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Antidepressant-like responses to the combined sigma and 5-HT1A receptor agonist OPC-14523

Neuropharmacology, 2001-12, Vol.41 (8), p.976-988

2001

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Mechanism of Action of Aripiprazole Predicts Clinical Efficacy and a Favourable Side-Effect Profile

Journal of psychopharmacology (Oxford), 2004-09, Vol.18 (3), p.375-383

2004

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Antidepressant-like responses to the combined sigma and 5-HT1A receptor agonist OPC-14523

Neuropharmacology, 2001-12, Vol.41 (8), p.976-988

2001

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3,4-Dihydro-2(1H)-quinolinone as a Novel Antidepressant Drug: Synthesis and Pharmacology of 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-3,4- dihydro-5-methoxy-2(1H)-quinolinone and Its Derivatives

Journal of medicinal chemistry, 2000-01, Vol.43 (2), p.177-189

2000

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Novel Antipsychotic Agents with Dopamine Autoreceptor Agonist Properties: Synthesis and Pharmacology of 7-[4-(4-Phenyl-1-piperazinyl)butoxy]-3,4-dihydro-2(1H)-quinolinone Derivatives

Journal of medicinal chemistry, 1998-02, Vol.41 (5), p.658-667

1998

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The attenuating effect of carteolol hydrochloride, a β-adrenoceptor antagonist, on neuroleptic induced catalepsy in rats

Psychopharmacologia, 1997-05, Vol.131 (2), p.108-114

1997

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Diminished catalepsy and dopamine metabolism distinguish aripiprazole from haloperidol or risperidone

European journal of pharmacology, 2003-07, Vol.472 (1), p.89-97

2003

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7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity

The Journal of pharmacology and experimental therapeutics, 1995-07, Vol.274 (1), p.329

1995

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Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate)

The Journal of pharmacology and experimental therapeutics, 2002-04, Vol.301 (1), p.249

2002

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Effects of antioxidant, OPC-14117, on secondary cellular damage and behavioral deficits following cortical contusion in the rat

Brain research, 2002-05, Vol.934 (2), p.117-124

2002

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Antidepressant-like responses to the combined sigma and 5-HT 1A receptor agonist OPC-14523

Neuropharmacology, 2001, Vol.41 (8), p.976-988

2001

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Antidepressant-like responses to the combined sigma and 5-HT sub(1A) receptor agonist OPC-14523

Neuropharmacology, 2001-12, Vol.41 (8), p.976-988

2001

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Antioxidant, OPC-14117, attenuates edema formation and behavioral deficits following cortical contusion in rats

Acta neurochirurgica. Supplement, 1997, Vol.70, p.191

1997

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Antioxidant, OPC-14117, attenuates edema formation, and subsequent tissue damage following cortical contusion in rats

Acta neurochirurgica. Supplement, 1998, Vol.71, p.120

1998

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Evaluation of learning and memory dysfunction and histological findings in rats with chronic stage contusion and diffuse axonal injury

Brain research, 1997-03, Vol.752 (1), p.151-160

1997

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Behavioral studies of OPC-14597, a novel antipsychotic drug

European neuropsychopharmacology, 1996-06, Vol.6, p.106-106

1996

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Pharmacological profile of OPC-14523 (2): Effects on learning and memory impairment

European neuropsychopharmacology, 1996-06, Vol.6, p.189-189

1996

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Pharmacological profile of OPC-14523 (1): A novel sigma and 5-HT1A receptor agonist

European neuropsychopharmacology, 1996-06, Vol.6, p.190

1996

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Effects of OPC-14117 on dopaminergic neuronal degeneration induced by MPTP

European neuropsychopharmacology, 1996-06, Vol.6, p.132-132

1996

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Cognitive dysfunction and histological findings in rats with chronic-stage contusion and diffuse axonal injury

Brain research. Brain research protocols, 1998-09, Vol.3 (1), p.100-106

1998

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Pharmacological profile of OPC-14523 (1): A novel sigma and 5-HT 1A receptor agonist

European neuropsychopharmacology, 1996, Vol.6, p.190-190

1996

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ChemInform Abstract: Novel Antipsychotic Agents with Dopamine Autoreceptor Agonist Properties: Synthesis and Pharmacology of 7-[4-(4-Phenyl-1-piperazinyl)butoxy]-3,4-dihydro-2(1H)-quinolinone Derivatives

ChemInform, 1998-07, Vol.29 (27), p.no-no

1998

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P-853 - PHARMACOLOGICAL PROFILE OF OPC-14523 (2) : EFFECTS ON LEARNING AND MEMORY IMPAIRMENT

Japanese journal of pharmacology, 1996, Vol.71, p.272-272

1996

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PHARMACOLOGICAL PROFILE OF OPC-14523 (2) : EFFECTS ON LEARNING AND MEMORY IMPAIRMENT

Japanese journal of pharmacology, 1996, Vol.71, p.272

1996

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PHARMACOLOGICAL PROFILE OF OPC-14523

Japanese Journal of Pharmacology, 1996, Vol.71 (suppl.2), p.272-272

1996

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Antidepressant-like responses to the combined sigma and 5-HT1A receptor agonist OPC-14523

Mechanism of Action of Aripiprazole Predicts Clinical Efficacy and a Favourable Side-Effect Profile

Antidepressant-like responses to the combined sigma and 5-HT1A receptor agonist OPC-14523

3,4-Dihydro-2(1H)-quinolinone as a Novel Antidepressant Drug: Synthesis and Pharmacology of 1-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-3,4- dihydro-5-methoxy-2(1H)-quinolinone and Its Derivatives

Novel Antipsychotic Agents with Dopamine Autoreceptor Agonist Properties: Synthesis and Pharmacology of 7-[4-(4-Phenyl-1-piperazinyl)butoxy]-3,4-dihydro-2(1H)-quinolinone Derivatives

The attenuating effect of carteolol hydrochloride, a β-adrenoceptor antagonist, on neuroleptic induced catalepsy in rats

Diminished catalepsy and dopamine metabolism distinguish aripiprazole from haloperidol or risperidone

7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity

Attenuation of scopolamine-induced and age-associated memory impairments by the sigma and 5-hydroxytryptamine(1A) receptor agonist OPC-14523 (1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2[1H]-quinolinone monomethanesulfonate)

Effects of antioxidant, OPC-14117, on secondary cellular damage and behavioral deficits following cortical contusion in the rat

Antidepressant-like responses to the combined sigma and 5-HT 1A receptor agonist OPC-14523

Antidepressant-like responses to the combined sigma and 5-HT sub(1A) receptor agonist OPC-14523

Antioxidant, OPC-14117, attenuates edema formation and behavioral deficits following cortical contusion in rats

Antioxidant, OPC-14117, attenuates edema formation, and subsequent tissue damage following cortical contusion in rats

Evaluation of learning and memory dysfunction and histological findings in rats with chronic stage contusion and diffuse axonal injury

Behavioral studies of OPC-14597, a novel antipsychotic drug

Pharmacological profile of OPC-14523 (2): Effects on learning and memory impairment

Pharmacological profile of OPC-14523 (1): A novel sigma and 5-HT1A receptor agonist

Effects of OPC-14117 on dopaminergic neuronal degeneration induced by MPTP

Cognitive dysfunction and histological findings in rats with chronic-stage contusion and diffuse axonal injury

Pharmacological profile of OPC-14523 (1): A novel sigma and 5-HT 1A receptor agonist

ChemInform Abstract: Novel Antipsychotic Agents with Dopamine Autoreceptor Agonist Properties: Synthesis and Pharmacology of 7-[4-(4-Phenyl-1-piperazinyl)butoxy]-3,4-dihydro-2(1H)-quinolinone Derivatives

P-853 - PHARMACOLOGICAL PROFILE OF OPC-14523 (2) : EFFECTS ON LEARNING AND MEMORY IMPAIRMENT

PHARMACOLOGICAL PROFILE OF OPC-14523 (2) : EFFECTS ON LEARNING AND MEMORY IMPAIRMENT

PHARMACOLOGICAL PROFILE OF OPC-14523

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