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The neurobiology of addiction

Annals of the New York Academy of Sciences, 2019-09, Vol.1451 (1), p.5-28

2019

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PTPRD: neurobiology, genetics, and initial pharmacology of a pleiotropic contributor to brain phenotypes

Annals of the New York Academy of Sciences, 2019-09, Vol.1451 (1), p.112-129

2019

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Selecting the appropriate hurdles and endpoints for pentilludin, a novel antiaddiction pharmacotherapeutic targeting the receptor type protein tyrosine phosphatase D

Frontiers in psychiatry, 2023-04, Vol.14, p.1031283-1031283

Uhl, George R

2023

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Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice Via a Possible Central Action

Neurochemical research, 2023-07, Vol.48 (7), p.2230-2240

2023

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Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

PloS one, 2008-02, Vol.3 (2), p.e1640

2008

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Implications of genome wide association studies for addiction: Are our a priori assumptions all wrong?

Pharmacology & therapeutics (Oxford), 2013-12, Vol.140 (3), p.267-279

2013

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Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain

Brain research, 2006-02, Vol.1071 (1), p.10-23

2006

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Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence

PloS one, 2011-07, Vol.6 (7), p.e19210

2011

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Serotonin/dopamine interactions in a hyperactive mouse: reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout

PloS one, 2014-12, Vol.9 (12), p.e115009-e115009

2014

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Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes

Annals of the New York Academy of Sciences, 2015-09, Vol.1349 (1), p.83-95

2015

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Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects

Annals of the New York Academy of Sciences, 2008-10, Vol.1141 (1), p.318-381

2008

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Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation

Sleep medicine, 2017-03, Vol.31, p.71-77

2017

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Role of glycogen synthase kinase-3β in dependence and abuse liability of alcohol

Alcohol and alcoholism (Oxford), 2024-01, Vol.59 (2)

2024

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Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.11597-11602

2018

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Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-127

Journal of pharmacological sciences, 2023-03, Vol.151 (3), p.135-141

2023

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Preface for Addiction Reviews

Annals of the New York Academy of Sciences, 2014-10, Vol.1327 (1), p.v-v

Uhl, George R.

2014

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Altered neurocircuitry in the dopamine transporter knockout mouse brain

PloS one, 2010-07, Vol.5 (7), p.e11506-e11506

2010

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Substrate-selective positive allosteric modulation of PTPRD’s phosphatase by flavonols

Biochemical pharmacology, 2022-08, Vol.202, p.115109-115109, Article 115109

2022

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Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

The New England journal of medicine, 2008-08, Vol.359 (9), p.918-927

2008

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Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes

PloS one, 2013-09, Vol.8 (9), p.e68245

2013

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Curious cases: Altered dose-response relationships in addiction genetics

Pharmacology & therapeutics (Oxford), 2014-03, Vol.141 (3), p.335-346

2014

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Opioid receptor antagonists reduce motivated wheel-running behavior in mice

Behavioural pharmacology, 2024-04, Vol.35 (2-3), p.114

2024

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Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

JNCI : Journal of the National Cancer Institute, 2012-05, Vol.104 (10), p.740-748

2012

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Dopamine compartmentalization, selective dopaminergic vulnerabilities in Parkinson's disease and therapeutic opportunities

Annals of clinical and translational neurology, 2019-02, Vol.6 (2), p.406-415

Uhl, George R.

2019

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Discovery of the Presence and Functional Expression of Cannabinoid CB2 Receptors in Brain

Annals of the New York Academy of Sciences, 2006-08, Vol.1074 (1), p.514-536

2006

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The neurobiology of addiction

PTPRD: neurobiology, genetics, and initial pharmacology of a pleiotropic contributor to brain phenotypes

Selecting the appropriate hurdles and endpoints for pentilludin, a novel antiaddiction pharmacotherapeutic targeting the receptor type protein tyrosine phosphatase D

Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice Via a Possible Central Action

Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

Implications of genome wide association studies for addiction: Are our a priori assumptions all wrong?

Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain

Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence

Serotonin/dopamine interactions in a hyperactive mouse: reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout

Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes

Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects

Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation

Role of glycogen synthase kinase-3β in dependence and abuse liability of alcohol

Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-127

Preface for Addiction Reviews

Altered neurocircuitry in the dopamine transporter knockout mouse brain

Substrate-selective positive allosteric modulation of PTPRD’s phosphatase by flavonols

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes

Curious cases: Altered dose-response relationships in addiction genetics

Opioid receptor antagonists reduce motivated wheel-running behavior in mice

Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

Dopamine compartmentalization, selective dopaminergic vulnerabilities in Parkinson's disease and therapeutic opportunities

Discovery of the Presence and Functional Expression of Cannabinoid CB2 Receptors in Brain

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