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Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

Journal of Virology, 2012-03, Vol.86 (5), p.2696-2705

2012

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Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4552-4559

2011

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Antiviral characteristics of GSK1265744, an HIV integrase inhibitor dosed orally or by long-acting injection

Antimicrobial agents and chemotherapy, 2015-01, Vol.59 (1), p.397-406

2015

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Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

PloS one, 2013-10, Vol.8 (10), p.e77448

2013

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Dolutegravir/lamivudine as a first-line regimen in a test-and-treat setting for newly diagnosed people living with HIV

AIDS (London), 2021-10, Vol.35 (12), p.1957-1965

2021

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In Vitro Activities of Benzimidazole d- and l-Ribonucleosides against Herpesviruses

Antimicrobial Agents and Chemotherapy, 2003-07, Vol.47 (7), p.2186-2192

2003

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The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Antimicrobial Agents and Chemotherapy, 2008-03, Vol.52 (3), p.901-908

2008

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The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults

Journal of acquired immune deficiency syndromes (1999), 2012-11, Vol.61 (3), p.297

2012

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Effects of raltegravir or elvitegravir resistance signature mutations on the barrier to dolutegravir resistance in vitro

Antimicrobial agents and chemotherapy, 2015-05, Vol.59 (5), p.2596-2606

2015

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Mechanism of Action of the Ribopyranoside Benzimidazole GW275175X against Human Cytomegalovirus

Antimicrobial Agents and Chemotherapy, 2004-05, Vol.48 (5), p.1647-1651

2004

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Sustained Virologic Suppression With Dolutegravir/Lamivudine in a Test-and-Treat Setting Through 48 Weeks

Open forum infectious diseases, 2023-03, Vol.10 (3), p.ofad101-ofad101

2023

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The Cys607→Tyr Change in the UL97 Phosphotransferase Confers Ganciclovir Resistance to Two Human Cytomegalovirus Strains Recovered from Two Immunocompromised Patients

Antimicrobial Agents and Chemotherapy, 1998-02, Vol.42 (2), p.444-446

1998

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Secondary mutations in viruses resistant to HIV-1 integrase inhibitors that restore viral infectivity and replication kinetics

Antiviral research, 2009-02, Vol.81 (2), p.141-146

2009

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Identification of Peptides That Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein

Journal of Virology, 2004-03, Vol.78 (5), p.2637-2641

2004

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Resistance of Human Cytomegalovirus to Benzimidazole Ribonucleosides Maps to Two Open Reading Frames: UL89 and UL56

Journal of Virology, 1998-06, Vol.72 (6), p.4721-4728

1998

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Inhibition of Human Cytomegalovirus DNA Maturation by a Benzimidazole Ribonucleoside Is Mediated through the UL89 Gene Product

Journal of Virology, 1998-01, Vol.72 (1), p.717-725

1998

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Sensitivity of Phenotypic Susceptibility Analyses for Nonthymidine Nucleoside Analogues Conferred by K65R or M184V in Mixtures with Wild-Type HIV-1

The Journal of infectious diseases, 2009-01, Vol.199 (1), p.84-88

2009

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Differential impact of thymidine analogue mutations on emtricitabine and lamivudine susceptibility

Journal of acquired immune deficiency syndromes (1999), 2006-12, Vol.43 (5), p.567

2006

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The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Antimicrobial agents and chemotherapy, 2008-05, Vol.52 (5), p.1899-1899

2008

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Groundwater lens dynamics of Atoll Islands

Water resources research, 1992-11, Vol.28 (11), p.2889-2902

1992

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Searching for antiviral drugs for human papillomaviruses

Antiviral therapy, 2000-12, Vol.5 (4), p.229-242

2000

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Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS

Journal of Virology, 1996-03, Vol.70 (3), p.1390-1395

1996

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Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics: e77448

PloS one, 2013-10, Vol.8 (10)

2013

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Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29

The EMBO journal, 1990-01, Vol.9 (1), p.91-99

1990

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Differences in DNA Packaging Genes and Sensitivity to Benzimidazole Ribonucleosides between Human Cytomegalovirus Strains AD169 and Towne

Antiviral chemistry & chemotherapy, 2000-09, Vol.11 (5), p.349-352

2000

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Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Antiviral characteristics of GSK1265744, an HIV integrase inhibitor dosed orally or by long-acting injection

Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

Dolutegravir/lamivudine as a first-line regimen in a test-and-treat setting for newly diagnosed people living with HIV

In Vitro Activities of Benzimidazole d- and l-Ribonucleosides against Herpesviruses

The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

The activity of the integrase inhibitor dolutegravir against HIV-1 variants isolated from raltegravir-treated adults

Effects of raltegravir or elvitegravir resistance signature mutations on the barrier to dolutegravir resistance in vitro

Mechanism of Action of the Ribopyranoside Benzimidazole GW275175X against Human Cytomegalovirus

Sustained Virologic Suppression With Dolutegravir/Lamivudine in a Test-and-Treat Setting Through 48 Weeks

The Cys607→Tyr Change in the UL97 Phosphotransferase Confers Ganciclovir Resistance to Two Human Cytomegalovirus Strains Recovered from Two Immunocompromised Patients

Secondary mutations in viruses resistant to HIV-1 integrase inhibitors that restore viral infectivity and replication kinetics

Identification of Peptides That Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein

Resistance of Human Cytomegalovirus to Benzimidazole Ribonucleosides Maps to Two Open Reading Frames: UL89 and UL56

Inhibition of Human Cytomegalovirus DNA Maturation by a Benzimidazole Ribonucleoside Is Mediated through the UL89 Gene Product

Sensitivity of Phenotypic Susceptibility Analyses for Nonthymidine Nucleoside Analogues Conferred by K65R or M184V in Mixtures with Wild-Type HIV-1

Differential impact of thymidine analogue mutations on emtricitabine and lamivudine susceptibility

The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Groundwater lens dynamics of Atoll Islands

Searching for antiviral drugs for human papillomaviruses

Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics: e77448

Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29

Differences in DNA Packaging Genes and Sensitivity to Benzimidazole Ribonucleosides between Human Cytomegalovirus Strains AD169 and Towne

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