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Nonsteroidal Selective Glucocorticoid Modulators: The Effect of C-10 Substitution on Receptor Selectivity and Functional Potency of 5-Allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

Journal of medicinal chemistry, 2003-03, Vol.46 (6), p.1016-1030

2003

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Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1721-1727

2004

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A Novel Antiinflammatory Maintains Glucocorticoid Efficacy with Reduced Side Effects

Molecular endocrinology (Baltimore, Md.), 2003-05, Vol.17 (5), p.860-869

2003

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Nonsteroidal Selective Glucocorticoid Modulators: the Effect of C-5 Alkyl Substitution on the Transcriptional Activation/Repression Profile of 2,5-Dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

Journal of medicinal chemistry, 2001-12, Vol.44 (25), p.4481-4491

2001

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17β-Estradiol inhibits cytokine induction of the human E-selectin promoter

The Journal of steroid biochemistry and molecular biology, 2002, Vol.80 (3), p.291-297

2002

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The mammalian two-hybrid assay for detection of coactivator-nuclear receptor interactions

Methods in molecular medicine, 2003, Vol.85, p.175

2003

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Drug discovery and the intracellular receptor family

Vitamins and Hormones, 2001, Vol.62, p.253-280

2001

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Structure and Function of the Small Subunit of TFIIF (RAP30) from Drosophilamelanogaster(∗)

The Journal of biological chemistry, 1995-03, Vol.270 (11), p.6292-6297

1995

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Identification of a minimal set of proteins that is sufficient for accurate initiation of transcription by RNA polymerase II

Genes & development, 1993-07, Vol.7 (7A), p.1254-1265

1993

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17beta-Estradiol inhibits cytokine induction of the human E-selectin promoter

The Journal of steroid biochemistry and molecular biology, 2002-03, Vol.80 (3), p.291-297

2002

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Accurate and efficient RNA polymerase II transcription with a soluble nuclear fraction derived from Drosophila embryos

Proceedings of the National Academy of Sciences - PNAS, 1991-02, Vol.88 (3), p.1024-1028

1991

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In vitro transcription of a Drosophila U1 small nuclear RNA gene requires TATA box-binding protein and two proximal cis-acting elements with stringent spacing requirements

Molecular and Cellular Biology, 1993-09, Vol.13 (9), p.5918-5927

1993

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Structure and function of the small subunit of TFIIF (RAP30) from Drosophila melanogaster

The Journal of biological chemistry, 1995-03, Vol.270 (11), p.6292-6297

1995

Volltextzugriff (PDF)

In Vitro Transcription of a Drosophila U1 Small Nuclear RNA Gene Requires TATA Box-Binding Protein and Two Proximal cis-Acting Elements with Stringent Spacing Requirements

Molecular and cellular biology, 1993-09, Vol.13 (9), p.5918-5927

1993

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Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Neuron (Cambridge, Mass.), 2010-09, Vol.67 (5), p.769-780

2010

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Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis

Journal of medicinal chemistry, 2001-10, Vol.44 (22), p.3730-3745

2001

Volltextzugriff (PDF)

Synthesis and Characterization of Non-Steroidal Ligands for the Glucocorticoid Receptor: Selective Quinoline Derivatives with Prednisolone-Equivalent Functional Activity

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.2879-2885

2001

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trans-Activation and Repression Properties of the Novel Nonsteroid Glucocorticoid Receptor Ligand 2,5-Dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and Its Four Stereoisomers

Molecular pharmacology, 2002-08, Vol.62 (2), p.297

2002

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A Nonsteroidal Glucocorticoid Receptor Antagonist

Molecular endocrinology (Baltimore, Md.), 2003-01, Vol.17 (1), p.117-127

2003

Volltextzugriff (PDF)

Modulation of [gamma]-Secretase Reduces [beta]-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Neuron (Cambridge, Mass.), 2010-09, Vol.67 (5), p.769

2010

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The effects of experimental hypercholesterolemia on transposed arterial and venous autografts

The Journal of surgical research, 1975-02, Vol.18 (2), p.163-167

1975

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Nonsteroidal Selective Glucocorticoid Modulators: The Effect of C-10 Substitution on Receptor Selectivity and Functional Potency of 5-Allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

A Novel Antiinflammatory Maintains Glucocorticoid Efficacy with Reduced Side Effects

Nonsteroidal Selective Glucocorticoid Modulators: the Effect of C-5 Alkyl Substitution on the Transcriptional Activation/Repression Profile of 2,5-Dihydro-10-methoxy-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines

17β-Estradiol inhibits cytokine induction of the human E-selectin promoter

The mammalian two-hybrid assay for detection of coactivator-nuclear receptor interactions

Drug discovery and the intracellular receptor family

Structure and Function of the Small Subunit of TFIIF (RAP30) from Drosophilamelanogaster(∗)

Identification of a minimal set of proteins that is sufficient for accurate initiation of transcription by RNA polymerase II

17beta-Estradiol inhibits cytokine induction of the human E-selectin promoter

Accurate and efficient RNA polymerase II transcription with a soluble nuclear fraction derived from Drosophila embryos

In vitro transcription of a Drosophila U1 small nuclear RNA gene requires TATA box-binding protein and two proximal cis-acting elements with stringent spacing requirements

Structure and function of the small subunit of TFIIF (RAP30) from Drosophila melanogaster

In Vitro Transcription of a Drosophila U1 Small Nuclear RNA Gene Requires TATA Box-Binding Protein and Two Proximal cis-Acting Elements with Stringent Spacing Requirements

Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis

Synthesis and Characterization of Non-Steroidal Ligands for the Glucocorticoid Receptor: Selective Quinoline Derivatives with Prednisolone-Equivalent Functional Activity

trans-Activation and Repression Properties of the Novel Nonsteroid Glucocorticoid Receptor Ligand 2,5-Dihydro-9-hydroxy-10-methoxy-2,2,4-trimethyl-5-(1-methylcyclohexen-3-y1)-1H-[1]benzopyrano[3,4-f]quinoline (A276575) and Its Four Stereoisomers

A Nonsteroidal Glucocorticoid Receptor Antagonist

Modulation of [gamma]-Secretase Reduces [beta]-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

The effects of experimental hypercholesterolemia on transposed arterial and venous autografts

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