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Roles and mechanisms of alternative splicing in cancer - implications for care

Nature reviews. Clinical oncology, 2020-08, Vol.17 (8), p.457-474

2020

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MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia

PloS one, 2006-12, Vol.1 (1), p.e116-e116

2006

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Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types

PloS one, 2009-12, Vol.4 (12), p.e8419-e8419

2009

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The Spliceosome: The Ultimate RNA Chaperone and Sculptor

Trends in biochemical sciences (Amsterdam. Regular ed.), 2016-01, Vol.41 (1), p.33-45

2016

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RNA-binding proteins in human genetic disease

Nature reviews. Genetics, 2021-03, Vol.22 (3), p.185-198

2021

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Bridging the Gap: Assessing Material Performance of Laboratory Specimens and Concrete Structures

Materials, 2023-06, Vol.16 (12), p.4306

2023

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Histone deacetylase activity modulates alternative splicing

PloS one, 2011-02, Vol.6 (2), p.e16727

2011

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Regulation of pre-mRNA splicing: roles in physiology and disease, and therapeutic prospects

Nature reviews. Genetics, 2023-04, Vol.24 (4), p.251-269

2023

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The spliceosome as a target of novel antitumour drugs

Nature reviews. Drug discovery, 2012-11, Vol.11 (11), p.847-859

2012

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NeuN/Rbfox3 nuclear and cytoplasmic isoforms differentially regulate alternative splicing and nonsense-mediated decay of Rbfox2

PloS one, 2011-06, Vol.6 (6), p.e21585-e21585

2011

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Evolution of exon-intron structure and alternative splicing

PloS one, 2011-03, Vol.6 (3), p.e18055-e18055

2011

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Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

Cell, 2014-03, Vol.156 (6), p.1324-1335

2014

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The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches

EMBO reports, 2015-12, Vol.16 (12), p.1640-1655

2015

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Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes

PloS one, 2006-12, Vol.1 (1), p.e31-e31

2006

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Alternative splicing and genome complexity

Nature genetics, 2002-01, Vol.30 (1), p.29-30

2002

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Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

Genes & development, 2011-03, Vol.25 (5), p.445-459

2011

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Monitoring genomic sequences during SELEX using high-throughput sequencing: neutral SELEX

PloS one, 2010-02, Vol.5 (2), p.e9169-e9169

2010

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An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction

PloS one, 2010-09, Vol.5 (9), p.e13028

2010

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Minority report: The minor spliceosome as a novel cancer vulnerability factor

Molecular cell, 2023-06, Vol.83 (12), p.1958-1960

2023

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RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

Molecular cell, 2013-12, Vol.52 (5), p.720-733

2013

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Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor

PloS one, 2008-05, Vol.3 (5), p.e2097-e2097

2008

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Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors

PloS one, 2010-10, Vol.5 (10), p.e13690

2010

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Development of a single vector system that enhances trans-splicing of SMN2 transcripts

PloS one, 2008-10, Vol.3 (10), p.e3468-e3468

2008

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Splicing Calls Back

Cell, 2019-12, Vol.179 (7), p.1446-1447

2019

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Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells

PloS one, 2010-12, Vol.5 (12), p.e15884-e15884

2010

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Roles and mechanisms of alternative splicing in cancer - implications for care

MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia

Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types

The Spliceosome: The Ultimate RNA Chaperone and Sculptor

RNA-binding proteins in human genetic disease

Bridging the Gap: Assessing Material Performance of Laboratory Specimens and Concrete Structures

Histone deacetylase activity modulates alternative splicing

Regulation of pre-mRNA splicing: roles in physiology and disease, and therapeutic prospects

The spliceosome as a target of novel antitumour drugs

NeuN/Rbfox3 nuclear and cytoplasmic isoforms differentially regulate alternative splicing and nonsense-mediated decay of Rbfox2

Evolution of exon-intron structure and alternative splicing

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches

Human resistin is a systemic immune-derived proinflammatory cytokine targeting both leukocytes and adipocytes

Alternative splicing and genome complexity

Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

Monitoring genomic sequences during SELEX using high-throughput sequencing: neutral SELEX

An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction

Minority report: The minor spliceosome as a novel cancer vulnerability factor

RBM5, 6, and 10 Differentially Regulate NUMB Alternative Splicing to Control Cancer Cell Proliferation

Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor

Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors

Development of a single vector system that enhances trans-splicing of SMN2 transcripts

Splicing Calls Back

Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells

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