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PTPRD: neurobiology, genetics, and initial pharmacology of a pleiotropic contributor to brain phenotypes

Annals of the New York Academy of Sciences, 2019-09, Vol.1451 (1), p.112-129

2019

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Selecting the appropriate hurdles and endpoints for pentilludin, a novel antiaddiction pharmacotherapeutic targeting the receptor type protein tyrosine phosphatase D

Frontiers in psychiatry, 2023-04, Vol.14, p.1031283-1031283

Uhl, George R

2023

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Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice Via a Possible Central Action

Neurochemical research, 2023-07, Vol.48 (7), p.2230-2240

2023

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Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain

Brain research, 2006-02, Vol.1071 (1), p.10-23

2006

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Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.11597-11602

2018

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Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes

Annals of the New York Academy of Sciences, 2015-09, Vol.1349 (1), p.83-95

2015

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Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

PloS one, 2008-02, Vol.3 (2), p.e1640

2008

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Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence

PloS one, 2011-07, Vol.6 (7), p.e19210

2011

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Serotonin/dopamine interactions in a hyperactive mouse: reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout

PloS one, 2014-12, Vol.9 (12), p.e115009-e115009

2014

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Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-127

Journal of pharmacological sciences, 2023-03, Vol.151 (3), p.135-141

2023

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Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects

Annals of the New York Academy of Sciences, 2008-10, Vol.1141 (1), p.318-381

2008

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Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

JNCI : Journal of the National Cancer Institute, 2012-05, Vol.104 (10), p.740-748

2012

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Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

The New England journal of medicine, 2008-08, Vol.359 (9), p.918-927

2008

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The neurobiology of addiction

Annals of the New York Academy of Sciences, 2019-09, Vol.1451 (1), p.5-28

2019

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Dopamine compartmentalization, selective dopaminergic vulnerabilities in Parkinson's disease and therapeutic opportunities

Annals of clinical and translational neurology, 2019-02, Vol.6 (2), p.406-415

Uhl, George R.

2019

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Discovery of the Presence and Functional Expression of Cannabinoid CB2 Receptors in Brain

Annals of the New York Academy of Sciences, 2006-08, Vol.1074 (1), p.514-536

2006

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In vivo evaluation of effects of histamine H3 receptor antagonists on methamphetamine-induced hyperlocomotion in mice

Brain research, 2020-08, Vol.1740, p.146873-146873, Article 146873

2020

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Cell Adhesion Molecules: Druggable Targets for Modulating the Connectome and Brain Disorders?

Neuropsychopharmacology (New York, N.Y.), 2014-01, Vol.39 (1), p.235-235

2014

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Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice

Pharmacology, biochemistry and behavior, 2021-10, Vol.209, p.173257-173257, Article 173257

2021

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Altered neurocircuitry in the dopamine transporter knockout mouse brain

PloS one, 2010-07, Vol.5 (7), p.e11506-e11506

2010

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Impaired spatial working memory and decreased frontal cortex BDNF protein level in dopamine transporter knockout mice

European journal of pharmacology, 2010-02, Vol.628 (1), p.104-107

2010

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Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes

PloS one, 2013-09, Vol.8 (9), p.e68245

2013

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Tetrabenazine, a vesicular monoamine transporter-2 inhibitor, attenuates morphine-induced hyperlocomotion in mice through alteration of dopamine and 5-hydroxytryptamine turnover in the cerebral cortex

Pharmacology, biochemistry and behavior, 2018-09, Vol.172, p.9-16

2018

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The Role of Cell Adhesion Molecule Genes Regulating Neuroplasticity in Addiction

Neural plasticity, 2018-01, Vol.2018 (2018), p.1-17

2018

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Brain hyperserotonemia causes autism-relevant social deficits in mice

Molecular autism, 2018-11, Vol.9 (1), p.60-60, Article 60

2018

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PTPRD: neurobiology, genetics, and initial pharmacology of a pleiotropic contributor to brain phenotypes

Selecting the appropriate hurdles and endpoints for pentilludin, a novel antiaddiction pharmacotherapeutic targeting the receptor type protein tyrosine phosphatase D

Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice Via a Possible Central Action

Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain

Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist

Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes

Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence

Serotonin/dopamine interactions in a hyperactive mouse: reduced serotonin receptor 1B activity reverses effects of dopamine transporter knockout

Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-127

Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects

Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

The neurobiology of addiction

Dopamine compartmentalization, selective dopaminergic vulnerabilities in Parkinson's disease and therapeutic opportunities

Discovery of the Presence and Functional Expression of Cannabinoid CB2 Receptors in Brain

In vivo evaluation of effects of histamine H3 receptor antagonists on methamphetamine-induced hyperlocomotion in mice

Cell Adhesion Molecules: Druggable Targets for Modulating the Connectome and Brain Disorders?

Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice

Altered neurocircuitry in the dopamine transporter knockout mouse brain

Impaired spatial working memory and decreased frontal cortex BDNF protein level in dopamine transporter knockout mice

Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes

Tetrabenazine, a vesicular monoamine transporter-2 inhibitor, attenuates morphine-induced hyperlocomotion in mice through alteration of dopamine and 5-hydroxytryptamine turnover in the cerebral cortex

The Role of Cell Adhesion Molecule Genes Regulating Neuroplasticity in Addiction

Brain hyperserotonemia causes autism-relevant social deficits in mice

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