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Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

Reproductive toxicology (Elmsford, N.Y.), 1998-07, Vol.12 (4), p.457-463

1998

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Disposition of ivermectin and cyclosporin A in CF-1 mice deficient in mdr1a P-glycoprotein

Drug metabolism and disposition, 1999-05, Vol.27 (5), p.581

1999

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Identification of a P-Glycoprotein-Deficient Subpopulation in the CF-1 Mouse Strain Using a Restriction Fragment Length Polymorphism

Toxicology and applied pharmacology, 1997-09, Vol.146 (1), p.88-94

1997

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Isolation and Sequence Determination of a cDNA Clone Related to Human Cytochrome P-450 Nifedipine Oxidase

Proceedings of the National Academy of Sciences - PNAS, 1986-11, Vol.83 (21), p.8064-8068

1986

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Altered Expression of Hepatic Cytochromes P-450 in Mice Deficient in One or More mdr1 Genes

Molecular pharmacology, 2000-01, Vol.57 (1), p.188-197

2000

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Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

Biochemistry (Easton), 1988-09, Vol.27 (18), p.6929-6940

1988

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Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase

Biochemistry (Easton), 1987-02, Vol.26 (4), p.1094-1099

1987

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CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans

Drug metabolism and disposition, 1993-11, Vol.21 (6), p.1029

1993

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Human liver S-9 metabolic activation : Proficiency in cytogenetic assays and comparison with phenobarbital/β-naphthoflavone or aroclor 1254 induced rat S-9

Environmental and molecular mutagenesis, 1996, Vol.28 (1), p.51-59

1996

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The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene

Journal of biochemical and molecular toxicology, 2001, Vol.15 (2), p.83-89

2001

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Karyotypic and phenotypic changes during in vitro aging of human endothelial cells

Journal of cellular physiology, 1992-01, Vol.150 (1), p.17-27

1992

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Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae

Biochemistry (Easton), 1989-06, Vol.28 (12), p.4993-4999

1989

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Cell-Specific Differences in O6-alkylguanine DNA Repair Activity during Continuous Exposure to Carcinogen

Proceedings of the National Academy of Sciences - PNAS, 1982-09, Vol.79 (18), p.5499-5502

1982

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Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone

Toxicology and applied pharmacology, 2004-11, Vol.200 (3), p.237-250

2004

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Mutagenic response of the endogenous hprt gene and lacl transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice

Environmental and molecular mutagenesis (Print), 1996, Vol.28 (4), p.376-384

1996

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Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A

Journal of biochemical and molecular toxicology, 2001, Vol.15 (3), p.133-142

2001

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Human-liver cytochromes P-450 involved in polymorphisms of drug oxidation

Xenobiotica, 1986, Vol.16 (5), p.367-378

1986

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Statins and PPARα agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment

Toxicology and applied pharmacology, 2005-11, Vol.208 (3), p.210-221

2005

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Polymorphism of human cytochrome P-450

Xenobiotica, 1987, Vol.17 (3), p.311-316

1987

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Cytochrome P-450 enzymes involved in genetic polymorphism of drug oxidation in humans

Biochemical Society transactions, 1987-08, Vol.15 (4), p.576-578

1987

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Alkylation of intracellular and extracellular DNA by dimethylnitrosamine following activation by isolated rat hepatocytes

Cancer research (Chicago, Ill.), 1981-09, Vol.41 (9 Pt 1), p.3471-3474

1981

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Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresson

The Journal of biological chemistry, 2001-08, Vol.276 (34), p.31521-31527

2001

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Structure and function of cytochrome P-450

Advances in experimental medicine and biology, 1986, Vol.197, p.83

1986

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Metabolism of dimethylnitrosamine and subsequent removal of O6-methylguanine from DNA by isolated rat hepatocytes

Chemico-biological interactions, 1981-01, Vol.33 (2-3), p.229-238

1981

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Human Liver Mephenytoin 4 -Hydroxylase Cytochrome P-450 Proteins and Genes

Drug metabolism reviews, 1989, Vol.20 (2-4), p.449-465

1989

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Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

Disposition of ivermectin and cyclosporin A in CF-1 mice deficient in mdr1a P-glycoprotein

Identification of a P-Glycoprotein-Deficient Subpopulation in the CF-1 Mouse Strain Using a Restriction Fragment Length Polymorphism

Isolation and Sequence Determination of a cDNA Clone Related to Human Cytochrome P-450 Nifedipine Oxidase

Altered Expression of Hepatic Cytochromes P-450 in Mice Deficient in One or More mdr1 Genes

Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase

CYP1A1 specificity of Verlukast epoxidation in mice, rats, rhesus monkeys, and humans

Human liver S-9 metabolic activation : Proficiency in cytogenetic assays and comparison with phenobarbital/β-naphthoflavone or aroclor 1254 induced rat S-9

The subpopulation of CF-1 mice deficient in P-glycoprotein contains a murine retroviral insertion in the mdr1a gene

Karyotypic and phenotypic changes during in vitro aging of human endothelial cells

Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae

Cell-Specific Differences in O6-alkylguanine DNA Repair Activity during Continuous Exposure to Carcinogen

Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone

Mutagenic response of the endogenous hprt gene and lacl transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice

Use of real-time gene-specific polymerase chain reaction to measure RNA expression of three family members of rat cytochrome P450 4A

Human-liver cytochromes P-450 involved in polymorphisms of drug oxidation

Statins and PPARα agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment

Polymorphism of human cytochrome P-450

Cytochrome P-450 enzymes involved in genetic polymorphism of drug oxidation in humans

Alkylation of intracellular and extracellular DNA by dimethylnitrosamine following activation by isolated rat hepatocytes

Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha. PPAR alpha fails to induce peroxisome proliferation-associated genes in human cells independently of the level of receptor expresson

Structure and function of cytochrome P-450

Metabolism of dimethylnitrosamine and subsequent removal of O6-methylguanine from DNA by isolated rat hepatocytes

Human Liver Mephenytoin 4 -Hydroxylase Cytochrome P-450 Proteins and Genes

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