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Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

eLife, 2018-06, Vol.7

2018

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Synergistic interactions of cytarabine-adavosertib in leukemic cell lines proliferation and metabolomic endpoints

Biomedicine & pharmacotherapy, 2023-10, Vol.166, p.115352-115352, Article 115352

2023

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Molecular Docking and Dynamics Simulation of Protein β-Tubulin and Antifungal Cyclic Lipopeptides

Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3387

2019

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Identification and In Silico Characterization of Novel Helicobacter pylori Glucose-6-Phosphate Dehydrogenase Inhibitors

Molecules (Basel, Switzerland), 2021-08, Vol.26 (16), p.4955

2021

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Antinociceptive effect of LMH-2, a new sigma-1 receptor antagonist analog of haloperidol, on the neuropathic pain of diabetic mice

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116524-116524, Article 116524

2024

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Parkinson's Disease Genetics and Pathophysiology

Annual review of neuroscience, 2021-07, Vol.44 (1), p.87-108

2021

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Synergistic Effects of Adavosertib, WEE‐1 Inhibitor in Combination with Cytarabine in the Jurkat Leukemia Cell Model

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Design of a multi-target focused library for antidiabetic targets using a comprehensive set of chemical transformation rules

Frontiers in pharmacology, 2023, Vol.14, p.1276444

2023

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Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs

European journal of medicinal chemistry, 2014-04, Vol.77, p.400-408

2014

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Tilianin obtained from Agastache mexicana inhibits monoamine oxidase and modifies depressive behavior in rats

Journal of pharmacy and pharmacology, 2024-10

2024

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Thermodynamic characterization of the inclusion complexes formation between antidiabetic new drugs and cyclodextrins

The Journal of chemical thermodynamics, 2019-02, Vol.129, p.55-60

2019

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Discovery of Palindrome Dual PPARγ-GPR40 Agonists for Treating Type 2 Diabetes

ChemMedChem, 2024-09, p.e202400492

2024

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Design, Synthesis and Biological Evaluation of 2-(2-Amino-5(6)-nitro-1H-benzimidazol-1-yl)-N-arylacetamides as Antiprotozoal Agents

Molecules (Basel, Switzerland), 2017-04, Vol.22 (4), p.579

2017

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Synthesis, molecular docking, dynamic simulation and pharmacological characterization of potent multifunctional agent (dual GPR40-PPARγ agonist) for the treatment of experimental type 2 diabetes

European journal of pharmacology, 2021-09, Vol.907, p.174244, Article 174244

2021

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Antidiabetic effect of Achillea millefollium through multitarget interactions: α-glucosidases inhibition, insulin sensitization and insulin secretagogue activities

Journal of ethnopharmacology, 2018-02, Vol.212, p.1-7

2018

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Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors

Molecules (Basel, Switzerland), 2023-05, Vol.28 (10), p.4180

2023

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Antihypertensive and vasorelaxant effect of leucodin and achillin isolated from Achillea millefolium through calcium channel blockade and NO production: In vivo, functional ex vivo and in silico studies

Journal of ethnopharmacology, 2021-06, Vol.273, p.113948-113948, Article 113948

2021

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Heart transplant experience after circulatory death. Are there differences with brain death?

Journal of critical care, 2024-06, Vol.81, p.154609, Article 154609

2024

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Heart transplants from controlled donation after the circulatory determination of death (CDD): Our initial experience

Journal of critical care, 2024-06, Vol.81, p.154588, Article 154588

2024

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Analysis of mortality associated with stanford type A aortic dissection at Cardiovascular Surgery Unit of the Intensive Care Unit at the Virgen de la Arrixaca University Hospital in Murcia, Spain

Journal of critical care, 2024-06, Vol.81, p.154611, Article 154611

2024

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Tracheal relaxation through calcium channel blockade of Achillea millefolium hexanic extract and its main bioactive compounds

Journal of ethnopharmacology, 2020-05, Vol.253, p.112643, Article 112643

2020

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Antidiabetic drugs in Parkinson’s disease

Clinical parkinsonism & related disorders, 2024-01, Vol.11, p.100265, Article 100265

2024

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N-(Benzothiazol-2-yl)-4-((5-chlorobenzoxazol-2-yl)amino)butanamide

MolBank, 2024-09, Vol.2024 (3), p.M1854

2024

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Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study

Biomedicine & pharmacotherapy, 2018-11, Vol.107, p.1302-1310

2018

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PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice

Canadian journal of physiology and pharmacology, 2022-04, Vol.100 (4), p.295-305

2022

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Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

Synergistic interactions of cytarabine-adavosertib in leukemic cell lines proliferation and metabolomic endpoints

Molecular Docking and Dynamics Simulation of Protein β-Tubulin and Antifungal Cyclic Lipopeptides

Identification and In Silico Characterization of Novel Helicobacter pylori Glucose-6-Phosphate Dehydrogenase Inhibitors

Antinociceptive effect of LMH-2, a new sigma-1 receptor antagonist analog of haloperidol, on the neuropathic pain of diabetic mice

Parkinson's Disease Genetics and Pathophysiology

Synergistic Effects of Adavosertib, WEE‐1 Inhibitor in Combination with Cytarabine in the Jurkat Leukemia Cell Model

Design of a multi-target focused library for antidiabetic targets using a comprehensive set of chemical transformation rules

Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs

Tilianin obtained from Agastache mexicana inhibits monoamine oxidase and modifies depressive behavior in rats

Thermodynamic characterization of the inclusion complexes formation between antidiabetic new drugs and cyclodextrins

Discovery of Palindrome Dual PPARγ-GPR40 Agonists for Treating Type 2 Diabetes

Design, Synthesis and Biological Evaluation of 2-(2-Amino-5(6)-nitro-1H-benzimidazol-1-yl)-N-arylacetamides as Antiprotozoal Agents

Synthesis, molecular docking, dynamic simulation and pharmacological characterization of potent multifunctional agent (dual GPR40-PPARγ agonist) for the treatment of experimental type 2 diabetes

Antidiabetic effect of Achillea millefollium through multitarget interactions: α-glucosidases inhibition, insulin sensitization and insulin secretagogue activities

Synthesis and Molecular Docking Studies of Alkoxy- and Imidazole-Substituted Xanthones as α-Amylase and α-Glucosidase Inhibitors

Antihypertensive and vasorelaxant effect of leucodin and achillin isolated from Achillea millefolium through calcium channel blockade and NO production: In vivo, functional ex vivo and in silico studies

Heart transplant experience after circulatory death. Are there differences with brain death?

Heart transplants from controlled donation after the circulatory determination of death (CDD): Our initial experience

Analysis of mortality associated with stanford type A aortic dissection at Cardiovascular Surgery Unit of the Intensive Care Unit at the Virgen de la Arrixaca University Hospital in Murcia, Spain

Tracheal relaxation through calcium channel blockade of Achillea millefolium hexanic extract and its main bioactive compounds

Antidiabetic drugs in Parkinson’s disease

N-(Benzothiazol-2-yl)-4-((5-chlorobenzoxazol-2-yl)amino)butanamide

Synthesis and evaluation of thiazolidine-2,4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular docking study

PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice

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