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Medicinal Chemistry: Challenges and Opportunities

Angewandte Chemie (International ed.), 2001-09, Vol.40 (18), p.3341-3350

2001

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Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-ray Crystallography

Journal of medicinal chemistry, 2005-07, Vol.48 (14), p.4511-4525

2005

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Novel factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of P4 substituents in combination with a neutral P1 ligand

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4197-4201

2004

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Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (11), p.2801-2805

2004

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Natural product syntheses based on asymmetric Diels-Alder reactions

Pure and applied chemistry, 1989-01, Vol.61 (3), p.409-412

1989

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Modified bile acids as carriers for peptides and drugs

Journal of controlled release, 1997-05, Vol.46 (1-2), p.17-30

1997

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Intestinal absorption of peptides by coupling to bile acids

The Journal of biological chemistry, 1994-04, Vol.269 (14), p.10621-10627

1994

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Building Blocks for the Synthesis of Enantiomerically Pure Jasmonoids: Synthesis of (+)-Methyl Epijasmonate

Angewandte Chemie (International ed.), 1990-09, Vol.29 (9), p.1024-1025

1990

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Specific Inhibitors of Ileal Bile Acid Transport

Journal of medicinal chemistry, 1994-04, Vol.37 (7), p.873-875

1994

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Synthesis and Biological Activity of Bile Acid-Derived HMG-CoA Reductase Inhibitors. The Role of 21-Methyl in Recognition of HMG-CoA Reductase and the Ileal Bile Acid Transport System

Journal of medicinal chemistry, 1994-09, Vol.37 (20), p.3240-3246

1994

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Bausteine zur Synthese von enantiomerenreinen Jasmonoiden: Synthese von (+)-Methylepijasmonat

Angewandte Chemie, 1990-09, Vol.102 (9), p.1079-1081

1990

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Intestinal absorption of peptides by coupling to bile acids

Hepatology (Baltimore, Md.), 1993-10, Vol.18 (4), p.A299-A299

1993

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Subunit composition of the [formula omitted] acid cotransport system from rabbit ileum

Hepatology (Baltimore, Md.), 1993, Vol.18 (4), p.A299-A299

1993

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ChemInform Abstract: Synthons for the Preparation of Enantiomerically Pure Jasmonoids: Synthesis of (+)‐Methyl Epijasmonate

ChemInform, 1990-11, Vol.21 (48), p.no-no

1990

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ChemInform Abstract: Natural Product Syntheses Based on Asymmetric Diels‐Alder Reactions

ChemInform, 1990-04, Vol.21 (16), p.no-no

1990

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Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy

The European respiratory journal, 2022-03, Vol.59 (3), p.2101798

2022

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6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells

Cellular physiology and biochemistry, 2018-11, Vol.51 (2), p.543-556

2018

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Neuroregenerative Potential of Prenyl- and Pyranochalcones: A Structure–Activity Study

Journal of natural products (Washington, D.C.), 2021-10, Vol.84 (10), p.2675-2682

2021

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Photochemical Properties of the Red‐shifted Channelrhodopsin Chrimson

Photochemistry and photobiology, 2017-05, Vol.93 (3), p.782-795

2017

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Improved Synthesis of Indirubin Derivatives by Sequential Build-Up of the Indoxyl Unit: First Preparation of Fluorescent Indirubins

Helvetica chimica acta, 2012-08, Vol.95 (8), p.1461-1477

2012

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Optical limiter coatings towards reusable high irradiance shielding

Optical materials, 2022-11, Vol.133, p.112989, Article 112989

2022

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Central composite design for optimal technology of concentrating vanillic acid using foam fractionation

Separation and purification technology, 2013, Vol.119, p.28-34

2013

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New Field Method: Gas Push−Pull Test for the In-Situ Quantification of Microbial Activities in the Vadose Zone

Environmental science & technology, 2005-01, Vol.39 (1), p.304-310

2005

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Retaining cocaine-abusing women in a therapeutic community: the effect of a child live-in program

American journal of public health (1971), 1995-08, Vol.85 (8 Pt 1), p.1149-1152

1995

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Inhibition of Histone Deacetlases Using Flavonoids from Hops

Planta Medica International Open, 2017, Vol.4 (S 01)

2017

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Medicinal Chemistry: Challenges and Opportunities

Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-ray Crystallography

Novel factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of P4 substituents in combination with a neutral P1 ligand

Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand

Natural product syntheses based on asymmetric Diels-Alder reactions

Modified bile acids as carriers for peptides and drugs

Intestinal absorption of peptides by coupling to bile acids

Building Blocks for the Synthesis of Enantiomerically Pure Jasmonoids: Synthesis of (+)-Methyl Epijasmonate

Specific Inhibitors of Ileal Bile Acid Transport

Synthesis and Biological Activity of Bile Acid-Derived HMG-CoA Reductase Inhibitors. The Role of 21-Methyl in Recognition of HMG-CoA Reductase and the Ileal Bile Acid Transport System

Bausteine zur Synthese von enantiomerenreinen Jasmonoiden: Synthese von (+)-Methylepijasmonat

Intestinal absorption of peptides by coupling to bile acids

Subunit composition of the [formula omitted] acid cotransport system from rabbit ileum

ChemInform Abstract: Synthons for the Preparation of Enantiomerically Pure Jasmonoids: Synthesis of (+)‐Methyl Epijasmonate

ChemInform Abstract: Natural Product Syntheses Based on Asymmetric Diels‐Alder Reactions

Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy

6- and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells

Neuroregenerative Potential of Prenyl- and Pyranochalcones: A Structure–Activity Study

Photochemical Properties of the Red‐shifted Channelrhodopsin Chrimson

Improved Synthesis of Indirubin Derivatives by Sequential Build-Up of the Indoxyl Unit: First Preparation of Fluorescent Indirubins

Optical limiter coatings towards reusable high irradiance shielding

Central composite design for optimal technology of concentrating vanillic acid using foam fractionation

New Field Method: Gas Push−Pull Test for the In-Situ Quantification of Microbial Activities in the Vadose Zone

Retaining cocaine-abusing women in a therapeutic community: the effect of a child live-in program

Inhibition of Histone Deacetlases Using Flavonoids from Hops

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