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The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation

Biochemical and biophysical research communications, 2017-01, Vol.482 (4), p.1183-1189

2017

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Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice

Antioxidants, 2021-08, Vol.10 (9), p.1398

2021

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Identification of novel selective P2Y 6 receptor antagonists by high-throughput screening assay

Life sciences (1973), 2017-07, Vol.180, p.137-142

2017

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Sphingosine 1-Phosphate May Be a Major Component of Plasma Lipoproteins Responsible for the Cytoprotective Actions in Human Umbilical Vein Endothelial Cells

The Journal of biological chemistry, 2001-08, Vol.276 (34), p.31780-31785

2001

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Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis

International immunopharmacology, 2002-03, Vol.2 (4), p.423-434

2002

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Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

Biochemical journal, 2000-05, Vol.348 Pt 1 (1), p.71-76

2000

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Comparison of Intrinsic Activities of the Putative Sphingosine 1-Phosphate Receptor Subtypes to Regulate Several Signaling Pathways in Their cDNA-transfected Chinese Hamster Ovary Cells

The Journal of biological chemistry, 1999-08, Vol.274 (34), p.23940-23947

1999

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Cytoplasmic OH scavenger TA293 attenuates cellular senescence and fibrosis by activating macrophages through oxidized phospholipids/TLR4

Life sciences (1973), 2019-03, Vol.221, p.284-292

2019

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Identification of novel selective P2Y6 receptor antagonists by high-throughput screening assay

Life sciences (1973), 2017-07, Vol.180, p.137-142

2017

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Possible Involvement of Cell Surface Receptors in Sphingosine 1-Phosphate-Induced Activation of Extracellular Signal-Regulated Kinase in C6 Glioma Cells

Molecular pharmacology, 1999-01, Vol.55 (1), p.126-133

1999

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Enhancement by Adenosine of Insulin-induced Activation of Phosphoinositide 3-Kinase and Protein Kinase B in Rat Adipocytes

The Journal of biological chemistry, 1999-07, Vol.274 (28), p.19545-19550

1999

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TA-270 [4-hydroxy-1-methyl-3-octyloxy-7-sinapinoylamino-2(1H)-quinolinone], an anti-asthmatic agent, inhibits leukotriene production induced by IgE receptor stimulation in RBL-2H3 cells

The Journal of pharmacology and experimental therapeutics, 2003-11, Vol.307 (2), p.583-588

2003

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Study on Action Mode of Sphingosine 1-Phosphate in Rat Hepatocytes

Journal of Pharmacological Sciences, 2005, Vol.97(3), pp.443-446

2005

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Cyclic AMP-increasing Agents Interfere with Chemoattractant-induced Respiratory Burst in Neutrophils as a Result of the Inhibition of Phosphatidylinositol 3-Kinase Rather than Receptor-operated Ca Influx

The Journal of biological chemistry, 1995-10, Vol.270 (40), p.23816

1995

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Differential change of Ins-P3-Ca2+ signaling during culture of rat hepatocytes

Cellular signalling, 2005-01, Vol.17 (1), p.83-91

2005

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Alanine Exchanges of Polar Amino Acids in the Transmembrane Domains of a Platelet-activating Factor Receptor Generate Both Constitutively Active and Inactive Mutants

The Journal of biological chemistry, 1997-03, Vol.272 (12), p.7846-7854

1997

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Identification of novel selective P2Y^sub 6^ receptor antagonists by high-throughput screening assay

Life sciences (1973), 2017-07, Vol.180, p.137

2017

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High Levels of RAE-1 Isoforms on Mouse Tumor Cell Lines Assessed by Anti-“pan” RAE-1 Antibody Confer Tumor Susceptibility to NK Cells

Biochemical and biophysical research communications, 2002-01, Vol.290 (1), p.140-145

2002

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Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells

Brain research. Molecular brain research., 1999-12, Vol.74 (1), p.182-189

1999

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Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells

Brain research. Molecular brain research., 2000-12, Vol.85 (1), p.151-160

2000

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Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase

Trends in Biochemical Sciences, 1995-08, Vol.20 (8), p.303-307

1995

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Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion production

Biochemical journal, 1999-01, Vol.337 ( Pt 2) (2), p.201-209

1999

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Downregulation of mRNA Expression of Edg-3, a Putative Sphingosine 1-Phosphate Receptor Coupled to Ca2+Signaling, during Differentiation of HL-60 Leukemia Cells

Biochemical and biophysical research communications, 1998-12, Vol.253 (2), p.253-256

1998

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Participation of adenosine 5′-triphosphate in the activation of membrane-bound guanylate cyclase by the atrial natriuretic factor

FEBS letters, 1987-07, Vol.219 (2), p.375-379

1987

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Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin

The Journal of biological chemistry, 1994-02, Vol.269 (5), p.3568-3573

1994

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The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation

Effects of the Cytoplasm and Mitochondrial Specific Hydroxyl Radical Scavengers TA293 and mitoTA293 in Bleomycin-Induced Pulmonary Fibrosis Model Mice

Identification of novel selective P2Y 6 receptor antagonists by high-throughput screening assay

Sphingosine 1-Phosphate May Be a Major Component of Plasma Lipoproteins Responsible for the Cytoprotective Actions in Human Umbilical Vein Endothelial Cells

Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis

Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

Comparison of Intrinsic Activities of the Putative Sphingosine 1-Phosphate Receptor Subtypes to Regulate Several Signaling Pathways in Their cDNA-transfected Chinese Hamster Ovary Cells

Cytoplasmic OH scavenger TA293 attenuates cellular senescence and fibrosis by activating macrophages through oxidized phospholipids/TLR4

Identification of novel selective P2Y6 receptor antagonists by high-throughput screening assay

Possible Involvement of Cell Surface Receptors in Sphingosine 1-Phosphate-Induced Activation of Extracellular Signal-Regulated Kinase in C6 Glioma Cells

Enhancement by Adenosine of Insulin-induced Activation of Phosphoinositide 3-Kinase and Protein Kinase B in Rat Adipocytes

TA-270 [4-hydroxy-1-methyl-3-octyloxy-7-sinapinoylamino-2(1H)-quinolinone], an anti-asthmatic agent, inhibits leukotriene production induced by IgE receptor stimulation in RBL-2H3 cells

Study on Action Mode of Sphingosine 1-Phosphate in Rat Hepatocytes

Cyclic AMP-increasing Agents Interfere with Chemoattractant-induced Respiratory Burst in Neutrophils as a Result of the Inhibition of Phosphatidylinositol 3-Kinase Rather than Receptor-operated Ca Influx

Differential change of Ins-P3-Ca2+ signaling during culture of rat hepatocytes

Alanine Exchanges of Polar Amino Acids in the Transmembrane Domains of a Platelet-activating Factor Receptor Generate Both Constitutively Active and Inactive Mutants

Identification of novel selective P2Y^sub 6^ receptor antagonists by high-throughput screening assay

High Levels of RAE-1 Isoforms on Mouse Tumor Cell Lines Assessed by Anti-“pan” RAE-1 Antibody Confer Tumor Susceptibility to NK Cells

Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells

Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase

Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion production

Downregulation of mRNA Expression of Edg-3, a Putative Sphingosine 1-Phosphate Receptor Coupled to Ca2+Signaling, during Differentiation of HL-60 Leukemia Cells

Participation of adenosine 5′-triphosphate in the activation of membrane-bound guanylate cyclase by the atrial natriuretic factor

Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin

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