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Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.528-537

1997

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Synthesis of the Four Isomers of 4-Aminopyrrolidine-2,4-dicarboxylate: Identification of a Potent, Highly Selective, and Systemically-Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase

Journal of medicinal chemistry, 1996-07, Vol.39 (15), p.2990-3000

1996

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1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [ 3H]norepinephrine release in rat hippocampal slices

Neuropharmacology, 1995-02, Vol.34 (2), p.141-147

1995

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A Concise, Stereocontrolled Thiazolium Ylide Approach to Kainic Acid

Journal of organic chemistry, 1994-05, Vol.59 (10), p.2773-2778

1994

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Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogs of ranitidine

Journal of medicinal chemistry, 1992-03, Vol.35 (6), p.1102-1108

1992

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Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine

Journal of medicinal chemistry, 1992-08, Vol.35 (17), p.3141-3147

1992

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Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4- dicarboxylate

Neuropharmacology, 1995-08, Vol.34 (8), p.843-850

1995

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Synthesis and Metabotropic Glutamate Receptor Activity of S-Oxidized Variants of (−)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate: Identification of Potent, Selective, and Orally Bioavailable Agonists for mGlu2/3 Receptors

Journal of medicinal chemistry, 2007-01, Vol.50 (2), p.233-240

2007

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Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R, 4R-4-aminopyrrolidine-2,4-dicarboxylic acid

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (15), p.1985-1990

1998

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Methyl Substitution of 2-Aminobicyclo[3.1.0]hexane 2,6-Dicarboxylate (LY354740) Determines Functional Activity at Metabotropic Glutamate Receptors: Identification of a Subtype Selective mGlu2 Receptor Agonist

Journal of medicinal chemistry, 2005-05, Vol.48 (10), p.3605-3612

2005

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The synthesis of isotopically labeled (+)-2-amino bicyclo[3.1.0]hexane-2,6-carboxylic acid and its 2-oxa-and 2-thia-analogs

Journal of labelled compounds & radiopharmaceuticals, 2005-07, Vol.48 (8), p.605-620

2005

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Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate: Metabotropic glutamate receptors

Neuropharmacology, 1995, Vol.34 (8), p.843-850

1995

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INTRACEREBRAL INJECTIONS OF METABOTROPIC GLUTAMATE RECEPTOR AGONISTS CAN INDUCE OR PROTECT AGAINST LIMBIC SEIZURES IN MICE

Behavioural pharmacology, 1995-08, Vol.6 (5), p.633

1995

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Synthesis and pharmacological characterization of l- trans-4-tetrazolylproline (ly300020): A novel systemically-active ampa receptor agonist

Bioorganic & medicinal chemistry letters, 1993, Vol.3 (1), p.95-98

1993

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ChemInform Abstract: A Concise, Stereocontrolled Thiazolium Ylide Approach to Kainic Acid

ChemInform, 1994-12, Vol.25 (49), p.no-no

1994

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Théorie des systèmes dynamiques: Une introduction

2021

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Analyse complexe et équations différentielles: Exercices corrigés

2021

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ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Antagonist Activity of N1-Substituted Analogues of 2R,4R-4-Aminopyrrolidine-2,4-dicarboxylic Acid

ChemInform, 1998-11, Vol.29 (47), p.no-no

1998

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ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Antagonist Activity of N 1 ‐Substituted Analogues of 2R,4R‐4‐Aminopyrrolidine‐2,4‐dicarboxylic Acid

ChemInform, 1998-11, Vol.29 (47)

1998

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INTRACEREBRAL INJECTIONS OF METABOTROPIC GLUTAMATE RECEPTOR AGONISTS CAN INDUCE OR PROTECT AGAINST LIMBIC SEIZURES IN MICE

Behavioural pharmacology, 1995-08, Vol.6 (56), p.633-633

1995

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Internal Mammary and Medial Supraclavicular Irradiation in Breast Cancer

The New England journal of medicine, 2015-07, Vol.373 (4), p.317-327

2015

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HEPfit: a code for the combination of indirect and direct constraints on high energy physics models

The European physical journal. C, Particles and fields, 2020-05, Vol.80 (5), p.1-31, Article 456

2020

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Le Nouveau Festin de Pierre, ou l’Athée Foudroyé: Édition, notes et présentation par Daniela Dalla Valle

2020

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ChemInform Abstract: Synthesis of the Four Isomers of 4-Aminopyrrolidine-2,4-dicarboxylate: Identification of a Potent, Highly Selective, and Systemically-Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase

ChemInform, 1996-10, Vol.27 (44), p.no-no

1996

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Synthesis, Pharmacological Characterization, and Molecular Modeling of Heterobicyclic Amino Acids Related to (+)-2-Aminobicyclo[3.1.0]hexane- 2,6-dicarboxylic Acid (LY354740): Identification of Two New Potent, Selective, and Systemically Active Agonists for Group II Metabotropic Glutamate Receptors

Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

Synthesis of the Four Isomers of 4-Aminopyrrolidine-2,4-dicarboxylate: Identification of a Potent, Highly Selective, and Systemically-Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase

1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [ 3H]norepinephrine release in rat hippocampal slices

A Concise, Stereocontrolled Thiazolium Ylide Approach to Kainic Acid

Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogs of ranitidine

Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine

Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4- dicarboxylate

Synthesis and Metabotropic Glutamate Receptor Activity of S-Oxidized Variants of (−)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate: Identification of Potent, Selective, and Orally Bioavailable Agonists for mGlu2/3 Receptors

Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R, 4R-4-aminopyrrolidine-2,4-dicarboxylic acid

Methyl Substitution of 2-Aminobicyclo[3.1.0]hexane 2,6-Dicarboxylate (LY354740) Determines Functional Activity at Metabotropic Glutamate Receptors: Identification of a Subtype Selective mGlu2 Receptor Agonist

The synthesis of isotopically labeled (+)-2-amino bicyclo[3.1.0]hexane-2,6-carboxylic acid and its 2-oxa-and 2-thia-analogs

Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate: Metabotropic glutamate receptors

INTRACEREBRAL INJECTIONS OF METABOTROPIC GLUTAMATE RECEPTOR AGONISTS CAN INDUCE OR PROTECT AGAINST LIMBIC SEIZURES IN MICE

Synthesis and pharmacological characterization of l- trans-4-tetrazolylproline (ly300020): A novel systemically-active ampa receptor agonist

ChemInform Abstract: A Concise, Stereocontrolled Thiazolium Ylide Approach to Kainic Acid

Théorie des systèmes dynamiques: Une introduction

Analyse complexe et équations différentielles: Exercices corrigés

ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Antagonist Activity of N1-Substituted Analogues of 2R,4R-4-Aminopyrrolidine-2,4-dicarboxylic Acid

ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Antagonist Activity of N 1 ‐Substituted Analogues of 2R,4R‐4‐Aminopyrrolidine‐2,4‐dicarboxylic Acid

INTRACEREBRAL INJECTIONS OF METABOTROPIC GLUTAMATE RECEPTOR AGONISTS CAN INDUCE OR PROTECT AGAINST LIMBIC SEIZURES IN MICE

Internal Mammary and Medial Supraclavicular Irradiation in Breast Cancer

HEPfit: a code for the combination of indirect and direct constraints on high energy physics models

Le Nouveau Festin de Pierre, ou l’Athée Foudroyé: Édition, notes et présentation par Daniela Dalla Valle

ChemInform Abstract: Synthesis of the Four Isomers of 4-Aminopyrrolidine-2,4-dicarboxylate: Identification of a Potent, Highly Selective, and Systemically-Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase

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