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JAK/STAT signaling in hematological malignancies

Oncogene, 2013-05, Vol.32 (21), p.2601-2613

2013

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The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

Leukemia, 2014-03, Vol.28 (3), p.485-496

2014

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MPL/JAK2: from one signaling pathway to several disorders

Leukemia research, 2016-05, Vol.44, p.S2-S2

Vainchenker, W

2016

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JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma

Leukemia, 2014-02, Vol.28 (2), p.338-348

2014

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Thrombopoietin receptor is required for the oncogenic function of CALR mutants

Leukemia, 2016-08, Vol.30 (8), p.1759-1763

2016

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Mutations of ASXL1 gene in myeloproliferative neoplasms

Leukemia, 2009-11, Vol.23 (11), p.2183-2186

2009

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Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin

Leukemia, 2016-08, Vol.30 (8), p.1775-1778

2016

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A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression

Leukemia, 2013-11, Vol.27 (11), p.2187-2195

2013

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JAK2 negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms

Oncogene, 2012-03, Vol.31 (10), p.1323-1333

2012

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From hematopoietic stem cells to platelets

Journal of thrombosis and haemostasis, 2007-07, Vol.5 (s1), p.318-327

2007

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Myelofibrosis, JAK2 inhibitors and erythropoiesis

Leukemia, 2013-06, Vol.27 (6), p.1219-1223

2013

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The cell division control protein 42–Src family kinase–neural Wiskott–Aldrich syndrome protein pathway regulates human proplatelet formation

Journal of thrombosis and haemostasis, 2016-12, Vol.14 (12), p.2524-2535

2016

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TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

Leukemia, 2009-05, Vol.23 (5), p.905-911

2009

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Regulation of megakaryocyte maturation and platelet formation

Journal of thrombosis and haemostasis, 2009-07, Vol.7, p.227-234

2009

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Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution

Leukemia, 2015-01, Vol.29 (1), p.249-252

2015

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Developmental changes in human megakaryopoiesis

Journal of thrombosis and haemostasis, 2013-09, Vol.11 (9), p.1730-1741

2013

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The abnormal proplatelet formation in MYH9‐related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition

Journal of thrombosis and haemostasis, 2013-12, Vol.11 (12), p.2163-2175

2013

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CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model

Cell death & disease, 2012-10, Vol.3 (10), p.e396-e396

2012

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Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens

Blood, 2006-11, Vol.108 (9), p.3012-3020

2006

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Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

Oncogene, 2015-03, Vol.34 (10), p.1323-1332

2015

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Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms

Cell death & disease, 2013-07, Vol.4 (7), p.e738-e738

2013

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Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling

Cell death and differentiation, 2011-04, Vol.18 (4), p.678-689

2011

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Oncogenic mechanisms in myeloproliferative disorders

Cellular and molecular life sciences : CMLS, 2006-12, Vol.63 (24), p.2939-2953

2006

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Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenotype in vitro

Cell death & disease, 2012-07, Vol.3 (7), p.e356-e356

2012

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JAK/STAT signaling in hematological malignancies

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

MPL/JAK2: from one signaling pathway to several disorders

JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma

Thrombopoietin receptor is required for the oncogenic function of CALR mutants

Mutations of ASXL1 gene in myeloproliferative neoplasms

Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin

A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression

JAK2 negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms

From hematopoietic stem cells to platelets

Myelofibrosis, JAK2 inhibitors and erythropoiesis

The cell division control protein 42–Src family kinase–neural Wiskott–Aldrich syndrome protein pathway regulates human proplatelet formation

TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

Regulation of megakaryocyte maturation and platelet formation

Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution

Developmental changes in human megakaryopoiesis

The abnormal proplatelet formation in MYH9‐related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition

STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model

CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model

Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens

Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms

Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling

Oncogenic mechanisms in myeloproliferative disorders

Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenotype in vitro

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