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Genotoxicity evaluation: Moving forward from qualitative to quantitative approaches

Toxicology letters, 2011-08, Vol.205, p.S8-S8

Thybaud, V.

2011

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Recommendations for conducting the in vivo alkaline Comet assay

Mutagenesis, 2003-01, Vol.18 (1), p.45-51

2003

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Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

Environmental and molecular mutagenesis, 2013-01, Vol.54 (1), p.8-18

2013

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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

Environmental and molecular mutagenesis, 2014-10, Vol.55 (8), p.609-623

2014

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Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides

Regulatory toxicology and pharmacology, 2018-04, Vol.94, p.172-182

2018

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Standardized cell sources and recommendations for good cell culture practices in genotoxicity testing

Mutation research, 2016-10, Vol.809, p.1-15

2016

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Strategy for genotoxicity testing: Hazard identification and risk assessment in relation to in vitro testing

Mutation research, 2007-02, Vol.627 (1), p.41-58

2007

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Existe-t-il une dose seuil pour les effets génotoxiques ?

Archives des maladies professionnelles et de l'environnement, 2012-09, Vol.73 (4), p.658-666

Thybaud, V.

2012

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Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative

Mutation research, 2007-10, Vol.633 (2), p.67-79

2007

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The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy

Bioorganic & medicinal chemistry, 2001-02, Vol.9 (2), p.537-554

2001

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Fourth International Workgroup on Genotoxicity testing: Results of the in vivo Comet assay workgroup

Mutation research, 2007-02, Vol.627 (1), p.31-35

2007

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In vivo transgenic mutation assays

Environmental and molecular mutagenesis, 2000, Vol.35 (3), p.253-259

2000

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SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study

Mutation research, 2006-08, Vol.607 (1), p.13-36

2006

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Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling

Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2007-06, Vol.619 (1), p.16-29

2007

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Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens

Mutagenesis, 1999, Vol.14 (1), p.141-151

1999

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SFTG international collaborative study on in vitro micronucleus test II. Using human lymphocytes

Mutation research, 2006-08, Vol.607 (1), p.37-60

2006

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In vivo transgenic mutation assays

Mutation research, 2003-10, Vol.540 (2), p.141-151

2003

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SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells

Mutation research, 2006-08, Vol.607 (1), p.61-87

2006

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SFTG international collaborative study on in vitro micronucleus test V. Using L5178Y cells

Mutation research, 2006-08, Vol.607 (1), p.125-152

2006

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Validation of the in vivo CD1 mouse splenocyte micronucleus test

Mutagenesis, 1994-05, Vol.9 (3), p.199-204

1994

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SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells

Mutation research, 2006-08, Vol.607 (1), p.88-124

2006

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Comparative evaluation of the in vitro micronucleus test and the in vitro chromosome aberration test: industrial experience

Mutation research, 1997-08, Vol.392 (1), p.45-59

1997

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Effect of mitogenic or regenerative cell proliferation on lacz mutant frequency in the liver of Muta™Mice treated with 5,9-dimethyldibenzo[c,g]carbazole

Carcinogenesis (New York), 1999-07, Vol.20 (7), p.1357-1362

1999

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Use of scanning cytometry in studying bradykinin binding in MRC-5 cells

Cell Biology and Toxicology [CELL BIOL. TOXICOL.]. Vol. 10, no. 5-6. 1994, 1994-12, Vol.10 (5-6), p.317-322

1994

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Genotoxicity evaluation: Moving forward from qualitative to quantitative approaches

Recommendations for conducting the in vivo alkaline Comet assay

Quantitative approaches for assessing dose-response relationships in genetic toxicology studies

Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment

Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides

Standardized cell sources and recommendations for good cell culture practices in genotoxicity testing

Strategy for genotoxicity testing: Hazard identification and risk assessment in relation to in vitro testing

Existe-t-il une dose seuil pour les effets génotoxiques ?

Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative

The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy

Fourth International Workgroup on Genotoxicity testing: Results of the in vivo Comet assay workgroup

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

In vivo transgenic mutation assays

SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study

Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling

Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens

SFTG international collaborative study on in vitro micronucleus test II. Using human lymphocytes

In vivo transgenic mutation assays

SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells

SFTG international collaborative study on in vitro micronucleus test V. Using L5178Y cells

Validation of the in vivo CD1 mouse splenocyte micronucleus test

SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells

Comparative evaluation of the in vitro micronucleus test and the in vitro chromosome aberration test: industrial experience

Effect of mitogenic or regenerative cell proliferation on lacz mutant frequency in the liver of Muta™Mice treated with 5,9-dimethyldibenzo[c,g]carbazole

Use of scanning cytometry in studying bradykinin binding in MRC-5 cells

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