Vol.8 (10), p.1201-1206

1998

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Targeting RNA: new opportunities to address drugless targets

Drug Discovery Today, 2003-04, Vol.8 (7), p.297-306

2003

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Fluorescence assays for high-throughput screening of protein kinases

Combinatorial chemistry & high throughput screening, 2003-06, Vol.6 (4), p.313-320

2003

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Stereoselective Transformations on d-Glucose-Derived Eight-Membered Ring Carbocycles

Organic letters, 2001-03, Vol.3 (5), p.731-733

2001

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Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (14), p.2013-2018

1999

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Synthetic heparin-like antithrombotics

Pure and applied chemistry, 1997-01, Vol.69 (3), p.389-394

van Boeckel, C. A. A.

1997

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Pharmacological profile of the chemically synthesized antithrombin III binding fragment of heparin (pentasaccharide) in rats

Thrombosis and haemostasis, 1990, Vol.63 (2), p.265-270

1990

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The application of the AMB protective group in the solid-phase synthesis of methylphosphonate DNA analogues

Nucleic acids research, 1993-07, Vol.21 (15), p.3493-3500

1993

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Carbohydrates and drug discovery — the role of computer simulation

Trends in biotechnology (Regular ed.), 1994, Vol.12 (1), p.9-14

1994

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Chiral selection in poly(C)-directed synthesis of oligo(G)

Synthesis of α-Glucosidase I Inhibitors Showing Antiviral (HIV-1) and Immunosuppressive Activity

The First Orally Active Low Molecular Weight Agonists for the LH Receptor: Thienopyr(im)idines with Therapeutic Potential for Ovulation Induction

Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys

1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors

A mechanism for heparin-induced potentiation of antithrombin III

Medicinal chemistry education: what is needed and where is it going?

Heparin: from the original "soup" to well-designed heparin mimetics

A review of the methods of chemical synthesis of sulphate and glucuronide conjugates

Design, synthesis and testing of amino-bicycloaryl based orally bioavailable thrombin inhibitors

Amplification of chirality based upon the association of nucleic acid strands of opposite handedness

The Unique Antithrombin III Binding Domain of Heparin: A Lead to New Synthetic Antithrombotics

Biological properties of synthetic glycoconjugate mimics of heparin comprising different molecular spacers

Synthesis of heparin-like antithrombotics having perphosphorylated thrombin binding domains

Specific recognition of antibody-oligonucleotide conjugates by radiolabeled antisense nucleotides: a novel approach for two-step radioimmunotherapy of cancer

In vitro evaluation of DNA-DNA hybridization as a two-step approach in radioimmunotherapy of cancer

In vitro evaluation of synthetic heparin-like conjugates comprising different thrombin binding domains

Targeting RNA: new opportunities to address drugless targets

Fluorescence assays for high-throughput screening of protein kinases

Stereoselective Transformations on d-Glucose-Derived Eight-Membered Ring Carbocycles

Design and synthesis of a novel synthetic NAPAP-penta-saccharide conjugate displaying a dual antithrombotic action

Synthetic heparin-like antithrombotics

Pharmacological profile of the chemically synthesized antithrombin III binding fragment of heparin (pentasaccharide) in rats

The application of the AMB protective group in the solid-phase synthesis of methylphosphonate DNA analogues

Carbohydrates and drug discovery — the role of computer simulation

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