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Small molecule targeting r(UGGAA) n disrupts RNA foci and alleviates disease phenotype in Drosophila model

Nature communications, 2021-01, Vol.12 (1), p.236-13, Article 236

2021

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Wolbachia Protein TomO Targets nanos mRNA and Restores Germ Stem Cells in Drosophila Sex-lethal Mutants

Current biology, 2016-09, Vol.26 (17), p.2223-2232

2016

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Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD

Human molecular genetics, 2023-05, Vol.32 (10), p.1673-1682

2023

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Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors

Scientific reports, 2023-12, Vol.13 (1), p.22826-22826, Article 22826

2023

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Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31

Neuron (Cambridge, Mass.), 2017-04, Vol.94 (1), p.108-124.e7

2017

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Parkinson’s disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking

Human molecular genetics, 2018-03, Vol.27 (5), p.823-836

2018

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Wolbachia-mediated male killing is associated with defective chromatin remodeling

PloS one, 2012-01, Vol.7 (1), p.e30045-e30045

2012

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E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease

PloS one, 2019-06, Vol.14 (6), p.e0218261

2019

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p62 Plays a Protective Role in the Autophagic Degradation of Polyglutamine Protein Oligomers in Polyglutamine Disease Model Flies

The Journal of biological chemistry, 2015-01, Vol.290 (3), p.1442-1453

2015

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Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD

Acta neuropathologica communications, 2024-02, Vol.12 (1), p.20-20, Article 20

2024

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Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS

Human molecular genetics, 2014-07, Vol.23 (13), p.3467-3480

2014

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Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS

Experimental cell research, 2018-10, Vol.371 (2), p.311-321

2018

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NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene

Scientific reports, 2018-07, Vol.8 (1), p.11291-14, Article 11291

2018

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Increased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndrome

PloS one, 2010-07, Vol.5 (7), p.e11557-e11557

2010

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Functional Analysis of Proteoglycan Galactosyltransferase II RNA Interference Mutant Flies

The Journal of biological chemistry, 2008-03, Vol.283 (10), p.6076-6084

2008

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Mutations in the desat1 gene reduces the production of courtship stimulatory pheromones through a marked effect on fatty acids in Drosophila melanogaster

Insect biochemistry and molecular biology, 2005-08, Vol.35 (8), p.911-920

2005

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Identification and Characterization of a Novel Drosophila 3′-Phosphoadenosine 5′-Phosphosulfate Transporter

The Journal of biological chemistry, 2006-09, Vol.281 (39), p.28508-28517

2006

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Repeat Expansion Disease Models

Drosophila Models for Human Diseases, 2018, Vol.1076, p.63-78

2018

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Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking

Human molecular genetics, 2018-03, Vol.27 (5), p.823-836

2018

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E46K mutant [alpha]-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type [alpha]-synuclein in Drosophila models of Parkinson's disease.(Research Article)

PloS one, 2019-06, Vol.14 (6), p.e0218261

2019

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Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone

Brain (London, England : 1878), 2019-09, Vol.142 (9), p.2845-2859

2019

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Enhanced cost of mating in female sterile mutants of Drosophila melanogaster

Genes & Genetic Systems, 2003, Vol.78(1), pp.29-36

2003

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Ovulation and the suppression of mating in Drosophila melanogaster females: behavioral basis

Behavior genetics, 1997-09, Vol.27 (5), p.483-488

1997

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Small molecule targeting r(UGGAA) n disrupts RNA foci and alleviates disease phenotype in Drosophila model

Wolbachia Protein TomO Targets nanos mRNA and Restores Germ Stem Cells in Drosophila Sex-lethal Mutants

Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD

Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors

Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72 -linked ALS/FTD

Parkinson’s disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking

Wolbachia-mediated male killing is associated with defective chromatin remodeling

E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease

p62 Plays a Protective Role in the Autophagic Degradation of Polyglutamine Protein Oligomers in Polyglutamine Disease Model Flies

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD

Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS

Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS

NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene

Increased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndrome

Functional Analysis of Proteoglycan Galactosyltransferase II RNA Interference Mutant Flies

Mutations in the desat1 gene reduces the production of courtship stimulatory pheromones through a marked effect on fatty acids in Drosophila melanogaster

Identification and Characterization of a Novel Drosophila 3′-Phosphoadenosine 5′-Phosphosulfate Transporter

Repeat Expansion Disease Models

Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking

E46K mutant [alpha]-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type [alpha]-synuclein in Drosophila models of Parkinson's disease.(Research Article)

Arylsulfatase A, a genetic modifier of Parkinson's disease, is an α-synuclein chaperone

Enhanced cost of mating in female sterile mutants of Drosophila melanogaster

FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD

Ovulation and the suppression of mating in Drosophila melanogaster females: behavioral basis

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