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HIV Infects Bronchial Epithelium and Suppresses Components of the Mucociliary Clearance Apparatus

PloS one, 2017-01, Vol.12 (1), p.e0169161-e0169161

2017

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Gene-specific MicroRNA antagonism protects against HIV Tat and TGF-β-mediated suppression of CFTR mRNA and function

Biomedicine & pharmacotherapy, 2021-10, Vol.142, p.112090-112090, Article 112090

2021

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TGF-β1 increases viral burden and promotes HIV-1 latency in primary differentiated human bronchial epithelial cells

Scientific reports, 2019-08, Vol.9 (1), p.12552-10, Article 12552

2019

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Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function

Scientific reports, 2018-05, Vol.8 (1), p.7984-10, Article 7984

2018

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Novel Approaches of CRISPR-Cas Technology in Airway Diseases

Critical reviews in biomedical engineering, 2020, Vol.48 (3), p.169-176

2020

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Inhibition of HIV-1 gene expression by novel macrophage-tropic DNA enzymes targeted to cleave HIV-1 TAT/Rev RNA

Biochemical journal, 2001-07, Vol.357 (Pt 1), p.147-155

2001

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C73 NEW MECHANISMS AND THERAPIES IN COPD: Tgf-Beta Suppresses Cftr Biogenesis And Function By Post-Transcriptional Gene Silencing

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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A27 HIV AND THE LUNG: Hiv Proteins Tat And Gp120 Promote Oxidative Stress And Suppress Components Of The Mucociliary Clearance Apparatus

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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C34 MECHANISMS OF HOST DEFENSE IN BACTERIAL AND FUNGAL INFECTIONS: Cigarette Smoke Enhances Hiv-1 Infection Of Nhbe Cells And Suppresses Cftr Function

American journal of respiratory and critical care medicine, 2017-01, Vol.195

2017

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B61 POTPOURRI OF INJ-OURRI: EPITHELIAL CELLS IN LUNG INJURY AND REPAIR: Hydrogen Peroxide Mediated Decreases In Epithelial Barrier Function Depend On Multiple Signaling Pathways

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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B61 POTPOURRI OF INJ-OURRI: EPITHELIAL CELLS IN LUNG INJURY AND REPAIR: Cigarette Smoke And Tgf-Beta1 Suppress The Ability Of Cftr Activators To Enhance Epithelial Permeability

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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Genetic analyses of the promoter region of interleukin-10 gene in different species of monkeys: implications for HIV/AIDS progression

Genes and immunity, 2001-11, Vol.2 (7), p.404-407

2001

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Potent knock down of HIV-1 replication by targeting HIV-1 Tat/Rev RNA sequences synergistically with catalytic RNA and DNA

AIDS (London), 2007-01, Vol.21 (1), p.31-40

2007

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Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA

Nature biotechnology, 2004-12, Vol.22 (12), p.1573-1578

2004

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Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-Inducible Coexpression of a Short Hairpin RNA and Protein

Journal of Virology, 2006-02, Vol.80 (4), p.1863-1873

2006

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Potent inhibition of HIV-1 gene expression and TAT-mediated apoptosis in human T cells by novel mono- and multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme

Antiviral research, 2006-11, Vol.72 (2), p.134-144

2006

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Novel mono- and di-DNA-enzymes targeted to cleave TAT or TAT-REV RNA inhibit HIV-1 gene expression

Antiviral research, 2001-08, Vol.51 (2), p.127-139

2001

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Genetic analyses of cis-acting sequences controlling expression of human immunodeficiency virus type 1 coreceptor-CCR5 gene in rabbits and CXCR4 gene in monkeys

Journal of human virology, 2001-07, Vol.4 (4), p.188

2001

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Targeted cleavage of HIV-1 envelope gene by a DNA enzyme and inhibition of HIV-1 envelope-CD4 mediated cell fusion

FEBS letters, 1998-07, Vol.431 (3), p.395-399

1998

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MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation

Journal of inflammation (London, England), 2024-08, Vol.21 (1), p.31-14

2024

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Identification of N‑{cis-3-[Methyl(7H‑pyrrolo[2,3‑d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.1130-1152

2018

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Structure-Based Design of Estrogen Receptor-β Selective Ligands

Journal of the American Chemical Society, 2004-11, Vol.126 (46), p.15106-15119

2004

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Design, Synthesis, and Preclinical Characterization of Novel, Highly Selective Indole Estrogens

Journal of medicinal chemistry, 2001-05, Vol.44 (11), p.1654-1657

2001

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Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (12), p.3137-3142

2005

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Insights for Predicting Blood-Brain Barrier Penetration of CNS Targeted Molecules Using QSPR Approaches

Journal of chemical information and modeling, 2010-06, Vol.50 (6), p.1123-1133

2010

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HIV Infects Bronchial Epithelium and Suppresses Components of the Mucociliary Clearance Apparatus

Gene-specific MicroRNA antagonism protects against HIV Tat and TGF-β-mediated suppression of CFTR mRNA and function

TGF-β1 increases viral burden and promotes HIV-1 latency in primary differentiated human bronchial epithelial cells

Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function

Novel Approaches of CRISPR-Cas Technology in Airway Diseases

Inhibition of HIV-1 gene expression by novel macrophage-tropic DNA enzymes targeted to cleave HIV-1 TAT/Rev RNA

C73 NEW MECHANISMS AND THERAPIES IN COPD: Tgf-Beta Suppresses Cftr Biogenesis And Function By Post-Transcriptional Gene Silencing

A27 HIV AND THE LUNG: Hiv Proteins Tat And Gp120 Promote Oxidative Stress And Suppress Components Of The Mucociliary Clearance Apparatus

C34 MECHANISMS OF HOST DEFENSE IN BACTERIAL AND FUNGAL INFECTIONS: Cigarette Smoke Enhances Hiv-1 Infection Of Nhbe Cells And Suppresses Cftr Function

B61 POTPOURRI OF INJ-OURRI: EPITHELIAL CELLS IN LUNG INJURY AND REPAIR: Hydrogen Peroxide Mediated Decreases In Epithelial Barrier Function Depend On Multiple Signaling Pathways

B61 POTPOURRI OF INJ-OURRI: EPITHELIAL CELLS IN LUNG INJURY AND REPAIR: Cigarette Smoke And Tgf-Beta1 Suppress The Ability Of Cftr Activators To Enhance Epithelial Permeability

Genetic analyses of the promoter region of interleukin-10 gene in different species of monkeys: implications for HIV/AIDS progression

Potent knock down of HIV-1 replication by targeting HIV-1 Tat/Rev RNA sequences synergistically with catalytic RNA and DNA

Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA

Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-Inducible Coexpression of a Short Hairpin RNA and Protein

Potent inhibition of HIV-1 gene expression and TAT-mediated apoptosis in human T cells by novel mono- and multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme

Novel mono- and di-DNA-enzymes targeted to cleave TAT or TAT-REV RNA inhibit HIV-1 gene expression

Genetic analyses of cis-acting sequences controlling expression of human immunodeficiency virus type 1 coreceptor-CCR5 gene in rabbits and CXCR4 gene in monkeys

Targeted cleavage of HIV-1 envelope gene by a DNA enzyme and inhibition of HIV-1 envelope-CD4 mediated cell fusion

MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation

Identification of N‑{cis-3-[Methyl(7H‑pyrrolo[2,3‑d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases

Structure-Based Design of Estrogen Receptor-β Selective Ligands

Design, Synthesis, and Preclinical Characterization of Novel, Highly Selective Indole Estrogens

Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones

Insights for Predicting Blood-Brain Barrier Penetration of CNS Targeted Molecules Using QSPR Approaches

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