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The manufacturing considerations of bispecific antibodies

Expert opinion on biological therapy, 2022-08, Vol.22 (8), p.1043-1065

2022

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Photochemically Enhanced Binding of Small Molecules to the Tumor Necrosis Factor Receptor-1 Inhibits the Binding of TNF-α

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (21), p.11879-11884

2001

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Chemical Similarity Using Geometric Atom Pair Descriptors

Journal of Chemical Information and Computer Sciences, 1996-01, Vol.36 (1), p.128-136

1996

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Discovery informatics: its evolving role in drug discovery

Drug Discovery Today, 2002-09, Vol.7 (18), p.957-966

2002

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Synthesis and Biological Activities of Potent Peptidomimetics Selective for Somatostatin Receptor Subtype 2

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (18), p.10836-10841

1998

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Effects of Heterocyclic Aromatic Substituents on Binding Affinities at Two Distinct Sites of Somatostatin Receptors. Correlation with the Electrostatic Potential of the Substituents

Journal of medicinal chemistry, 2003-05, Vol.46 (10), p.1858-1869

2003

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FLOG: A system to select ?quasi-flexible? ligands complementary to a receptor of known three-dimensional structure

Journal of computer-aided molecular design, 1994-04, Vol.8 (2), p.153-174

1994

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Synthesis of a Substance P Antagonist with a Somatostatin Scaffold: Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry

Journal of medicinal chemistry, 2000-10, Vol.43 (21), p.3827-3831

2000

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Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide Analogs (∗)

The Journal of biological chemistry, 1995-07, Vol.270 (27), p.15966-15969

1995

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Triangular platinum and nickel clusters: the "tinker-toy" construction of chains with high nuclearity

Journal of the American Chemical Society, 1985-10, Vol.107 (21), p.5968-5980

1985

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Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides

Journal of medicinal chemistry, 1990-09, Vol.33 (9), p.2522-2528

1990

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A Combinatorial Approach toward the Discovery of Non-Peptide, Subtype-Selective Somatostatin Receptor Ligands

Journal of combinatorial chemistry, 1999-09, Vol.1 (5), p.388-396

1999

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Finite and infinite ribbons: from platinum alkyne complexes to extended structures of the dipotassium diarsenoplatinate (K2PtAs2) type

Journal of the American Chemical Society, 1984-05, Vol.106 (10), p.2837-2847

1984

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Is the McLafferty rearrangement of ketones concerted or stepwise? The application of kinetic isotope effects

Organic Mass Spectrometry, 1992-03, Vol.27 (3), p.270-276

1992

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Flexibases: a way to enhance the use of molecular docking methods

Journal of computer-aided molecular design, 1994-10, Vol.8 (5), p.565-582

1994

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Is the collision induced loss of ethene from the (M - H+)− ion of butyrophenone a γ-hydrogen rearrangement?

Canadian journal of chemistry, 1986-04, Vol.64 (4), p.764-768

1986

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Orally Active .beta.-Lactam Inhibitors of Human Leukocyte Elastase. 3. Stereospecific Synthesis and Structure-Activity Relationships for 3,3-Dialkylazetidin-2-ones

Journal of medicinal chemistry, 1995-06, Vol.38 (13), p.2449-2462

1995

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Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptor

Chemistry & biology, 1994-12, Vol.1 (4), p.211-221

1994

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Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

Journal of medicinal chemistry, 1992-10, Vol.35 (21), p.3745-3754

1992

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Derivation of a 3D pharmacophore model for the angiotensin-II site one receptor

Journal of computer-aided molecular design, 1994-10, Vol.8 (5), p.491-512

1994

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[19] Advances in automated docking applied to human immunodeficiency virus type 1 protease

Methods in Enzymology, 1994, Vol.241, p.354,IN15,367-366,IN16,370

1994

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Benzyne and related systems: an ab initio molecular orbital approach

Pure and applied chemistry, 1986-01, Vol.58 (1), p.75-88

1986

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Finite and infinite ribbons: from platinum alkyne complexes to extended structures of the K2PtAs2 type

Journal of the American Chemical Society, 1984, Vol.106 (10), p.2837-2847

1984

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Teaching at the Trusty Camp

The Humanist educator, 1977-12, Vol.16 (2), p.96-96

Underwood, Dennis J.

1977

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Getting it together: signal transduction in G-protein coupled receptors by association of receptor domains

Chemistry & biology, 1997-04, Vol.4 (4), p.239-248

1997

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The manufacturing considerations of bispecific antibodies

Photochemically Enhanced Binding of Small Molecules to the Tumor Necrosis Factor Receptor-1 Inhibits the Binding of TNF-α

Chemical Similarity Using Geometric Atom Pair Descriptors

Discovery informatics: its evolving role in drug discovery

Synthesis and Biological Activities of Potent Peptidomimetics Selective for Somatostatin Receptor Subtype 2

Effects of Heterocyclic Aromatic Substituents on Binding Affinities at Two Distinct Sites of Somatostatin Receptors. Correlation with the Electrostatic Potential of the Substituents

FLOG: A system to select ?quasi-flexible? ligands complementary to a receptor of known three-dimensional structure

Synthesis of a Substance P Antagonist with a Somatostatin Scaffold: Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry

Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide Analogs (∗)

Triangular platinum and nickel clusters: the "tinker-toy" construction of chains with high nuclearity

Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides

A Combinatorial Approach toward the Discovery of Non-Peptide, Subtype-Selective Somatostatin Receptor Ligands

Finite and infinite ribbons: from platinum alkyne complexes to extended structures of the dipotassium diarsenoplatinate (K2PtAs2) type

Is the McLafferty rearrangement of ketones concerted or stepwise? The application of kinetic isotope effects

Flexibases: a way to enhance the use of molecular docking methods

Is the collision induced loss of ethene from the (M - H+)− ion of butyrophenone a γ-hydrogen rearrangement?

Orally Active .beta.-Lactam Inhibitors of Human Leukocyte Elastase. 3. Stereospecific Synthesis and Structure-Activity Relationships for 3,3-Dialkylazetidin-2-ones

Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptor

Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones

Derivation of a 3D pharmacophore model for the angiotensin-II site one receptor

[19] Advances in automated docking applied to human immunodeficiency virus type 1 protease

Benzyne and related systems: an ab initio molecular orbital approach

Finite and infinite ribbons: from platinum alkyne complexes to extended structures of the K2PtAs2 type

Teaching at the Trusty Camp

Getting it together: signal transduction in G-protein coupled receptors by association of receptor domains

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