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Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca2+ uptake

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21731-21739

2020

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Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

Cell, 2010-07, Vol.142 (2), p.270-283

2010

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EMRE Is a Matrix Ca2+ Sensor that Governs Gatekeeping of the Mitochondrial Ca2+ Uniporter

Cell reports (Cambridge), 2016-01, Vol.14 (3), p.403-410

2016

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Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening

Molecular cell, 2017-08, Vol.67 (4), p.711-723.e7

2017

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Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20593-20598

2013

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ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

eLife, 2020-05, Vol.9

2020

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Apoptosis regulation by Bcl-xL modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12565-12570

2007

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Biphasic regulation of InsP₃ receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viability

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.E1953-E1962

2016

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Calpain-cleaved Type 1 Inositol 1,4,5-Trisphosphate Receptor (InsP3R1) Has InsP3-independent Gating and Disrupts Intracellular Ca2+ Homeostasis

The Journal of biological chemistry, 2011-10, Vol.286 (41), p.35998-36010

2011

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Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: implications for quartal Ca2+release

The Journal of physiology, 2006-06, Vol.573 (3), p.645-662

2006

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EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter

Cell reports (Cambridge), 2016-01, Vol.14 (3), p.403-410

2016

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Nuclear patch-clamp electrophysiology of Ca2+ channels

Cold Spring Harbor protocols, 2013-09, Vol.2013 (9), p.885

2013

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Patch-clamp electrophysiology of intracellular Ca2+ channels

Cold Spring Harbor protocols, 2013-09, Vol.2013 (9), p.787

2013

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MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter

Cell metabolism, 2015-10, Vol.22 (4), p.533-535

2015

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Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (35), p.21731-21739

2020

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Novel Luminal Regulation of Inositol 1,4,5-Trisphosphate Receptor Channel Gating

Biophysical journal, 2017-02, Vol.112 (3), p.232a-233a

2017

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The MCU Inhibitor Ds16570511 has Off-Target Effects on Mitochondrial Membrane Potential

Biophysical journal, 2019-02, Vol.116 (3), p.270a-270a

2019

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Matrix Ca2+Modulates Mitochondrial Uniporter (MCU) Activity by Flux-through Effects

Biophysical journal, 2019-02, Vol.116 (3), p.302a-303a

2019

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Biphasic regulation of InsP^sub 3^ receptor gating by dual Ca^sup 2+^ release channel BH3-like domains mediates Bcl-x^sub L^ control of cell viability

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.E1953

2016

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Biphasic regulation of InsP 3 receptor gating by dual Ca 2+ release channel BH3-like domains mediates Bcl-x L control of cell viability

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13)

2016

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A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

Cell, 2008-06, Vol.133 (7), p.1149-1161

2008

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Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (30), p.12565-12570

2007

Volltextzugriff (PDF)

General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening

Anesthesiology (Philadelphia), 2014-09, Vol.121 (3), p.528-537

2014

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ER-luminal Ca2+ regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

eLife, 2020-05, Vol.9

2020

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Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca2+ uptake

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

EMRE Is a Matrix Ca2+ Sensor that Governs Gatekeeping of the Mitochondrial Ca2+ Uniporter

Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening

Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors

ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

Apoptosis regulation by Bcl-xL modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating

Biphasic regulation of InsP₃ receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viability

Calpain-cleaved Type 1 Inositol 1,4,5-Trisphosphate Receptor (InsP3R1) Has InsP3-independent Gating and Disrupts Intracellular Ca2+ Homeostasis

Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: implications for quartal Ca2+release

EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter

Nuclear patch-clamp electrophysiology of Ca2+ channels

Patch-clamp electrophysiology of intracellular Ca2+ channels

MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter

Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca 2+ uptake

Novel Luminal Regulation of Inositol 1,4,5-Trisphosphate Receptor Channel Gating

The MCU Inhibitor Ds16570511 has Off-Target Effects on Mitochondrial Membrane Potential

Matrix Ca2+Modulates Mitochondrial Uniporter (MCU) Activity by Flux-through Effects

A recurrent missense variant in ITPR3 causes demyelinating Charcot-Marie-Tooth with variable severity

Biphasic regulation of InsP^sub 3^ receptor gating by dual Ca^sup 2+^ release channel BH3-like domains mediates Bcl-x^sub L^ control of cell viability

Biphasic regulation of InsP 3 receptor gating by dual Ca 2+ release channel BH3-like domains mediates Bcl-x L control of cell viability

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating

General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening

ER-luminal Ca2+ regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein

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