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Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards

Nature communications, 2020-06, Vol.11 (1), p.2713-14, Article 2713

2020

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Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination

Cell stem cell, 2019-05, Vol.24 (5), p.821-828.e5

2019

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Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis

The Journal of immunology (1950), 2017-08, Vol.199 (3), p.1069-1085

2017

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Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model

PloS one, 2010-08, Vol.5 (8), p.e12272-e12272

2010

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Systemic Neutrophil Depletion Modulates the Migration and Fate of Transplanted Human Neural Stem Cells to Rescue Functional Repair

The Journal of neuroscience, 2017-09, Vol.37 (38), p.9269-9287

2017

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Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in Spinal Cord-Injured Mice

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (39), p.14069-14074

2005

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Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (24), p.10211-10216

2007

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Safety of Human Neural Stem Cell Transplantation in Chronic Spinal Cord Injury

Stem cells translational medicine, 2013-12, Vol.2 (12), p.961-974

2013

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Direct Isolation of Human Central Nervous System Stem Cells

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14720-14725

2000

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Prospective isolation of neural stem and progenitor cells from the developing human brain

STAR protocols, 2023-12, Vol.4 (4), p.102674-102674, Article 102674

2023

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Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery

PloS one, 2009-06, Vol.4 (6), p.e5871

2009

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Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis

Cell stem cell, 2009-09, Vol.5 (3), p.310-319

2009

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Injury to the spinal cord niche alters the engraftment dynamics of human neural stem cells

Stem cell reports, 2014-05, Vol.2 (5), p.620-632

2014

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Transplantation dose alters the dynamics of human neural stem cell engraftment, proliferation and migration after spinal cord injury

Stem cell research, 2015-09, Vol.15 (2), p.341-353

2015

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Increasing Human Neural Stem Cell Transplantation Dose Alters Oligodendroglial and Neuronal Differentiation after Spinal Cord Injury

Stem cell reports, 2017-06, Vol.8 (6), p.1534-1548

2017

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Safety of Epicenter Versus Intact Parenchyma as a Transplantation Site for Human Neural Stem Cells for Spinal Cord Injury Therapy

Stem cells translational medicine, 2013-03, Vol.2 (3), p.204-216

2013

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CRISPR/Cas9 Genome Engineering in Engraftable Human Brain-Derived Neural Stem Cells

iScience, 2019-05, Vol.15, p.524-535

2019

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Engraftment of sorted/expanded human central nervous system stem cells from fetal brain

Journal of neuroscience research, 2002-09, Vol.69 (6), p.976-986

2002

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Immunosuppressants Affect Human Neural Stem Cells In Vitro but Not in an In Vivo Model of Spinal Cord Injury

Stem cells translational medicine, 2013-10, Vol.2 (10), p.731-744

2013

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An fMRI study of tool-use gestures: body part as object and pantomime

Neuroreport, 2004-08, Vol.15 (12), p.1903-1906

2004

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MicroRNA-9 Controls a Migratory Mechanism in Human Neural Progenitor Cells

Cell stem cell, 2010-04, Vol.6 (4), p.294-296

Uchida, Nobuko

2010

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HIV, but Not Murine Leukemia Virus, Vectors Mediate High Efficiency Gene Transfer into Freshly Isolated G0/G1 Human Hematopoietic Stem Cells

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.11939-11944

1998

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CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells

Nature (London), 2016-11, Vol.539 (7629), p.384-389

2016

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Transduction of Human Progenitor Hematopoietic Stem Cells by Human Immunodeficiency Virus Type 1-Based Vectors Is Cell Cycle Dependent

Journal of Virology, 1999-05, Vol.73 (5), p.3649-3660

1999

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182 Purification and Characterization of Human Neural Stem and Progenitor Cells

Neurosurgery, 2024-04, Vol.70 (Supplement_1), p.45-46

2024

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Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards

Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination

Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis

Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model

Systemic Neutrophil Depletion Modulates the Migration and Fate of Transplanted Human Neural Stem Cells to Rescue Functional Repair

Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in Spinal Cord-Injured Mice

Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI

Safety of Human Neural Stem Cell Transplantation in Chronic Spinal Cord Injury

Direct Isolation of Human Central Nervous System Stem Cells

Prospective isolation of neural stem and progenitor cells from the developing human brain

Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery

Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis

Injury to the spinal cord niche alters the engraftment dynamics of human neural stem cells

Transplantation dose alters the dynamics of human neural stem cell engraftment, proliferation and migration after spinal cord injury

Increasing Human Neural Stem Cell Transplantation Dose Alters Oligodendroglial and Neuronal Differentiation after Spinal Cord Injury

Safety of Epicenter Versus Intact Parenchyma as a Transplantation Site for Human Neural Stem Cells for Spinal Cord Injury Therapy

CRISPR/Cas9 Genome Engineering in Engraftable Human Brain-Derived Neural Stem Cells

Engraftment of sorted/expanded human central nervous system stem cells from fetal brain

Immunosuppressants Affect Human Neural Stem Cells In Vitro but Not in an In Vivo Model of Spinal Cord Injury

An fMRI study of tool-use gestures: body part as object and pantomime

MicroRNA-9 Controls a Migratory Mechanism in Human Neural Progenitor Cells

HIV, but Not Murine Leukemia Virus, Vectors Mediate High Efficiency Gene Transfer into Freshly Isolated G0/G1 Human Hematopoietic Stem Cells

CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells

Transduction of Human Progenitor Hematopoietic Stem Cells by Human Immunodeficiency Virus Type 1-Based Vectors Is Cell Cycle Dependent

182 Purification and Characterization of Human Neural Stem and Progenitor Cells

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