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Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.516-525

2010

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Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

European journal of pharmaceutical sciences, 2005, Vol.24 (1), p.123-132

2005

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Functional expression, inhibition and induction of CYP enzymes in HepaRG cells

Toxicology in vitro, 2009-06, Vol.23 (4), p.748-753

2009

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Use of comprehensive screening methods to detect selective human CAR activators

Biochemical pharmacology, 2011-12, Vol.82 (12), p.1994-2007

2011

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Prediction of Drug Metabolism and Interactions on the Basis of in vitro Investigations

Basic & clinical pharmacology & toxicology, 2005-03, Vol.96 (3), p.167-175

2005

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Effects of ospemifene on drug metabolism mediated by cytochrome P450 enzymes in humans in vitro and in vivo

International journal of molecular sciences, 2013-07, Vol.14 (7), p.14064-14075

2013

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Timolol metabolism in human liver microsomes is mediated principally by CYP2D6

Drug metabolism and disposition, 2007-07, Vol.35 (7), p.1135-1141

2007

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Comparison of product ion spectra obtained by liquid chromatography/triple-quadrupole mass spectrometry for library search

Rapid communications in mass spectrometry, 2004-01, Vol.18 (10), p.1039-1046

2004

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In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies

Journal of mass spectrometry., 2007-07, Vol.42 (7), p.960-966

2007

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Effect of Clopidogrel and Ticlopidine on Cytochrome P450 2B6 Activity as Measured by Bupropion Hydroxylation

Clinical pharmacology and therapeutics, 2005-06, Vol.77 (6), p.553-559

2005

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Optimum Harvesting Time of Four Mentha Species in Northern Finland

The Journal of essential oil research, 2006-03, Vol.18 (2), p.134-138

2006

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Fast screening method for the analysis of total flavonoid content in plants and foodstuffs by high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry with polarity switching

Rapid communications in mass spectrometry, 2004-01, Vol.18 (24), p.3113-3122

2004

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Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene

Biopharmaceutics & drug disposition, 2013-10, Vol.34 (7), p.387-395

2013

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Metabolism and metabolite profiles in vitro and in vivo of ospemifene in humans and preclinical species

Drug metabolism and personalized therapy, 2016-03, Vol.31 (1), p.35-40

2016

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Inhibition of cytochrome P450 2B6 activity by hormone replacement therapy and oral contraceptive as measured by bupropion hydroxylation

Clinical pharmacology and therapeutics, 2003-10, Vol.74 (4), p.326-333

2003

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Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts

Bone (New York, N.Y.), 2006-11, Vol.39 (5), p.1026-1034

2006

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Metabolic and efflux properties of caco-2 cells stably transfected with nuclear receptors

Pharmaceutical research, 2006-09, Vol.23 (9), p.1991-2001

2006

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Ophthalmic timolol in a hydrogel vehicle leads to minor inter-individual variation in timolol concentration in aqueous humor

European journal of pharmaceutical sciences, 2009-02, Vol.36 (2-3), p.292-296

2009

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A simple method for differentiation of monoisotopic drug metabolites with hydrogen–deuterium exchange liquid chromatography/electrospray mass spectrometry

European journal of pharmaceutical sciences, 2005-05, Vol.25 (1), p.155-162

2005

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Cytochrome P450 (CYP) inhibition screening: Comparison of three tests

European journal of pharmaceutical sciences, 2006-10, Vol.29 (2), p.130-138

2006

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Determination of naphthodianthrones and phloroglucinols from Hypericum perforatum extracts by liquid chromatography/tandem mass spectrometry

Rapid communications in mass spectrometry, 2002-01, Vol.16 (5), p.396-402

2002

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Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis

ALTEX, alternatives to animal experimentation, 2009, Vol.26 (3), p.214-222

2009

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The role of CYP2C and CYP3A in the disposition of 3‐keto‐desogestrel after administration of desogestrel

British journal of clinical pharmacology, 2005-07, Vol.60 (1), p.69-75

2005

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Regional and habitat differences in 7-methyljuglone content of Finnish Drosera rotundifolia

Phytochemistry (Oxford), 2003-06, Vol.63 (3), p.309-314

2003

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Corrigendum to “Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay” [Eur. J. Pharm. Sci. 24 (2005) 123–132]

European journal of pharmaceutical sciences, 2005-03, Vol.24 (4), p.389-389

2005

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Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells

Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

Functional expression, inhibition and induction of CYP enzymes in HepaRG cells

Use of comprehensive screening methods to detect selective human CAR activators

Prediction of Drug Metabolism and Interactions on the Basis of in vitro Investigations

Effects of ospemifene on drug metabolism mediated by cytochrome P450 enzymes in humans in vitro and in vivo

Timolol metabolism in human liver microsomes is mediated principally by CYP2D6

Comparison of product ion spectra obtained by liquid chromatography/triple-quadrupole mass spectrometry for library search

In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies

Effect of Clopidogrel and Ticlopidine on Cytochrome P450 2B6 Activity as Measured by Bupropion Hydroxylation

Optimum Harvesting Time of Four Mentha Species in Northern Finland

Fast screening method for the analysis of total flavonoid content in plants and foodstuffs by high-performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry with polarity switching

Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene

Metabolism and metabolite profiles in vitro and in vivo of ospemifene in humans and preclinical species

Inhibition of cytochrome P450 2B6 activity by hormone replacement therapy and oral contraceptive as measured by bupropion hydroxylation

Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts

Metabolic and efflux properties of caco-2 cells stably transfected with nuclear receptors

Ophthalmic timolol in a hydrogel vehicle leads to minor inter-individual variation in timolol concentration in aqueous humor

A simple method for differentiation of monoisotopic drug metabolites with hydrogen–deuterium exchange liquid chromatography/electrospray mass spectrometry

Cytochrome P450 (CYP) inhibition screening: Comparison of three tests

Determination of naphthodianthrones and phloroglucinols from Hypericum perforatum extracts by liquid chromatography/tandem mass spectrometry

Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis

The role of CYP2C and CYP3A in the disposition of 3‐keto‐desogestrel after administration of desogestrel

Regional and habitat differences in 7-methyljuglone content of Finnish Drosera rotundifolia

Corrigendum to “Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay” [Eur. J. Pharm. Sci. 24 (2005) 123–132]

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