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Characterization of compound A, a novel lincomycin derivative active against methicillin-resistant Staphylococcus aureus

Journal of antibiotics, 2021-02, Vol.74 (2), p.124-132

2021

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Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives

Journal of antibiotics, 2017-05, Vol.70 (5), p.655-663

2017

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Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines

Journal of antibiotics, 2016-06, Vol.69 (6), p.440-445

2016

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Synthesis and antibacterial activity of novel lincomycin derivatives. IV. Optimization of an N-6 substituent

Journal of antibiotics, 2017-12, Vol.70 (12), p.1112-1121

2017

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Synthesis and antibacterial activity of 1-N-[(S)-ω-amino-2-hydroxyalkyl] derivatives of dibekacin, 5-deoxydibekacin, 3'-deoxykanamycin A and gentamicin B

Journal of antibiotics, 2015-06, Vol.68 (6), p.421-423

2015

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Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety

Journal of antibiotics, 2018-01, Vol.71 (1), p.104-112

2018

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Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities

Journal of antibiotics, 2017-08, Vol.70 (8), p.888-906

2017

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Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs

Journal of antibiotics, 2017-01, Vol.70 (1), p.52-64

2017

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Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities

Journal of antibiotics, 2013-03, Vol.66 (3), p.195-198

2013

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Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity

Journal of antibiotics, 2018-02, Vol.71 (2), p.345-347

2018

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Aprosamine Derivatives Active against Multidrug-Resistant Gram-Negative Bacteria

ACS infectious diseases, 2023-04, Vol.9 (4), p.886-898

2023

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Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification

Journal of antibiotics, 2016-05, Vol.69 (5), p.368-380

2016

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Synthesis and antibacterial activity of 1-N-[(S)-[omega]-amino-2-hydroxyalkyl] derivatives of dibekacin, 5-deoxydibekacin, 3[variant prime]-deoxykanamycin A and gentamicin B

Journal of antibiotics, 2015-06, Vol.68 (6), p.421

2015

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Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA

Journal of antibiotics, 2016-06, Vol.69 (6), p.428-439

2016

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SYNTHESIS OF 1-N-(D-THREO-AND RACEMIC ERYTHRO-3-AMINO2-HYDROXYBUTANOYL)-2', 3'-DIDEOXYKANAMYCIN A

The Journal of Antibiotics, 1988/04/25, Vol.41(4), pp.530-537

1988

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SYNTHESIS OF 6''-CHLORO-6''-DEOXYAMIKACIN AND SOME ITS ANALOGS

The Journal of Antibiotics, 1990/12/25, Vol.43(12), pp.1611-1614

1990

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CP6679, a new injectable cephalosporin. Part1: Synthesis and structure–activity relationships

Bioorganic & medicinal chemistry, 2000, Vol.8 (12), p.2781-2789

2000

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Synthesis of 5-deoxy-5-epifluoro derivatives of arbekacin, amikacin, and 1- N-[( S)-4-amino-2-hydroxybutanoyl]tobramycin (study on structure — toxicity relationships)

Carbohydrate research, 1995-10, Vol.276 (1), p.75-89

1995

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Modification of Aminocyclitol Antibiotics. 6. Preparation of 5-Deoxykanamycin B

Bulletin of the Chemical Society of Japan, 1978-08, Vol.51 (8), p.2354-2357

1978

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CP6679, a new injectable cephalosporin. Part 1: Synthesis and structure-activity relationships

Bioorganic & medicinal chemistry, 2000-12, Vol.8 (12), p.2781-2789

2000

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Novel cephalosporin derivatives possessing a bicyclic heterocycle at the 3-position. Part II: Synthesis and antibacterial activity of 3-(5-methylthiazolo[4,5-c]pyridinium-2-yl)-thiomethylcephalosporin derivatives and related compounds

Bioorganic & medicinal chemistry, 1998-09, Vol.6 (9), p.1641-1653

1998

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A synthetic study of methyl 3-deoxy-3-fluoro-α- d-glucopyranosides from methyl 2,3-anhydro-α- d-allopyranosides, and synthesis of 3′-deoxy-3′-fluorokanamycin A and 3′-chloro-3′-deoxykanamycin A

Carbohydrate research, 1992-02, Vol.224, p.141-163

1992

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Synthesis of 5-deoxy-5-fluoro- and 5-deoxy-5,5-difluoro-netilmicin

Carbohydrate research, 1993-01, Vol.238, p.147-162

1993

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Synthesis of 5-deoxy-5-fluoro- and 5-deoxy-5,5-difluoronetilmicin

Carbohydrate research, 1993-01, Vol.238, p.147-162

1993

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Synthesis of low-toxicity, 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of arbekacin and its analogs, and study of structure-toxicity relationships

Carbohydrate research, 1993-02, Vol.240, p.307-312

1993

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Characterization of compound A, a novel lincomycin derivative active against methicillin-resistant Staphylococcus aureus

Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives

Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines

Synthesis and antibacterial activity of novel lincomycin derivatives. IV. Optimization of an N-6 substituent

Synthesis and antibacterial activity of 1-N-[(S)-ω-amino-2-hydroxyalkyl] derivatives of dibekacin, 5-deoxydibekacin, 3'-deoxykanamycin A and gentamicin B

Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities

Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs

Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities

Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity

Aprosamine Derivatives Active against Multidrug-Resistant Gram-Negative Bacteria

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification

Synthesis and antibacterial activity of 1-N-[(S)-[omega]-amino-2-hydroxyalkyl] derivatives of dibekacin, 5-deoxydibekacin, 3[variant prime]-deoxykanamycin A and gentamicin B

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA

SYNTHESIS OF 1-N-(D-THREO-AND RACEMIC ERYTHRO-3-AMINO2-HYDROXYBUTANOYL)-2', 3'-DIDEOXYKANAMYCIN A

SYNTHESIS OF 6''-CHLORO-6''-DEOXYAMIKACIN AND SOME ITS ANALOGS

CP6679, a new injectable cephalosporin. Part1: Synthesis and structure–activity relationships

Synthesis of 5-deoxy-5-epifluoro derivatives of arbekacin, amikacin, and 1- N-[( S)-4-amino-2-hydroxybutanoyl]tobramycin (study on structure — toxicity relationships)

Modification of Aminocyclitol Antibiotics. 6. Preparation of 5-Deoxykanamycin B

CP6679, a new injectable cephalosporin. Part 1: Synthesis and structure-activity relationships

Novel cephalosporin derivatives possessing a bicyclic heterocycle at the 3-position. Part II: Synthesis and antibacterial activity of 3-(5-methylthiazolo[4,5-c]pyridinium-2-yl)-thiomethylcephalosporin derivatives and related compounds

A synthetic study of methyl 3-deoxy-3-fluoro-α- d-glucopyranosides from methyl 2,3-anhydro-α- d-allopyranosides, and synthesis of 3′-deoxy-3′-fluorokanamycin A and 3′-chloro-3′-deoxykanamycin A

Synthesis of 5-deoxy-5-fluoro- and 5-deoxy-5,5-difluoro-netilmicin

Synthesis of 5-deoxy-5-fluoro- and 5-deoxy-5,5-difluoronetilmicin

Synthesis of low-toxicity, 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of arbekacin and its analogs, and study of structure-toxicity relationships

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