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Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

BMC cancer, 2012-01, Vol.12 (1), p.15-15, Article 15

2012

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Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

The Journal of biological chemistry, 2003-03, Vol.278 (10), p.7743-7746

2003

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Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex

Journal of medicinal chemistry, 2008-02, Vol.51 (4), p.737-751

2008

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The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

FEBS letters, 2002-07, Vol.523 (1), p.171-176

2002

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IRC‐083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells

International journal of cancer, 2009-03, Vol.124 (6), p.1449-1456

2009

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JNK is Associated with Bcl-2 and PP1 in Mitochondria: Paclitaxel Induces Its Activation and Its Association with the Phosphorylated Form of Bcl-2

Cell cycle (Georgetown, Tex.), 2004-10, Vol.3 (10), p.1312-1319

2004

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Characterization of the antiproliferative activity of Xylopia aethiopica

Cell division, 2012-03, Vol.7 (1), p.8-8, Article 8

2012

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Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells

Oncogene, 2003-05, Vol.22 (21), p.3260-3268

2003

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Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents

Cell cycle (Georgetown, Tex.), 2008-07, Vol.7 (14), p.2234-2240

2008

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Benzo[e]pyridoindoles, novel inhibitors of the Aurora kinases

Cell cycle (Georgetown, Tex.), 2009-03, Vol.8 (5), p.765-772

2009

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Localization of Phosphorylated Forms of Bcl-2 in Mitosis : Co-Localization with Ki-67 and Nucleolin in Nuclear Structures and on Mitotic Chromosomes

Cell cycle (Georgetown, Tex.), 2005-04, Vol.4 (4), p.583-589

2005

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BRCA1 Downregulation Leads to Premature Inactivation of Spindle Checkpoint and Confers Paclitaxel Resistance

Cell cycle (Georgetown, Tex.), 2006-05, Vol.5 (9), p.1001-1007

2006

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The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells

The Journal of immunology (1950), 2011-10, Vol.187 (7), p.3806-3814

2011

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OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals

Experimental cell research, 2007-10, Vol.313 (17), p.3800-3808

2007

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Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids

European journal of cancer (1990), 2009-09, Vol.45 (13), p.2402-2411

2009

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A 3D in vitro spheroid model as a way to study the mechanisms of electroporation

International journal of pharmaceutics, 2009-09, Vol.379 (2), p.278-284

2009

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Bcl-2 Phosphorylation and Proteasome-Dependent Degradation Induced by Paclitaxel Treatment: Consequences on Sensitivity of Isolated Mitochondria to Bid

Experimental cell research, 2002-08, Vol.278 (1), p.101-111

2002

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Estrogen and antiestrogen-dependent regulation of breast cancer cell proliferation in multicellular spheroids : Influence of cell microenvironment

International journal of oncology, 2008-05, Vol.32 (5), p.1033-1039

2008

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PP1 phosphatase is involved in Bcl-2 dephosphorylation after prolonged mitotic arrest induced by paclitaxel

Biochemical and biophysical research communications, 2002-06, Vol.294 (2), p.504-508

2002

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Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition

FEBS letters, 1999-02, Vol.444 (1), p.32-37

1999

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Localization of phosphorylated forms of Bcl-2 in mitosis: co-localization with Ki-67 and nucleolin in nuclear structures and on mitotic chromosomes

Cell cycle (Georgetown, Tex.), 2005-04, Vol.4 (4), p.590-6

2005

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Up‐regulation of cdc2 protein during paclitaxel‐induced apoptosis

International journal of cancer, 2000-09, Vol.87 (6), p.779-786

2000

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Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases

Cell cycle (Georgetown, Tex.), 2009-03, Vol.8 (5), p.765-72

2009

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Phosphorylation and Proteasome-Dependent Degradation of Bcl-2 in Mitotic-Arrested Cells after Microtubule Damage

Biochemical and biophysical research communications, 1999-09, Vol.262 (3), p.823-827

1999

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Z-Ajoene Induces Apoptosis of HL-60 Cells: Involvement of Bcl-2 Cleavage

Nutrition and cancer, 2002-01, Vol.42 (2), p.241-247

2002

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Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer

Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis

Meriolins (3-(Pyrimidin-4-yl)-7-azaindoles): Synthesis, Kinase Inhibitory Activity, Cellular Effects, and Structure of a CDK2/Cyclin A/Meriolin Complex

The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

IRC‐083864, a novel bis quinone inhibitor of CDC25 phosphatases active against human cancer cells

JNK is Associated with Bcl-2 and PP1 in Mitochondria: Paclitaxel Induces Its Activation and Its Association with the Phosphorylated Form of Bcl-2

Characterization of the antiproliferative activity of Xylopia aethiopica

Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells

Moderate variations in CDC25B protein levels modulate the response to DNA damaging agents

Benzo[e]pyridoindoles, novel inhibitors of the Aurora kinases

Localization of Phosphorylated Forms of Bcl-2 in Mitosis : Co-Localization with Ki-67 and Nucleolin in Nuclear Structures and on Mitotic Chromosomes

BRCA1 Downregulation Leads to Premature Inactivation of Spindle Checkpoint and Confers Paclitaxel Resistance

The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells

OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals

Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids

A 3D in vitro spheroid model as a way to study the mechanisms of electroporation

Bcl-2 Phosphorylation and Proteasome-Dependent Degradation Induced by Paclitaxel Treatment: Consequences on Sensitivity of Isolated Mitochondria to Bid

Estrogen and antiestrogen-dependent regulation of breast cancer cell proliferation in multicellular spheroids : Influence of cell microenvironment

PP1 phosphatase is involved in Bcl-2 dephosphorylation after prolonged mitotic arrest induced by paclitaxel

Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition

Localization of phosphorylated forms of Bcl-2 in mitosis: co-localization with Ki-67 and nucleolin in nuclear structures and on mitotic chromosomes

Up‐regulation of cdc2 protein during paclitaxel‐induced apoptosis

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases

Phosphorylation and Proteasome-Dependent Degradation of Bcl-2 in Mitotic-Arrested Cells after Microtubule Damage

Z-Ajoene Induces Apoptosis of HL-60 Cells: Involvement of Bcl-2 Cleavage

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